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杭海英
Life Science
中国科学院大学
北京
Language: 英语, 中文
分子肿瘤学
蛋白质工程
癌症研究
肿瘤生物学
基因工程
生物物理学
细胞生物学
生物化学
分子生物学
生物医学研究
Areas of Focus
- 分子肿瘤学和蛋白质人工进化
Work Experience
- 2004-08 至今 - 中国科学院生物物理研究所 - 研究员
- 2000-01 至 2004-07 - 哥伦比亚大学 - 助理教授
Academic Background & Achievements
- 1988-09 至 1994-01 - 放射生物学博士: 科罗拉多州立大学
- 1983-09 至 1986-07 - 理学硕士: 中国科学院动物研究所
Publications
- Two Distinct States of Escherichia coli Cells That Overexpress Recombinant Heterogeneous β-Galactosidase, 杭海英, 2012
- Affinity maturation of anti-TNF-alpha scFv with somatic hypermutation in non-B cells, 杭海英, 2012
- A role for the arginine methylation of Rad9 in checkpoint control and cellular sensitivity to DNA damage, 杭海英, 2011
- Effects of Simulated Microgravity on Embryonic Stem Cells, 杭海英, 2011
- Targeted deletion of mouse Rad1 leads to deficient cellular DNA damage responses, 杭海英, 2011
- Mouse Rad1 deletion enhances susceptibility for skin tumor development, 杭海英, 2010
- Enrichment of Escherichia coli Spheroplasts Displaying scFv Antibodies specific for antigens expressed on the human cell surface, 杭海英, 2010
- Rad9 is required for B cell proliferation and immunoglobulin class switch recombination, 杭海英, 2010
- Structure and functional implications of the human rad9-hus1-rad1 cell cycle checkpoint complex, 杭海英, 2009
- Phosphorylation Sites on Tyr28 and the C-terminus of Rad9 are Required for Inhibition of Premature Chromosomal Condensation Across the Entire S Phase, 杭海英, 2008
- Rad9 plays an important role in DNA mismatch repair through physical interaction with MLH1, 杭海英, 2008
- Targeted deletion of Rad9 in mouse skin keratinocytes enhances genotoxin-induced tumor development, 杭海英, 2008
- Improving Penetration in Tumors with Nano-assemblies of Phospholipids and Doxorubicin, 杭海英, 2007
