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李俊
Life Science
中国科学院大学
四川
Language: 中文, 英文
内耳
发育
生物学
听觉
毛细胞
再生
基因
表达
调控
研究
Areas of Focus
- 内耳发育生物学
- 听觉毛细胞再生
- 基因表达调控
Work Experience
- 2022-07~现在 - 中国科学院成都生物研究所 - 研究员
- 2013-09~2021-10 - 西奈山医学院 - 博士后
- 2011-05~2013-05 - 中科院遗传与发育生物学研究所 - 博士后
Academic Background & Achievements
- 2005-09--2011-04 硕博连读: 武汉大学
- 2001-09--2005-07 学士学位: 武汉工程大学
Publications
- The transcriptional coactivator Eya1 exerts transcriptional repressive activity by interacting with REST corepressors and REST-binding sequences to maintain nephron progenitor identity, 第一作者, 2022
- Six1 and Six2 of the Sine Oculis Homeobox Subfamily are Not Functionally Interchangeable in Mouse Nephron Formation, 第二作者, 2022
- Chromatin remodelers and lineage-specific factors interact to target enhancers to establish proneurosensory fate within otic ectoderm, 第二作者, 2021
- Chromatin Remodelers Interact with Eya1 and Six2 to Target Enhancers to Control Nephron Progenitor Cell Maintenance, 第一作者, 2021
- Dynamic changes in cis-regulatory occupancy by Six1 and its cooperative interactions with distinct cofactors drive lineage-specific gene expression programs during progressive differentiation of the auditory sensory epithelium, 第一作者, 2020
- EYA1's Conformation Specificity in Dephosphorylating Phosphothreonine in Myc and Its Activity on Myc Stabilization in Breast Cancer, 第一作者, 2017
- Eya1 Interacts with Six2 and Myc to Regulate Expansion of the Nephron Progenitor Pool during Nephrogenesis, 第四作者, 2014
