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梁伟
Life Science
中国科学院大学
北京
Language: 中文, 英语
药物输送
免疫应答
生物大分子
溶酶体
蛋白质平衡
纳米医学
治疗性疫苗
抗原呈递
纳米颗粒
细胞生物学
Areas of Focus
- 生物大分子药物输送系统及免疫应答机制
- 溶酶体在维持蛋白质平衡中的作用
Work Experience
- 2003-10~现在 - 中科院生物物理研究所 - 副研究员，研究员
- 2001-12~2003-10 - 哈佛大学和东北大学 - 研究助理
- 2000-11~2001-12 - 明尼苏达大学 - 博士后
Academic Background & Achievements
- 1997-09--2000-09 博士: 上海医药工业研究院
- 1994-09--1997-06 药剂学硕士: 沈阳药科大学
Publications
- PPAR alpha Inhibition Overcomes Tumor-Derived Exosomal Lipid-Induced Dendritic Cell Dysfunction, Yin, Xiaozhe, Zeng, Wenfeng, Wu, Bowen, Wang, Luoyang, Wang, Zihao, Tian, Hongjian, Wang, Luyao, Jiang, Yunhan, Clay, Ryan, Wei, Xiuli, Qin, Yan, Zhang, Fayun, Zhang, Chunling, Jin, Lingtao, Liang, Wei, 2020
- Delivered antigen peptides to resident CD8 alpha(+) DCs in lymph node by micelle-based vaccine augment antigen-specific CD8(+) effector T cell response, Wang, Luyao, Wang, Zihao, Qin, Yan, Liang, Wei, 2020
- Naringenin Enhances the Antitumor Effect of Therapeutic Vaccines by Promoting Antigen Cross-Presentation, Wang, Luoyang, Zeng, Wenfeng, Wang, Luyao, Wang, Zihao, Yin, Xiaozhe, Qin, Yan, Zhang, Fayun, Zhang, Chunling, Liang, Wei, 2020
- Naringenin Ameliorates Radiation-Induced Lung Injury by Lowering IL-1 beta Level, Zhang, Chao, Zeng, Wenfeng, Yao, Yi, Xu, Bin, Wei, Xiuli, Wang, Luoyang, Yin, Xiaozhe, Barman, Apurba Kumar, Zhang, Fayun, Zhang, Chunling, Song, Qibin, Liang, Wei, 2018
- Chemically Precise Glycoengineering Improves Human Insulin, Guan, Xiaoyang, Chaffey, Patrick K, Wei, Xiuli, Gulbranson, Daniel R, Ruan, Yuan, Wang, Xinfeng, Li, Yaohao, Ouyang, Yan, Chen, Liqun, Zeng, Chen, Koelsch, Theo N, Tran, Amy H, Liang, Wei, Shen, Jingshi, Tan, Zhongping, 2018
- CpG loaded MoS2 nanosheets as multifunctional agents for photothermal enhanced cancer immunotherapy, Han, Qiusen, Wang, Xinhuan, Jia, Xinghang, Cai, Shuangfei, Liang, Wei, Qin, Yan, Yang, Rong, Wang, Chen, 2017
- Coordinating antigen cytosolic delivery and danger signaling to program potent cross-priming by micelle-based nanovaccine, Liu, Zhida, Zhou, Chang, Qin, Yan, Wang, Zihao, Wang, Luyao, Wei, Xiuli, Zhou, Yinjian, Li, Qicheng, Zhou, Hang, Wang, Wenjun, Fu, YangXin, Zhu, Mingzhao, Liang, Wei, 2017
- Naringenin Ameliorates Acute Inflammation by Regulating Intracellular Cytokine Degradation, Wei Liang, 2017
- Nano-cage-mediated refolding of insulin by PEG-PE micelle, Fang, Xiaocui, Yang, Tao, Wang, Luoyang, Yu, Jibing, Wei, Xiuli, Zhou, Yinjian, Wang, Chen, Liang, Wei, 2016
- Naringenin prevents TGF-β1 secretion from breast cancer and suppresses pulmonary metastasis by inhibiting PKC activation, Fayun Zhang, Wenjuan Dong, Wenfeng Zeng, Lei Zhang, Chao Zhang, Yuqi Qiu, Luoyang Wang, Xiaozhe Yin, Chunling Zhang, Wei Liang, 2016
- A dual character of flavonoids in influenza A virus replication and spread through modulating cell-autonomous immunity by MAPK signaling pathways, Dong, Wenjuan, Wei, Xiuli, Zhang, Fayun, Hao, Junfeng, Huang, Feng, Zhang, Chunling, Liang, Wei, 2014
- Poly(ethylene glycol)-mediated conformational alteration of α-chymotrypsin prevents inactivation of insulin by stabilizing active intermediates, Wei Liang, 2014
- Polymeric micelles for enhanced lymphatic drug delivery to treat metastatic tumors, Qin, Lei, Zhang, Fayun, Lu, Xiaoyan, Wei, Xiuli, Wang, Jing, Fang, Xiaocui, Si, Duanyun, Wang, Yiguang, Zhang, Chunling, Yang, Rong, Liu, Changxiao, Liang, Wei, 2013
- Delivery of drugs to cell membranes by encapsulation in PEG-PE micelles, Wang, Jing, Wang, Yiguang, Liang, Wei, 2012
- Pegylated Phospholipid Micelles Induce Endoplasmic Reticulum-Dependent Apoptosis of Cancer Cells but not Normal Cells, Wang, Jing, Fang,
Awards
- 国家科学技术奖, 二等奖 (2012)
- 中国专利优秀奖 (2010)
- 中国科学院“优秀研究生指导教师” (2009)
- 中国药学会科学技术奖, 二等奖 (2008)
