Areas of Focus
- 非编码RNA,干细胞分化
- 表观遗传调控
- 微生物与宿主互作机制
Work Experience
- 2019-09~现在 - 中国科学院深圳先进技术研究院 - 研究员
- 2015-06~2019-09 - 斯坦福大学 - 博士后
Academic Background & Achievements
- 2009-08--2015-05 博士: 约翰霍普金斯大学
- 2005-09--2009-06 学士: 北京大学
Publications
- Inducible lncRNA transgenic mice reveal continual role of HOTAIR in promoting breast cancer metastasis, 第一作者, 2023
- Long noncoding RNA XIST: Mechanisms for X chromosome inactivation, roles in sex-biased diseases, and therapeutic opportunities, 通讯作者, 2022
- The Role of Long Non-coding RNAs in Human Imprinting Disorders: Prospective Therapeutic Targets, 通讯作者, 2022
- Construction of synthetic life forms with genetic materials comprising unnatural nucleic acids, 第六作者, 2021
- Structural modularity of the XIST ribonucleoprotein complex, 第六作者, 2020
- Probing the Function of Metazoan Histones with a Systematic Library of H3 and H4 Mutants, 第五作者, 2019
- The novel lncRNA lnc-NR2F1 is proneurogenic and mutated in human neurodevelopmental disorders, 第二作者, 2019
- PIRCh-seq: functional classification of non-coding RNAs associated with distinct histone modifications, 第二作者, 2019
- Chinmo is sufficient to induce male fate in somatic cells of the adult Drosophila ovary, 第一作者, 2016
- Single-cell profiling of lncRNAs in the developing human brain, 第一作者, 2016
- The Jak-STAT Target Chinmo Prevents Sex Transformation of Adult Stem Cells in the Drosophila Testis Niche, 第一作者, 2014
- Steroid signaling promotes stem cell maintenance in the Drosophila testis, 第二作者, 2014