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孙鲁阳
Life Science
中国科学院大学
山东
Language: 英语, 中文
表观遗传学
基因调控
染色质
Dna甲基化
组蛋白修饰
非编码Rna
基因组学
基因组测序
生物信息学
海洋生物学
Areas of Focus
- 表观遗传学
- 基因组学
- 海洋资源生物
Work Experience
- 2014-12~2021-10 - 美国贝勒医学院 - 博士后
- 2010-08~2014-12 - 美国奥本大学 - 博士生
- 2006-09~2010-06 - 中国海洋大学 - 学士生
Academic Background & Achievements
- 2010-08--2014-12 博士: 美国奥本大学
- 2006-09--2010-06 学士: 中国海洋大学
Publications
- Altered Chromatin States Drive Cryptic Transcription in Aging Mammalian Stem Cells, Nature aging, 2021
- Tracking break-induced replication shows that it stalls at roadblocks, NATURE, 2021
- Inactivating histone deacetylase HDA promotes longevity by mobilizing trehalose metabolism, NATURE COMMUNICATIONS, 2021
- SIRT7 slows down stem cell aging by preserving heterochromatin: a perspective on the new discovery, PROTEIN & CELL, 2020
- CRYPTIC TRANSCRIPTION IS ASSOCIATED WITH AGE IN MAMMALIAN STEM CELLS, Innovation in Aging, 2019
- Cellular response to moderate chromatin architectural defects promotes longevity, SCIENCE ADVANCES, 2019
- YY1-MEDIATED PROMOTER-SUPER ENHANCER INTERACTIONS REGULATE MSC MULTIPOTENCY DURING REPLICATIVE AGING, Innovation in Aging, 2019
- Chromatin Architectural Changes during Cellular Senescence and Aging, GENES, 2018
- GWAS analysis of QTL for enteric septicemia of catfish and their involved genes suggest evolutionary conservation of a molecular mechanism of disease resistance, MOLECULAR GENETICS AND GENOMICS, 2017
- The channel catfish genome sequence provides insights into the evolution of scale formation in teleosts, NATURE COMMUNICATIONS, 2016
- Ribosomal protein genes are highly enriched among genes with allele-specific expression in the interspecific F1 hybrid catfish, MOLECULAR GENETICS AND GENOMICS, 2016
- A genome-wide association study in catfish reveals the presence of functional hubs of related genes within QTLs for columnaris disease resistance, BMC Genomics, 2015
- Claudin multigene family in channel catfish and their expression profiles in response to bacterial infection and hypoxia as revealed by meta-analysis of RNA-Seq datasets, Comparative Biochemistry and Physiology - Part D: Genomics and Proteomics, 2015
- Construction of a high-density, high-resolution genetic map and its integration with BAC-based physical map in channel catfish, DNA Research, 2015
- The cytochrome P450 genes of channel catfish: Their involvement in disease defense responses as revealed by meta-analysis of RNA-Seq data sets, BBA - General Subjects, 2014
- Development of the catfish 250K SNP array for genome-wide association studies, BMC Research Notes, 2014
- Identification and Analysis of Genome-Wide SNPs Provide Insight into Signatures of Selection and Domestication in Channel Catfish (Ictalurus punctatus), PLOS ONE, 2014
- Analysis of 52 Rab GTPases from channel catfish and their involvement in immune responses after bacterial infections, DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2014
- Pathogen recognition receptors in channel catfish: IV. Identification, phylogeny and expression analysis of peptidoglycan recognition proteins, DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2014
- Pathogen recognition receptors in channel catfish: III Phylogeny and expression analysis of Toll-like receptors, DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2013
- Identification of Cytochrome P450 (CYP) Genes in Zhikong Scallop (Chlamys farreri), 中国海洋大学学报：英文版, 2013
- Bulk segregant RNA-seq reveals expression and positional candidate genes and allele-specific expression for disease resistance against enteric septicemia of catfish, BMC GENOMICS, 2013
- RNA-Seq reveals expression signatures of genes involved in oxygen transport, protein synthesis, folding, and degradation in response to heat stress in catfish, PHYSIOLOGICAL GENOMICS, 2013
- Sixteen polymorphic microsatellite markers for the mud snail, Bullacta exarata (Philippi, 1848), CONSERVATION GENETICS RESOURCES, 2010
- Bioinformatics in Aquaculture: Principles and Methods, WILEY Blackwell, 2017
