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王元高
Life Science
中国科学院大学
上海
Language: 中文, 英文
染色体外环状Dna
染色体
Dna
环状Dna
基因组学
免疫系统
应激反应
调控
生物过程
研究
Areas of Focus
- 染色体外环状DNA
- 损伤应激对免疫系统的调控
Work Experience
- 2017-10~2023-01 - 哈佛医学院波士顿儿童医院 - 博士后
- 2015-08~2017-09 - 中科院上海生命科学学院 - 研究助理
- 2008-09~2015-07 - 中科院上海生命科学学院 - 理学博士
- 2004-09~2008-07 - 武汉大学生命科学学院 - 理学学士
Academic Background & Achievements
- 2008-09--2015-07 理学博士: 中科院上海生命科学学院
- 2004-09--2008-07 理学学士: 武汉大学生命科学学院
Publications
- Purification, full-length sequencing and genomic origin mapping of eccDNA, 王元高, 2022
- eccDNAs are apoptotic products with high innate immunostimulatory activity, 王元高, 2021
- Inhibition of CK1 potentiates the therapeutic efficacy of CDK4/6 inhibitor in breast cancer, 王元高, 2021
- Quantitative integration of epigenomic variation and transcription factor binding using MAmotif toolkit identifies an important role of IRF2 as transcription activator at gene promoters, 王元高, 2018
- Hemin Improves Insulin Sensitivity and Lipid Metabolism in Cultured Hepatocytes and Mice Fed a High-Fat Diet, 王元高, 2017
- CLOCK and BMAL1 Regulate Muscle Insulin Sensitivity via SIRT1 in Male Mice, 王元高, 2016
- Down-regulation of risa improves insulin sensitivity by enhancing autophagy, 王元高, 2016
- CLOCK/BMAL1 regulates circadian change of mouse hepatic insulin sensitivity by SIRT1, 王元高, 2014
- A High-Throughput Quantitative Approach Reveals More Small RNA Modifications in Mouse Liver and Their Correlation with Diabetes, 王元高, 2013
- Amyloid-β Induces Hepatic Insulin Resistance In Vivo via JAK2, 王元高, 2013
Awards
- 哈佛医学院中国科学家与学者协会杰出研究奖 (2022)
