Professor | 王元高 | 数字化转型顾问

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Name

王元高

Contact Information

ygwang@sinh.ac.cn

Language ability

中文, 英文

Province

上海

University/Lab Affiliation and Title	中国科学院大学
Faculty	Life Sciences
Academic Background & Achievements	2008-09--2015-07 理学博士: 中科院上海生命科学学院 2004-09--2008-07 理学学士: 武汉大学生命科学学院
Work Experience	2017-10~2023-01 - 哈佛医学院波士顿儿童医院 - 博士后 2015-08~2017-09 - 中科院上海生命科学学院 - 研究助理 2008-09~2015-07 - 中科院上海生命科学学院 - 理学博士 2004-09~2008-07 - 武汉大学生命科学学院 - 理学学士
Awards	哈佛医学院中国科学家与学者协会杰出研究奖 (2022)

University/Lab Affiliation and Title

中国科学院大学

Faculty

Life Sciences

Academic Background & Achievements

Work Experience

Awards

Areas of Focus	染色体外环状DNA 损伤应激对免疫系统的调控
Publications	Purification, full-length sequencing and genomic origin mapping of eccDNA, 王元高, 2022 eccDNAs are apoptotic products with high innate immunostimulatory activity, 王元高, 2021 Inhibition of CK1 potentiates the therapeutic efficacy of CDK4/6 inhibitor in breast cancer, 王元高, 2021 Quantitative integration of epigenomic variation and transcription factor binding using MAmotif toolkit identifies an important role of IRF2 as transcription activator at gene promoters, 王元高, 2018 Hemin Improves Insulin Sensitivity and Lipid Metabolism in Cultured Hepatocytes and Mice Fed a High-Fat Diet, 王元高, 2017 CLOCK and BMAL1 Regulate Muscle Insulin Sensitivity via SIRT1 in Male Mice, 王元高, 2016 Down-regulation of risa improves insulin sensitivity by enhancing autophagy, 王元高, 2016 CLOCK/BMAL1 regulates circadian change of mouse hepatic insulin sensitivity by SIRT1, 王元高, 2014 A High-Throughput Quantitative Approach Reveals More Small RNA Modifications in Mouse Liver and Their Correlation with Diabetes, 王元高, 2013 Amyloid-β Induces Hepatic Insulin Resistance In Vivo via JAK2, 王元高, 2013

Areas of Focus

染色体外环状DNA
损伤应激对免疫系统的调控

Publications

Purification, full-length sequencing and genomic origin mapping of eccDNA, 王元高, 2022
eccDNAs are apoptotic products with high innate immunostimulatory activity, 王元高, 2021
Inhibition of CK1 potentiates the therapeutic efficacy of CDK4/6 inhibitor in breast cancer, 王元高, 2021
Quantitative integration of epigenomic variation and transcription factor binding using MAmotif toolkit identifies an important role of IRF2 as transcription activator at gene promoters, 王元高, 2018
Hemin Improves Insulin Sensitivity and Lipid Metabolism in Cultured Hepatocytes and Mice Fed a High-Fat Diet, 王元高, 2017
CLOCK and BMAL1 Regulate Muscle Insulin Sensitivity via SIRT1 in Male Mice, 王元高, 2016
Down-regulation of risa improves insulin sensitivity by enhancing autophagy, 王元高, 2016
CLOCK/BMAL1 regulates circadian change of mouse hepatic insulin sensitivity by SIRT1, 王元高, 2014
A High-Throughput Quantitative Approach Reveals More Small RNA Modifications in Mouse Liver and Their Correlation with Diabetes, 王元高, 2013
Amyloid-β Induces Hepatic Insulin Resistance In Vivo via JAK2, 王元高, 2013

染色体外环状Dna 染色体 Dna 环状Dna 基因组学免疫系统应激反应调控生物过程研究

周晓艺 - 上海师范大学

潘乾 - 中南大学

Area of Focus
遗传学 | 医学 | Dna | 基因 | 克隆 | 研究 | 分子 | 生物学 | 遗传性 | 耳聋

陈春来 - 清华大学

Area of Focus
荧光 | 单分子 | 技术 | 蛋白 | Dna | 靶向 | 机制 | Crispr | 剪切 | 研究

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