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王四宝
Life Science
中国科学院大学
上海
Language: 中文, 英语
媒介昆虫
微生物
相互作用
微生物组学
表观遗传学
昆虫
遗传学
分子生物学
共生
病原体
Areas of Focus
- 媒介昆虫与微生物相互作用
- 昆虫微生物组学
- 昆虫表观遗传学
Work Experience
- 2020-05~现在 - 中国科学院分子植物科学卓越创新中心 - 研究员
- 2013-02~2020-04 - 中国科学院上海生命科学研究院植物生理生态所 - 研究员
- 2009-09~2013-02 - 美国约翰霍普金斯大学 - 博士后
- 2007-01~2009-08 - 美国马里兰大学 - 博士后
- 2000-07~2003-06 - 安徽农业大学 - 讲师、副教授
Academic Background & Achievements
- 2003-09--2006-12 博士: 中国科学院上海生命科学研究院
Publications
- The ASH1-PEX16 regulatory pathway controls peroxisome biogenesis for appressorium-mediated insect infection by a fungal pathogen, 第11作者, 2023
- Chemometrics and genome mining reveal an unprecedented family of sugar acid-containing fungal nonribosomal cyclodepsipeptides, 第9作者, 2022
- Expression of mosquito miRNAs in entomopathogenic fungus induces pathogen-mediated host RNA interference and increases fungal efficacy, 第11作者, 2022
- Regulatory Roles of Histone Modifications in Filamentous Fungal Pathogens, 第11作者, 2022
- Insects defend against fungal infection by employing microRNAs to silence virulence-related genes, 第11作者, 2021
- A natural symbiotic bacterium drives mosquito refractoriness to Plasmodium infection via secretion of an antimalarial lipase, 第11作者, 2021
- Clock genes and environmental cues coordinate Anopheles pheromone synthesis, swarming, and mating, 第11作者, 2021
- Genomic landscape and genetic manipulation of the black soldier fly Hermetia illucens, a natural waste recycler, 第17作者, 2020
- Mosquito Microbiota and Implications for Disease Control, 第11作者, 2020
- Coordinated regulation of infection-related morphogenesis by the KMT2-Cre1-Hyd4 regulatory pathway to facilitate fungal infection, 第11作者, 2020
- Use of Microbiota to Fight Mosquito-Borne Disease, 第2作者, 2020
- A fungal pathogen deploys a small RNA to attenuate mosquito immunity and facilitate infection, 第11作者, 2019
- A Gut Symbiotic Bacterium Serratia marcescens Renders Mosquito Resistance to Plasmodium Infection Through Activation of Mosquito Immune Responses, 第11作者, 2019
- Interaction of entomopathogenic fungi with the host immune system, 第11作者, 2018
- In vivo gene expression profiling of the entomopathogenic fungus Beauveria bassiana elucidates its infection stratagems in mosquito., 第11作者, 2017
- CRISPR/Cas9-mediated efficient genome editing via blastospore-based transformation in entomopathogenic fungus Beauveria bassiana, 第11作者, 2017
- Insect pathogenic fungus interacts with the gut microbiota to accelerate mosquito mortality, 第11作者, 2017
- Insect Pathogenic Fungi: Genomics, Molecular Interactions, and Genetic Improvements, 第2作者, 2017
- Driving mosquito refractoriness to Plasmodium falciparum with engineered symbiotic bacteria, 第11作者, 2017
- Transmission Risk from Imported Plasmodium vivax Malaria in the China-Myanmar Border Region, 第12作者, 2015
- Genetic control and paratransgenesis of mosquito-borne diseases, 第3作者, 2015
- Genome-wide analysis of DNA methylation in the sexual stage of the insect pathogenic fungus Cordyceps militaris, 第4
Awards
- 中国科学院优秀导师 (2022): 院级
- 真菌杀虫剂产业化及森林害虫持续控制技术二等奖 (2009): 国家级
- 真菌杀虫剂产业化及森林害虫持续控制技术的研究一等奖 (2008): 省级
- 虫草和近缘属及其无性型的物种多样性和遗传多样性的研究一等奖 (2006): 省级
