Professor | 赵双双 | 数字化转型顾问

Name

赵双双

Contact Information

sszhao2@siii.cas.cn

Language ability

英语, 中文

Province

上海

University/Lab Affiliation and Title	中国科学院大学
Faculty	Life Sciences
Academic Background & Achievements	2016-09--2018-05 联合培养博士生: 哈佛大学 2012-09--2018-07 博士: 北京协和医学院清华大学
Work Experience	2023-10~现在 - 中国科学院上海免疫与感染研究所 - 副研究员 2023-03~2023-09 - 中国科学院上海免疫与感染研究所 - 助理研究员 2019-07~2023-02 - 中国科学院上海巴斯德研究所（现上海免疫与感染研究所） - 博士后 2016-09~2018-05 - 哈佛大学 - 联合培养博士生 2012-09~2018-07 - 北京协和医学院清华大学 - 博士生

University/Lab Affiliation and Title

中国科学院大学

Faculty

Life Sciences

Academic Background & Achievements

Work Experience

Areas of Focus	病原宿主互作的细胞生物学及光学成像
Publications	Discovery of Trametinib as an orchestrater for cytoskeletal vimentin remodeling, 赵双双, 2024 Vimentin cage - A double-edged sword in host anti-infection defense, 赵双双, 2024 Salmonella effector SopB reorganizes cytoskeletal vimentin to maintain replication vacuoles for efficient infection, 赵双双, 2023 The diverse actions of cytoskeletal vimentin in bacterial infection and host defense., 赵双双, 2023 Host cytoskeletal vimentin serves as a structural organizer and an RNA-binding protein regulator to facilitate Zika viral replication, 赵双双, 2022 Multifaceted function of myosin-18, an unconventional class of the myosin superfamily., 赵双双, 2021 Different formins restrict localization of distinct tropomyosins on dorsal stress fibers in osteosarcoma cells, 赵双双, 2020 Hepatocyte mitochondria-derived danger signals directly activate hepatic stellate cells and drive progression of liver fibrosis., 赵双双, 2020 A novel biphenyl compound IMB-S7 ameliorates hepatic fibrosis in BDL rats by suppressing Sp1-mediated integrin αv expression., 赵双双, 2020 Myosin-18B promotes mechanosensitive CaMKK2-AMPK-VASP regulation of contractile actin stress fibers, 赵双双, 2020

Areas of Focus

病原宿主互作的细胞生物学及光学成像

Publications

Discovery of Trametinib as an orchestrater for cytoskeletal vimentin remodeling, 赵双双, 2024
Vimentin cage - A double-edged sword in host anti-infection defense, 赵双双, 2024
Salmonella effector SopB reorganizes cytoskeletal vimentin to maintain replication vacuoles for efficient infection, 赵双双, 2023
The diverse actions of cytoskeletal vimentin in bacterial infection and host defense., 赵双双, 2023
Host cytoskeletal vimentin serves as a structural organizer and an RNA-binding protein regulator to facilitate Zika viral replication, 赵双双, 2022
Multifaceted function of myosin-18, an unconventional class of the myosin superfamily., 赵双双, 2021
Different formins restrict localization of distinct tropomyosins on dorsal stress fibers in osteosarcoma cells, 赵双双, 2020
Hepatocyte mitochondria-derived danger signals directly activate hepatic stellate cells and drive progression of liver fibrosis., 赵双双, 2020
A novel biphenyl compound IMB-S7 ameliorates hepatic fibrosis in BDL rats by suppressing Sp1-mediated integrin αv expression., 赵双双, 2020
Myosin-18B promotes mechanosensitive CaMKK2-AMPK-VASP regulation of contractile actin stress fibers, 赵双双, 2020

病原体宿主细胞生物学光学成像感染防御细胞骨架波形蛋白沙门氏菌寨卡病毒

朱永群 - 浙江大学

Area of Focus
病原体 | 宿主 | 免疫 | 信号 | 蛋白质 | 机制 | 菌群 | 结构生物学 | 疾病 | 治疗

时津霞 - 上海师范大学

戴阿光 - 中国科学院大学

Area of Focus
细胞骨架 | 肌肉 | 细胞生物学 | 微生物学 | 生物物理学 | 冷冻电镜 | 病原体 | 宿主 | 互作 | 研究

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