Areas of Focus
- 肿瘤药理学
- 肿瘤代谢
- 肿瘤免疫
Work Experience
- 2013-01~现在 - 中国科学院上海药物研究所 - 研究员
- 2011-10~2012-12 - 中国科学院上海药物研究所 - 副研究员
- 2011-03~2011-09 - 中国科学院上海药物研究所 - 助理研究员
- 2008-01~2011-02 - 美国哈佛医学院Dana-Farber肿瘤研究所 - 博士后
Academic Background & Achievements
- 2002-09--2007-06 博士: 中国科学院上海药物研究所
- 1998-09--2002-06 本科: 中国药科大学
Publications
- Oncogenic KRAS induces arginine auxotrophy and confers a therapeutic vulnerability to SLC7A1 inhibition in non-small cell lung cancer, 黄敏, 2024
- Discovery of Novel Drug-like PHGDH Inhibitors to Disrupt Serine Biosynthesis for Cancer Therapy, 黄敏, 2023
- Global identification of phospho-dependent SCF substrates reveals a FBXO22 phosphodegron and an ERK-FBXO22-BAG3 axis in tumorigenesis, 黄敏, 2022
- Metabolic Regulation of CD8(+) T Cells: From Mechanism to Therapy, 黄敏, 2022
- NAMPT-targeting PROTAC promotes antitumor immunity via suppressing myeloid-derived suppressor cell expansion, 黄敏, 2022
- Making Protein Degradation Visible: Discovery of Theranostic PROTACs for Detecting and Degrading NAMPT, 黄敏, 2022
- SLC1A1-mediated cellular and mitochondrial influx of R-2-hydroxyglutarate in vascular endothelial cells promotes tumor angiogenesis in IDH1-mutant solid tumors, 黄敏, 2022
- Antitumor pharmacological research in the era of personalized medicine, 黄敏, 2022
- Discovery of Novel Pyrrolo2,3-dpyrimidine-based Derivatives as Potent JAK/HDAC Dual Inhibitors for the Treatment of Refractory Solid Tumors, 黄敏, 2022
- Discovery of Highly Potent Nicotinamide Phosphoribosyltransferase Degraders for Efficient Treatment of Ovarian Cancer, 黄敏, 2022
Awards
- 中国青年女科学家奖 (2023): 国家级
- 药明康德生命化学研究奖 (2017): 其他
- 上海市科技系统青年五四奖章 (2017): 省级
- 上海市巾帼创新新秀奖暨上海市“三八红旗手” (2016): 省级
- 施维雅青年药理学家奖 (2016): 其他
- 中源协和生命医学奖创新突破奖 (2016): 其他
- 中国科学院卢嘉锡青年人才奖 (2013): 部委级
