Areas of Focus
- 基于纳米技术的肿瘤靶向药物输送
Work Experience
- 2020-10~现在 - 中国科学院上海药物研究所 - 研究员
- 2014-10~2020-09 - 中国科学院上海药物研究所 - 副研究员
- 2012-07~2014-09 - 中国科学院上海药物研究所 - 助理研究员
- 2007-09~2012-06 - 中国科学院上海药物研究所 - 理学博士
Academic Background & Achievements
- 2007-09--2012-06 理学博士: 中国科学院上海药物研究所
Publications
- Co-delivering irinotecan and imiquimod by pH-responsive micelle amplifies anti-tumor immunity against colorectal cancer, 尹琦, 2023
- Promote intratumoral drug release and penetration to counteract docetaxel-induced metastasis by photosensitizer-modified red blood cell membrane-coated nanoparticle, 尹琦, 2023
- Combining gut microbiota modulation and chemotherapy by capecitabine-loaded prebiotic nanoparticle improves colorectal cancer therapy, 尹琦, 2023
- Breaking tumor immunosuppressive network by regulating multiple nodes with triadic drug delivery nanoparticles, 尹琦, 2023
- Nanosized drug delivery systems modulating immunosuppressive microenvironment for improving cancer immunotherapy, 尹琦, 2022
- Anti-hypoxia nanosized drug delivery systems improving cancer therapy, 尹琦, 2022
- Nano drug delivery systems improve metastatic breast cancer therapy, 尹琦, 2021
- Gut microbiota: influence on carcinogenesis and modulation strategies by drug delivery systems to improve cancer therapy, 尹琦, 2021
- Ternary regulation of tumor microenvironment by heparanase-sensitive micelle-loaded monocytes improves chemo-immunotherapy of metastatic breast cancer, 尹琦, 2021
- Calcitriol-loaded dual-pH-sensitive micelle counteracts pro-metastasis effect of paclitaxel in triple-negative breast cancer therapy, 尹琦, 2020
- Tumor microenvironment-responsive docetaxel-loaded micelle combats metastatic breast cancer, 尹琦, 2019
- In vivo environment-adaptive nanocomplex with tumor cell-specific cytotoxicity enhances T cells infiltration and improves cancer therapy, 尹琦, 2019
- Cocktail strategy based on spatio-temporally controlled nano device improves therapy of breast cancer, 尹琦, 2019
Awards
- 一等奖 (2023): 提高难溶性药物体内递送效率的制剂关键技术及应用
- 二等奖 (2020): 新型纳米载药系统克服肿瘤化疗耐药的应用基础研究
- 一等奖 (2020): 提高难溶性药物疗效与候选药物成药性的载药系统研究
- 度赛诺菲-上海生科院优秀青年人才奖 (2019)
- 一等奖 (2015): 中国药学会科学技术奖
- 一等奖 (2013): 上海药学科技奖
