Areas of Focus
- 发育遗传与干细胞生物学
Work Experience
- 2000-2009: 辛辛那提大学儿童医院医学中心助理教授、副教授、教授
- 2009-2016: 中国科学院动物研究所研究员、膜生物学国家重点实验室主任
- 2016至今: 复旦大学教授,生命科学学院院长
Academic Background & Achievements
- 1980-1984: 杭州大学(现浙江大学)生物系学士学位
- 1984-1987: 中国科学院上海细胞生物学研究所硕士学位
- 1990-1995: 美国圣路易斯华盛顿大学博士学位
- 1995-2000: 美国哈佛医学院博士后研究
- 在Cell、Nature、Nat Cell Biol、Dev Cell、Cell Res、Nat Commun、J Clin Invest等杂志发表研究论文80多篇
Publications
- Znhit1 controls meiotic initiation in male germ cells by coordinating with Stra8 to activate meiotic gene expression, Sun S, Jiang Y, Zhang Q, Pan H, Li X, Yang L, Huang M, Wei W, Wang X, Qiu M, Cao L, He H, Yu M, Liu H, Zhao B, Jiang N, Li R, Lin X, 2022
- Modeling human thyroid development by fetal tissue-derived organoid culture, Liang J, Qian J, Yang L, Chen X, Wang X, Lin X, Wang X, Zhao B, 2022
- Recapitulation of SARS-CoV-2 infection and cholangiocyte damage with human liver ductal organoids, Zhao B, Ni C, Gao R, Wang Y, Yang L, Wei J, Lv T, Liang J, Zhang Q, Xu W, Xie Y, Wang X, Yuan Z, Liang J, Zhang R, Lin X, 2020
- Znhit1 controls intestinal stem cell maintenance by regulating H2A.Z incorporation, Zhao B, Chen Y, Jiang N, Yang L, Sun S, Zhang Y, Wen Z, Ray L, Liu H, Hou G, Lin X, 2019
- EMC3 coordinates surfactant protein and lipid homeostasis required for respiration, Tang X, Snowball M, Xu Y, Na C, Weaver T, Clair G, Kyle J, Zink E, Ansong C, Wei W, Huang M, Lin X, Whitsett J, 2017
- Epithelial heparan sulfate regulates Sonic Hedgehog signaling in lung development, He H, Huang M, Sun S, Wu Y, Lin X, 2017
- Trachea-derived Dpp controls adult midgut homeostasis in Drosophila, Li Z, Zhang Y, Han L, Shi L, Lin X, 2013
- SNX3 controls Wingless/Wnt secretion through regulating retromer-dependent recycling of Wntless, Zhang P, Wu Y, Belenkaya T, Lin X, 2011
- The Core Protein of Glypican Dally-Like Determines Its Biphasic Activity in Wingless Morphogen Signaling, Yan D, Wu Y, Feng Y, Lin S, Lin X, 2009
- The Retromer Complex Influences Wnt Secretion by Recycling Wntless from Endosomes to the Trans-Golgi Network, Belenkaya T, Wu Y, Tang X, Zhou B, Cheng L, Sharma Y, Yan D, Selva E, Lin X, 2008
- DrosophilaDpp morphogen movement is independent of dynamin-mediated endocytosis and is controlled by glypican members of heparan sulfate proteoglycans, Belenkaya T, Han C, Yan D, Opoka R, Khodoun M, Liu H, Lin X, 2004
- Dally cooperates with DrosophilaFrizzled 2 to transduce Wingless signalling, Lin X, Perrimon N, 1999
Awards
- 2010: 国家重大科学研究计划(973)首席科学家
- 2007-2011: 美国癌症协会学者奖
- 2007: 国家自然科学基金委海外杰出青年科学家奖 (B类)
- 2005: 浙江大学荣誉教授
- 2005-2008: 美国畸形儿基金会科研奖
- 2002-2004: Basil O’Connor畸形儿基金会学者奖
- 2001-2003: 俄亥俄州癌症研究奖
- 1997-2000: 美国陆军乳腺癌研究博士后奖学金
- 1999: 日本第十五届复合糖国际研讨会青年科学家奖
- 1995-1997: 霍华德休斯医学研究院博士后奖学金奖
- 1998: 上海细胞生物学研究所优秀科研奖