李晓菲
Life Science
上海交通大学
上海
Language: 中文, 英语
Contact
炎症 慢性疾病 免疫细胞 组织稳态 表观遗传学 造血干细胞 训练免疫 病原体 免疫反应 治疗策略
Areas of Focus
  • 慢性炎症致病及消退机制的研究
  • 慢性合并症的致病机制及治疗策略的研究
  • 造血干细胞训练免疫的表观遗传调控机制研究
Work Experience
  • 2022-至今: 上海交通大学生命科学技术学院,遗传与发育科学系,长聘教轨副教授
  • 2015-2021: 宾夕法尼亚大学转化医学系,免疫学和干细胞生物学,博士后
Academic Background & Achievements
  • 2010-2015: 复旦大学基础医学院,病原生物学,理学博士
  • 2006-2010: 河南大学生命科学学院,生物科学,理学学士
Publications
  • Maladaptive innate immune training of myelopoiesis links inflammatory comorbidities, Xiaofei Li, Hui Wang, Xiang Yu, Gundappa Saha, Lydia Kalafati, Charalampos Ioannidis, Ioannis Mitroulis, Mihai G Netea, Triantafyllos Chavakis, George Hajishengallis, 2022
  • DEL-1 promotes macrophage efferocytosis and clearance of inflammation, Ioannis Kourtzelis, Xiaofei Li, Ioannis Mitroulis, Daniel Grosser, Tetsuhiro Kajikawa, Baomei Wang, Michal Grzybek, Janusz Von Renesse, Aleksander Czogalla, Maria Troullinaki, Anaisa Ferreira, Christian Doreth, Klara Ruppova, Lan-Sun Chen, Kavita Hosur, Jong-Hyung Lim, Kyoung-Jin Chung, Sylvia Grossklaus, Anne Kathrin Tausche, Leo AB Joosten, Niki M Moutsopoulos, Ben Wielockx, Antonio Castrillo, Jonathan M Korostoff, Ünal Coskun, George Hajishengallis, Triantafyllos Chavakis, 2019
  • The DEL-1/β3 integrin axis promotes regulatory T cell responses during inflammation resolution, Xiaofei Li, Alessandra Colamatteo, Lydia Kalafati, Tetsuhiro Kajikawa, Hui Wang, Jong-Hyung Lim, Khalil Bdeir, Kyoung-Jin Chung, Xiang Yu, Clorinda Fusco, Antonio Porcellini, Salvatore De Simone, Giuseppe Matarese, Triantafyllos Chavakis, Veronica De Rosa, George Hajishengallis, 2020
  • Immunometabolic control of hematopoiesis, George Hajishengallis, Xiaofei Li, Triantafyllos Chavakis, 2021
  • Innate immune training of granulopoiesis promotes anti-tumor activity, Lydia Kalafati, Ioannis Kourtzelis, Jonas Schulte-Schrepping, Xiaofei Li, Aikaterini Hatzioannou, Tatyana Grinenko, Eman Hagag, Anupam Sinha, Canan Has, Sevina Dietz, Antonio Miguel de Jesus Domingues, Marina Nati, Sundary Sormendi, Ales Neuwirth, Antonios Chatzigeorgiou, Athanasios Ziogas, Mathias Lesche, Andreas Dahl, Ian Henry, Pallavi Subramanian, Ben Wielockx, Peter Murray, Peter Mirtschink, Kyoung-Jin Chung, Joachim L Schultze, Mihai G Netea, George Hajishengallis, Panayotis Verginis, Ioannis Mitroulis, Triantafyllos Chavakis, 2020
  • Stromal cell–derived DEL-1 inhibits Tfh cell activation and inflammatory arthritis, Hui Wang, Xiaofei Li, Tetsuhiro Kajikawa, Jieun Shin, Jong-Hyung Lim, Ioannis Kourtzelis, Kosuke Nagai, Jonathan M Korostoff, Sylvia Grossklaus, Ronald Naumann, Triantafyllos Chavakis, George Hajishengallis, 2021
  • The secreted protein DEL-1 activates a β3 integrin–FAK–ERK1/2–RUNX2 pathway and promotes osteogenic differentiation and bone regeneration, Da-Yo Yuh, Tomoki Maekawa, Xiaofei Li, Tetsuhiro Kajikawa, Khalil Bdeir, Triantafyllos Chavakis, George Hajishengallis, 2020
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