Professor | 赵凤东 | 数字化转型顾问

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Name	赵凤东
Contact Information	zhaodong68@hotmail.com
Language ability	英语, 中文
Province	浙江

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Name

赵凤东

Contact Information

zhaodong68@hotmail.com

Language ability

英语, 中文

Province

浙江

University/Lab Affiliation and Title	浙江大学
Faculty	Medical
Academic Background & Achievements	2003-2004: 英国布里斯托大学学习 2015-2016: 美国加州大学戴维斯分校学习获得5项国家自然科学基金资助发表了40余篇SCI论文
Awards	ISSLS年会最佳讨论者（2017）浙江省科学技术进步奖一等奖（2016）浙江省医药卫生科技奖一等奖（2016）浙江省科学技术进步奖二等奖（2010）

University/Lab Affiliation and Title

浙江大学

Faculty

Medical

Academic Background & Achievements

2003-2004: 英国布里斯托大学学习
2015-2016: 美国加州大学戴维斯分校学习
获得5项国家自然科学基金资助
发表了40余篇SCI论文

Awards

ISSLS年会最佳讨论者（2017）
浙江省科学技术进步奖一等奖（2016）
浙江省医药卫生科技奖一等奖（2016）
浙江省科学技术进步奖二等奖（2010）

Areas of Focus	椎间盘退变脊柱生物力学骨代谢
Publications	Site-1 protease controls osteoclastogenesis by mediating LC3 transcription, Zeyu Zheng, Xuyang Zhang, Bao Huang, Junhui Liu, Xiaoan Wei, Zhi Shan, Hao Wu, Zhenghua Feng, Yilei Chen, Shunwu Fan, Fengdong Zhao, Jian Chen, 2021 Homocysteine induces oxidative stress and ferroptosis of nucleus pulposus via enhancing methylation of GPX4, Xuyang Zhang, Zhaobo Huang, Ziang Xie, Yilei Chen, Zeyu Zheng, Xiao'an Wei, Bao Huang, Zhi Shan, Junhui Liu, Shunwu Fan, Jian Chen, Fengdong Zhao, 2020 The RCAN1.4-calcineurin/NFAT signaling pathway is essential for hypoxic adaption of intervertebral discs, Bao Huang, Yongqing He, Shengwen Li, Xiaoan Wei, Junhui Liu, Zhi Shan, Yue Huang, Jian Chen, Fengdong Zhao, 2020 Damage to the human lumbar cartilage endplate and its clinical implications, Bao Huang, Junhui Liu, Xiaoan Wei, Shengwen Li, Yufeng Xiang, Hao Wu, Jian Chen, Fengdong Zhao, 2020 IL-6/YAP1/ beta-catenin signaling is involved in intervertebral disc degeneration, Chen Jian, Mei Zhengfeng, Huang Bao, Zhang Xuyang, Liu Junhui, ShanZhi, Wang Jiasheng, Wang Xianjun, Zhao Fengdong, 2019 Via Administration of SB239063 Ameliorates Ovariectomy-Induced Bone Loss Suppressing Osteoclastogenesis in Mice, Bao Huang, Jiasheng Wang, Xuyang Zhang, Ziang Xie, Hao Wu, Junhui Liu, Zhiwei Jie, Xiangde Zhao, An Qin, Shunwu Fan, Jian Chen, Fengdong Zhao, 2019 Obesity Mediates Apoptosis and Extracellular Matrix Metabolic Imbalances via MAPK Pathway Activation in Intervertebral Disk Degeneration, Xuyang Zhang, Jian Chen, Bao Huang, Jiasheng Wang, Zhi Shan, Junhui Liu, Yilei Chen, Shengyun Li, Shunwu Fan, Fengdong Zhao, 2019 Alpha 2-Macroglobulin as Dual Regulator for Both Anabolism and Catabolism in the Cartilaginous Endplate of Intervertebral Disc, Huang Bao, Chen Jian, Zhang Xuyang, Wang Jiasheng, Zheng Zeyu, Shan Zhi, Liu Junhui, Zhu Zhihai, Zhao Fengdong, 2018 Association between Modic changes and endplate sclerosis: Evidence from a clinical radiology study and a rabbit model, Liu J, Huang B, Hao L, Shan Z, Zhang X, Chen J, Fan S, Zhao F, 2018 Mechanism of formation of intravertebral clefts in osteoporotic vertebral compression fractures: An in vitro biomechanical study, Chongyan W, Zhang X, Li S, Liu J, Shan Z, Wang J, Chen J, Fan S, Zhao F, 2018 Superior cortical screw in osteoporotic lumbar vertebrae: A biomechanics and microstructure-based study, Yu T, Zhang X, Liu J, Li S, Shan Z, Fan S, Zhao F, 2018 The mechanism of thoracolumbar burst fracture may be related to the basivertebral foramen, Zhang X, Li S, Zhao X, Christiansen BA, Chen J, Fan S, Zhao F, 2018 Accuracy of pedicle screw placement in posterior lumbosacral instrumentation by computer tomography evaluation: A multi-centric retrospective clinical study, Yu T, Mi S, He Y, Zhang Z, Dai W, Tian J, Hong Z, Fan S, Zhao F, 2017 Propionibacterium Acnes Incubation in the Discs Can Result in Time-Dependent Modic Changes: A Long Term Rabbit Model, Shan Z, Zhang X, Li S, Yu T, Liu J, Zhao F, 2017 The Influence of Direct Inoculation of Propionibacterium acnes on Modic Changes in the Spine: Evidence from a Rabbit Model, Shan Z, Zhang X, Li S, Yu T, Mamuti M, Zhao F, 2017 Comparison of pedicle fixation by the Wiltse approach and the conventional posterior open approach for thoracolumbar fractures, using MRI, histological and electrophysiological analyses of the multifidus muscle, Junhui L, Zhengbao P, Wenbin X, Lu H, Shengyun L, Shunwu F,

Areas of Focus

椎间盘退变
脊柱生物力学
骨代谢

Publications

Site-1 protease controls osteoclastogenesis by mediating LC3 transcription, Zeyu Zheng, Xuyang Zhang, Bao Huang, Junhui Liu, Xiaoan Wei, Zhi Shan, Hao Wu, Zhenghua Feng, Yilei Chen, Shunwu Fan, Fengdong Zhao, Jian Chen, 2021
Homocysteine induces oxidative stress and ferroptosis of nucleus pulposus via enhancing methylation of GPX4, Xuyang Zhang, Zhaobo Huang, Ziang Xie, Yilei Chen, Zeyu Zheng, Xiao'an Wei, Bao Huang, Zhi Shan, Junhui Liu, Shunwu Fan, Jian Chen, Fengdong Zhao, 2020
The RCAN1.4-calcineurin/NFAT signaling pathway is essential for hypoxic adaption of intervertebral discs, Bao Huang, Yongqing He, Shengwen Li, Xiaoan Wei, Junhui Liu, Zhi Shan, Yue Huang, Jian Chen, Fengdong Zhao, 2020
Damage to the human lumbar cartilage endplate and its clinical implications, Bao Huang, Junhui Liu, Xiaoan Wei, Shengwen Li, Yufeng Xiang, Hao Wu, Jian Chen, Fengdong Zhao, 2020
IL-6/YAP1/ beta-catenin signaling is involved in intervertebral disc degeneration, Chen Jian, Mei Zhengfeng, Huang Bao, Zhang Xuyang, Liu Junhui, ShanZhi, Wang Jiasheng, Wang Xianjun, Zhao Fengdong, 2019
Via Administration of SB239063 Ameliorates Ovariectomy-Induced Bone Loss Suppressing Osteoclastogenesis in Mice, Bao Huang, Jiasheng Wang, Xuyang Zhang, Ziang Xie, Hao Wu, Junhui Liu, Zhiwei Jie, Xiangde Zhao, An Qin, Shunwu Fan, Jian Chen, Fengdong Zhao, 2019
Obesity Mediates Apoptosis and Extracellular Matrix Metabolic Imbalances via MAPK Pathway Activation in Intervertebral Disk Degeneration, Xuyang Zhang, Jian Chen, Bao Huang, Jiasheng Wang, Zhi Shan, Junhui Liu, Yilei Chen, Shengyun Li, Shunwu Fan, Fengdong Zhao, 2019
Alpha 2-Macroglobulin as Dual Regulator for Both Anabolism and Catabolism in the Cartilaginous Endplate of Intervertebral Disc, Huang Bao, Chen Jian, Zhang Xuyang, Wang Jiasheng, Zheng Zeyu, Shan Zhi, Liu Junhui, Zhu Zhihai, Zhao Fengdong, 2018
Association between Modic changes and endplate sclerosis: Evidence from a clinical radiology study and a rabbit model, Liu J, Huang B, Hao L, Shan Z, Zhang X, Chen J, Fan S, Zhao F, 2018
Mechanism of formation of intravertebral clefts in osteoporotic vertebral compression fractures: An in vitro biomechanical study, Chongyan W, Zhang X, Li S, Liu J, Shan Z, Wang J, Chen J, Fan S, Zhao F, 2018
Superior cortical screw in osteoporotic lumbar vertebrae: A biomechanics and microstructure-based study, Yu T, Zhang X, Liu J, Li S, Shan Z, Fan S, Zhao F, 2018
The mechanism of thoracolumbar burst fracture may be related to the basivertebral foramen, Zhang X, Li S, Zhao X, Christiansen BA, Chen J, Fan S, Zhao F, 2018
Accuracy of pedicle screw placement in posterior lumbosacral instrumentation by computer tomography evaluation: A multi-centric retrospective clinical study, Yu T, Mi S, He Y, Zhang Z, Dai W, Tian J, Hong Z, Fan S, Zhao F, 2017
Propionibacterium Acnes Incubation in the Discs Can Result in Time-Dependent Modic Changes: A Long Term Rabbit Model, Shan Z, Zhang X, Li S, Yu T, Liu J, Zhao F, 2017
The Influence of Direct Inoculation of Propionibacterium acnes on Modic Changes in the Spine: Evidence from a Rabbit Model, Shan Z, Zhang X, Li S, Yu T, Mamuti M, Zhao F, 2017
Comparison of pedicle fixation by the Wiltse approach and the conventional posterior open approach for thoracolumbar fractures, using MRI, histological and electrophysiological analyses of the multifidus muscle, Junhui L, Zhengbao P, Wenbin X, Lu H, Shengyun L, Shunwu F,

椎间盘退变脊柱生物力学骨代谢病理生理分子机制免疫微环境研究

骆严 - 浙江大学

Area of Focus
肿瘤 | 生物化学 | 代谢 | 干细胞 | 伤口愈合 | 抗癌 | 药物开发 | 研究 | 机制 | 平台

周煜东 - 浙江大学

Area of Focus
神经发育 | 代谢 | 神经退行性 | 免疫激活 | 神经元 | 突触 | 环境因素 | 机制 | 研究 | 疾病

王猛 - 浙江大学

Area of Focus
线粒体 | Trna | 代谢 | 障碍 | 疾病 | 临床特征 | 遗传学 | 发育规律 | 致病机制 | 研究

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