Professor | 冯桂海 | 数字化转型顾问

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Name	冯桂海
Contact Information	fenggh@ioz.ac.cn
Language ability	中文, 英文
Province	北京

Upload Avatar (500 x 500)

Name

冯桂海

Contact Information

fenggh@ioz.ac.cn

Language ability

中文, 英文

Province

北京

University/Lab Affiliation and Title	中国科学院
Faculty	Institute of Zoology
Academic Background & Achievements	2007 - 生物科学学士学位: 山东大学（威海） 2010 - 生物安全硕士学位: 军事医学科学院（指导老师：王玉民） 2014 - 生物信息学博士学位: 中国科学院大学（指导老师：王秀杰）
Work Experience	2014-2018 - 博士后训练: 中国科学院动物研究所（合作导师：周琪） 2018-2023 - 副研究员: 中国科学院动物研究所 2024-至今 - 研究员: 中国科学院动物研究所

University/Lab Affiliation and Title

中国科学院

Faculty

Institute of Zoology

Academic Background & Achievements

2007 - 生物科学学士学位: 山东大学（威海）
2010 - 生物安全硕士学位: 军事医学科学院（指导老师：王玉民）
2014 - 生物信息学博士学位: 中国科学院大学（指导老师：王秀杰）

Work Experience

2014-2018 - 博士后训练: 中国科学院动物研究所（合作导师：周琪）
2018-2023 - 副研究员: 中国科学院动物研究所
2024-至今 - 研究员: 中国科学院动物研究所

Areas of Focus	基因表达剂量的控制机制研究基因表达剂量的人工智能建模
Publications	Deciphering the placental abnormalities associated with somatic cell nuclear transfer at single-nucleus resolution., Jiang L, Wang X, Wang L, Ma S, Ding Y, Liu C, Wang S, Shao X, Zhang Y, Li Z, Li W, Feng G, Zhou Q., 2023 Characterisation of X chromosome status of human extended pluripotent stem cells., Wang Y, Yang N, Sun W, Zhao C, Hu X, Lu S, Cao S, Wang N, Hai T, Feng G, An C, Wang H., 2023 Single-Cell Transcriptomics of Proliferative Phase Endometrium: Systems Analysis of Cell-Cell Communication Network Using CellChat., Fang Z, Tian Y, Sui C, Guo Y, Hu X, Lai Y, Liao Z, Li J, Feng G, Jin L, Qian K., 2022 A Uterus-Inspired Niche Drives Blastocyst Development to the Early Organogenesis., Gu Z#, Guo J#, Zhai J#, Feng G#, Wang X, Gao Z, Li K, Ji S, Wang L, Xu Y, Chen X, Wang Y, Guo S, Yang M, Li L, Han H, Jiang L, Wen Y, Wang L, Hao J, Li W, Wang S, Wang H, Gu Q., 2022 Pharmacological Perturbation of Mechanical Contractility Enables Robust Transdifferentiation of Human Fibroblasts into Neurons., He ZQ#, Li YH#, Feng GH#, Yuan XW#, Lu ZB#, Dai M, Hu YP, Zhang Y, Zhou Q, Li W., 2022 Influence of feeder cells on transcriptomic analysis of pluripotent stem cells., Wan H, Fu R, Tong M, Wang Y, Wang L, Wang S, Zhang Y, Li W, Wang XJ, Feng G., 2022 Transcriptome and DNA Methylation Profiles of Mouse Fetus and Placenta Generated by Round Spermatid Injection., Zhu H, Sun H, Yu D, Li T, Hai T, Liu C, Zhang Y, Chen Y, Dai X, Li Z, Li W, Liu R, Feng G, Zhou Q., 2021 Overcoming Autocrine FGF Signaling-Induced Heterogeneity in Naive Human ESCs Enables Modeling of Random X Chromosome Inactivation., An C#, Feng G#, Zhang J, Cao S, Wang Y, Wang N, Lu F, Zhou Q, Wang H., 2020 Overcoming Intrinsic H3K27me3 Imprinting Barriers Improves Post-implantation Development after Somatic Cell Nuclear Transfer., Wang LY#, Li ZK#, Wang LB#, Liu C#, Sun XH#, Feng GH#, Wang JQ, Li YF, Qiao LY, Nie H, Jiang LY, Sun H, Xie YL, Ma SN, Wan HF, Lu FL, Li W, Zhou Q., 2020 Rbm14 maintains the integrity of genomic DNA during early mouse embryogenesis via mediating alternative splicing., Li J#, Wang C#, Feng G#, Zhang L, Chen G, Sun H, Wang J, Zhang Y, Zhou Q, Li W., 2020 Asymmetric Expression of LincGET Biases Cell Fate in Two-Cell Mouse Embryos., Wang J#, Wang L#, Feng G#, Wang Y#, Li Y, Li X, Liu C, Jiao G, Huang C, Shi J, Zhou T, Chen Q, Liu Z, Li W, Zhou Q., 2018 Generation of Bimaternal and Bipaternal Mice from Hypomethylated Haploid ESCs with Imprinting Region Deletions., Li ZK#, Wang LY#, Wang LB#, Feng GH#, Yuan XW#, Liu C, Xu K, Li YH, Wan HF, Zhang Y, Li YF, Li X, Li W, Zhou Q, Hu BY., 2018 SIRT6 deficiency results in developmental retardation in cynomolgus monkeys., Zhang W#, Wan H#, Feng G#, Qu J#, Wang J, Jing Y, Ren R, Liu Z, Zhang L, Chen Z, Wang S, Zhao Y, Wang Z, Yuan Y, Zhou Q, Li W, Liu GH, Hu B., 2018 Rat embryonic stem cells produce fertile offspring through tetraploid complementation., Li TD#, Feng GH#, Li YF#, Wang M#, Mao JJ, Wang JQ, Li X, Wang XP, Qu B, Wang LY, Zhang XX, Wan HF, Cui TT, Wan C, Liu L, Zhao XY, Hu BY, Li W, Zhou Q., 2017 Mettl3-mediated m6A regulates spermatogonial differentiation and meiosis initiation., Xu K#, Yang Y#, Feng GH#, Sun BF#, Chen JQ#, Li YF, Chen YS, Zhang XX, Wang CX, Jiang LY, Liu C, Zhang ZY, Wang XJ, Zhou Q, Yang YG, Li W., 2017 Ubiquitously expressed genes participate in cell-specific functions via alternative promoter usage., Feng G#, Tong M#, Xia B#, Luo GZ, Wang M, Xie D, Wan H, Zhang Y, Zhou Q, Wang XJ., 2016 Birth of fertile bimaternal offspring following intracytoplasmic injection of parthenogenetic haploid embryonic stem cells., Li Z#, Wan H#, Feng G#, Wang L#, He Z, Wang Y, Wang XJ, Li W, Zhou Q, Hu B., 2016

Areas of Focus

基因表达剂量的控制机制研究
基因表达剂量的人工智能建模

Publications

Deciphering the placental abnormalities associated with somatic cell nuclear transfer at single-nucleus resolution., Jiang L, Wang X, Wang L, Ma S, Ding Y, Liu C, Wang S, Shao X, Zhang Y, Li Z, Li W, Feng G*, Zhou Q*., 2023
Characterisation of X chromosome status of human extended pluripotent stem cells., Wang Y, Yang N, Sun W, Zhao C, Hu X, Lu S, Cao S, Wang N, Hai T, Feng G*, An C*, Wang H*., 2023
Single-Cell Transcriptomics of Proliferative Phase Endometrium: Systems Analysis of Cell-Cell Communication Network Using CellChat., Fang Z, Tian Y, Sui C, Guo Y, Hu X, Lai Y, Liao Z, Li J, Feng G*, Jin L*, Qian K*., 2022
A Uterus-Inspired Niche Drives Blastocyst Development to the Early Organogenesis., Gu Z#, Guo J#, Zhai J#, Feng G#, Wang X, Gao Z, Li K, Ji S, Wang L, Xu Y, Chen X, Wang Y, Guo S, Yang M, Li L, Han H, Jiang L, Wen Y, Wang L, Hao J, Li W, Wang S, Wang H, Gu Q., 2022
Pharmacological Perturbation of Mechanical Contractility Enables Robust Transdifferentiation of Human Fibroblasts into Neurons., He ZQ#, Li YH#, Feng GH#, Yuan XW#, Lu ZB#, Dai M, Hu YP, Zhang Y, Zhou Q, Li W., 2022
Influence of feeder cells on transcriptomic analysis of pluripotent stem cells., Wan H, Fu R, Tong M, Wang Y, Wang L, Wang S, Zhang Y, Li W, Wang XJ, Feng G*., 2022
Transcriptome and DNA Methylation Profiles of Mouse Fetus and Placenta Generated by Round Spermatid Injection., Zhu H, Sun H, Yu D, Li T, Hai T, Liu C, Zhang Y, Chen Y, Dai X, Li Z, Li W, Liu R*, Feng G*, Zhou Q*., 2021
Overcoming Autocrine FGF Signaling-Induced Heterogeneity in Naive Human ESCs Enables Modeling of Random X Chromosome Inactivation., An C#, Feng G#, Zhang J, Cao S, Wang Y, Wang N, Lu F, Zhou Q, Wang H., 2020
Overcoming Intrinsic H3K27me3 Imprinting Barriers Improves Post-implantation Development after Somatic Cell Nuclear Transfer., Wang LY#, Li ZK#, Wang LB#, Liu C#, Sun XH#, Feng GH#, Wang JQ, Li YF, Qiao LY, Nie H, Jiang LY, Sun H, Xie YL, Ma SN, Wan HF, Lu FL, Li W, Zhou Q., 2020
Rbm14 maintains the integrity of genomic DNA during early mouse embryogenesis via mediating alternative splicing., Li J#, Wang C#, Feng G#, Zhang L, Chen G, Sun H, Wang J, Zhang Y, Zhou Q, Li W., 2020
Asymmetric Expression of LincGET Biases Cell Fate in Two-Cell Mouse Embryos., Wang J#, Wang L#, Feng G#, Wang Y#, Li Y, Li X, Liu C, Jiao G, Huang C, Shi J, Zhou T, Chen Q, Liu Z, Li W, Zhou Q., 2018
Generation of Bimaternal and Bipaternal Mice from Hypomethylated Haploid ESCs with Imprinting Region Deletions., Li ZK#, Wang LY#, Wang LB#, Feng GH#, Yuan XW#, Liu C, Xu K, Li YH, Wan HF, Zhang Y, Li YF, Li X, Li W, Zhou Q, Hu BY., 2018
SIRT6 deficiency results in developmental retardation in cynomolgus monkeys., Zhang W#, Wan H#, Feng G#, Qu J#, Wang J, Jing Y, Ren R, Liu Z, Zhang L, Chen Z, Wang S, Zhao Y, Wang Z, Yuan Y, Zhou Q, Li W, Liu GH, Hu B., 2018
Rat embryonic stem cells produce fertile offspring through tetraploid complementation., Li TD#, Feng GH#, Li YF#, Wang M#, Mao JJ, Wang JQ, Li X, Wang XP, Qu B, Wang LY, Zhang XX, Wan HF, Cui TT, Wan C, Liu L, Zhao XY, Hu BY, Li W, Zhou Q., 2017
Mettl3-mediated m6A regulates spermatogonial differentiation and meiosis initiation., Xu K#, Yang Y#, Feng GH#, Sun BF#, Chen JQ#, Li YF, Chen YS, Zhang XX, Wang CX, Jiang LY, Liu C, Zhang ZY, Wang XJ, Zhou Q, Yang YG, Li W., 2017
Ubiquitously expressed genes participate in cell-specific functions via alternative promoter usage., Feng G#, Tong M#, Xia B#, Luo GZ, Wang M, Xie D, Wan H, Zhang Y, Zhou Q, Wang XJ., 2016
Birth of fertile bimaternal offspring following intracytoplasmic injection of parthenogenetic haploid embryonic stem cells., Li Z#, Wan H#, Feng G#, Wang L#, He Z, Wang Y, Wang XJ, Li W, Zhou Q, Hu B., 2016

基因表达剂量控制表观遗传学基因组学转录翻译建模细胞功能人工细胞组学分析

康乐 - 中国科学院

谭薇琦 - 中国科学院

张映 - 中国科学院

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