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冷启彬
Basic Medical Sciences
广州医科大学
广东
Language: 中文, 英语
肺癌
T细胞
免疫应答
肿瘤抗原
疫苗开发
微环境
分子机制
细胞机制
自身免疫病
免疫治疗
Areas of Focus
- 肺癌
- 肿瘤抗原特异性T细胞免疫应答
- 肿瘤微环境相互作用
- 肿瘤和自身免疫病的T细胞应答
Publications
- Siglec-9 acts as an immune checkpoint molecule on macrophages in glioblastoma, restricting T cell priming and immunotherapy response., Mei Y, Wang XM, Zhang J, Liu D, He JJ, Huang CL, Liao J, Wang YZ, Feng YY, Li HY, Liu XY, Chen LD, Yi W, Chen X, Bai HM, Liang ZG, Qiu L, Hui Y, Zhang QL, Leng Q, Chen J, Jia GS, 2023
- Single-Cell Analyses Reveal Mechanisms of Cancer Stem Cell Maintenance and Epithelial-Mesenchymal Transition in Recurrent Bladder Cancer., Wang H, Mei Y, Luo C, Huang Q, Wang Z, Lu GM, Qin L, Sun Z, Huang CW, Yang ZW, Chen J, Yin W, Qian CN, Zeng J, Chen L, Leng Q, Guo Y, Jia G, 2021
- Pre-existing heterologous T-cell immunity and neoantigen immunogenicity., Leng Q, Tarbe M, Long Q, Wang F, 2020
- NCoR1 restrains thymic negative selection by repressing Bim expression to spare thymocytes undergoing positive selection., Wang J, He N, Zhang N, Quan D, Zhang S, Zhang C, Yu RT, Atkins AR, Zhu R, Yang C, Cui Y, Liddle C, Downes M, Xiao H, Zheng Y, Auwerx J, Evans RM, Leng Q, 2017
- TLR3 signaling in macrophages is indispensable for the protective immunity of invariant natural killer T cells against enterovirus 71 infection., Zhu K, Yang J, Luo K, Zhang N, Yang CH, Chen J, Xu B, Guo NN, Wang J, Cui Y, Wang Y, Deng C, Qin C, Ge B, Hao S, Yang CF, Leng Q, 2015
Awards
- 2009: 中国科学院“百人计划”特聘教授
- 2010: 中国科学院上海生命科学研究院-Sinofi Aventis 优秀青年奖
- 2015: 中国科学院“朱李月华”优秀教师奖
