Areas of Focus
- 基于人工智能的靶向药物（主要是多肽）开发
- 基于人工智能的药物分析方法开发
Work Experience
- 目前 - 海军军医大学讲师
- 2016年 - 匹兹堡大学访问学者
Academic Background & Achievements
- 2017年 - 药物分析博士学位：海军军医大学（原第二军医大学），师从柴逸峰教授
- 科研经费近200万元
Publications
- Multimodal data fusion for supervised learning-based identification of USP7 inhibitors: a systematic comparison, Shen, Wen-Feng; Tang, He-Wei; Li, Jia-Bo; Li, Xiang; Chen, Si, 2023
- Lipophilic Constituents in Salvia miltiorrhiza Inhibit Activation of the Hepatic Stellate Cells by Suppressing the JAK1/STAT3 Signaling Pathway: A Network Pharmacology Study and Experimental Validation, Tang, Ya-Xin; Liu, Mingming; Liu, Long; Zhen, Bo-Rui; Wang, Tian-Tian; Li, Na; Lv, Nanning; Zhu, Zhenyu; Sun, Guoquan; Wang, Xiaobo; Chen, Si, 2022
- Design of stapled peptide-based PROTACs for MDM2 / MDMX atypical degradation and tumor suppression, Chen, Si; Li, Xiang; Li, Yinghua; Yuan, Xing; Geng, Chenchen; Gao, Songyan; Li, Jinyang; Ma, Bohan; Wang, Zhe; Lu, Wuyuan; Hu, Honggang, 2022
- Stapled Helical Peptides Bearing Different Anchoring Residues, Li, Xiang; Chen, Si; Zhang, Wei Dong; Hu, Hong Gang, 2020
- Discovery of Novel Ligands for TNF-alpha and TNF Receptor-1 through Structure-Based Virtual Screening and Biological Assay, Chen, Si; Feng, Zhiwei; Wang, Yun; Ma, Shifan; Hu, Ziheng; Yang, Peng; Chai, Yifeng; Xie, Xiangqun, 2017
