Professor | 邹美娟 | 数字化转型顾问

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Name	邹美娟
Contact Information	zoumeijuan@njmu.edu.cn
Language ability	中文, 英语
Province	江苏

Upload Avatar (500 x 500)

Name

邹美娟

Contact Information

zoumeijuan@njmu.edu.cn

Language ability

中文, 英语

Province

江苏

University/Lab Affiliation and Title	南京医科大学
Faculty	Basic Medical Sciences
Academic Background & Achievements	2008.9-2013.6 微生物与生化药学博士学位：中国药科大学完成国家自然科学基金青年基金项目以第一或通讯作者发表9篇SCI论文作为第一发明人申请2项发明专利
Work Experience	2013.9-2018.6 - 讲师 2018.7至今 - 副教授 2017.9至今 - 美国匹兹堡大学医学中心博士后研究员
Awards	2016年：“优秀中青年教师支持计划” 2016年：终考核“优秀”教职工 2017年：南医大留学生师资海外培训对象

University/Lab Affiliation and Title

南京医科大学

Faculty

Basic Medical Sciences

Academic Background & Achievements

2008.9-2013.6 微生物与生化药学博士学位：中国药科大学
完成国家自然科学基金青年基金项目
以第一或通讯作者发表9篇SCI论文
作为第一发明人申请2项发明专利

Work Experience

2013.9-2018.6 - 讲师
2018.7至今 - 副教授
2017.9至今 - 美国匹兹堡大学医学中心博士后研究员

Awards

2016年：“优秀中青年教师支持计划”
2016年：终考核“优秀”教职工
2017年：南医大留学生师资海外培训对象

Areas of Focus	肿瘤药理学
Publications	自噬在长期腹膜透析期间促进腹膜纤维化和凋亡。, Jingjing Wu, Changying Xing, Li Zhang, Huijuan Mao, Xuguan Chen, Mingxing Liang, Fang Wang, Haibin Ren, Hongqing Cui, Aiqin Jiang, Zibin Wang, Meijuan Zou(通讯作者), and Yong Ji., 2018 MicroRNA-3178通过靶向TRAF3改善由幽门螺杆菌新毒素Tip-α促进的炎症和胃癌发生。, Meijuan Zou, Fang Wang, Aiqin Jiang, Anliang Xia, Siya Kong, Chun Gong, Mingxia Zhu, Xin Zhou, Jun Zhu, Wei Zhu, Wenfang Cheng., 2017 AEG-1/MTDH激活的自噬增强人类恶性胶质瘤对TGF-β1触发的上皮-间质转化的易感性。, Meijuan Zou(通讯作者), Wei Zhu, Li Wang, Lei Shi, Rui Gao, Yingwei Ou, Xuguan Chen, Zhongchang Wang, Aiqin Jiang, Kunmei Liu, Ming Xiao, Ping Ni, Dandan Wu, Wenping He, Geng Sun, Ping Li, Sulan Zhai, Xuerong Wang, Gang Hu., 2016 通过靶向TGF-β R Ⅱ在TGF-β1诱导的纤维化过程中抑制hsa-miR-19a-3p/19b-3p的自噬。, Meijuan Zou, Fang Wang, Rui Gao, Jingjing Wu, Yingwei Ou, Xuguan Chen, Tongshan Wang, Xin Zhou, Wei Zhu, Ping Li, Lian-Wen Qi, Ting Jiang, Weiwei Wang, Chunyu Li, Jun Chen, Qifang He, Yan Chen., 2016 设计、合成和抗肿瘤活性的新型连接桥和B环修饰的Combretastatin A-4 (CA-4)类似物作为有效的抗微管蛋白剂。, Yong-Tao Duan, Ruo-Jun Man, Dan-Jie Tang, Yong-Fang Yao, Xiang-Xiang Tao, Chen Yu, Xin-Yi Liang, Meijuan Zou(通讯作者), Zhong-Chang Wang, Jigar A. Makawana, Hailiang Zhu., 2016 Oroxylin A通过mTOR-STAT3-Notch信号通路诱导人类恶性胶质瘤U251细胞的自噬。, Meijuan Zou, Chen Hu, Qidong You, Xuerong Wang, Qinglong Guo., 2015 Beclin 1介导的自噬在肝细胞癌细胞中的作用：通过抑制mTOR信号通路提高Oroxylin A的抗癌效率。, Meijuan Zou, Na Lu, Chen Hu, Wei Liu, Yajing Sun, Xiaotang Wang, Qidong You, Cong Gu, Tao Xi, Qinglong Guo., 2012 DYT-40，一种新型合成的2-苯乙烯基-5-硝基咪唑衍生物，通过抑制AEG-1和NF-κB信号通路阻止恶性胶质母细胞瘤的生长和侵袭。, Meijuan Zou (通讯作者), Yong-Tao Duan, Pengfei Wang, Rui Gao, Xuguan Chen, Yingwei Ou, Mingxing Liang, Zhongchang Wang, Yi Yuan, Li Wang, Hailiang Zhu., 2016 吴茱萸碱通过抑制β-连环蛋白介导的血管生成对肝细胞癌发挥抗肿瘤作用。, Le Shi, Fan Yang, Fei Luo, Yi Liu, Feng Zhang, Meijuan Zou, Qizhan Liu., 2016 E Platinum，一种新合成的铂化合物，通过抑制胃癌BGC-823细胞中mTOR的磷酸化诱导自噬。, Chen Hu, Meijuan Zou（共同第一作者）, Li Zhao, Na Lu, Yajing Sun, Shaohua Gou, Tao Xi, Qinglong Guo., 2012 Wogonoside通过调节MAPK-mTOR通路诱导MDA-MB-231细胞的自噬。, Yajing Sun, Meijuan Zou（共同第一作者）, Chen Hu, Yansu Qin, Xiuming Song, Na Lu, Qinglong Guo., 2013 Oroxylin A通过葡萄糖剥夺样机制使非小细胞肺癌细胞对失巢凋亡敏感：c-Src和己糖激酶II。, Libin Wei, Qinsheng Dai, Yuxin Zhou, Meijuan Zou, Zhiyu Li, Na Lu, Qinglong Guo., 2013 MicroRNA-125b通过靶向STARD13在MCF-7和MDA-MB-231乳腺癌细胞中诱导转移。, Feng Tang, Rui Zhang, Yunmian He, Meijuan Zou, Le Guo, Tao Xi., 2012 活性氧-线粒体通路参与FV-429诱导的人肝细胞癌HepG2细胞凋亡。, Zhen Yang, Lei Qiang, Tian Wu, Feihong Chen, Huiying Yang, Qing Zhao, Meijuan Zou, Yajing Sun, Zhiyu Li, Qinglong Guo., 2011 LFG-500，一种新合成的黄酮类化合物，在肝癌细胞中诱导活性氧-线粒体介导的凋亡。, Tian Wu, Lei Qiang, Feihong Chen, Qing Zhao, Zhen Yang, Meijuan Zou, Yajing Sun, Zhiyu Li, Qinglong Guo., 2011 藤黄酸诱导的突变p53降解由蛋白酶体介导并与CHIP相关。, Jia Wang, Qing Zhao, Qi Qi, Hongyan Gu, Jingjing Rong, Rong Mu, Meijuan Zou, Lei Tao, Qidong You, Qinglong Guo., 2011 DHF-18，一种新合成的黄酮类化合物，在体内和体外诱导肝癌细胞的线粒体介导的凋亡。, Lingbo Zhang, Lei Qiang, Feihong Chen, Tian Wu, Jingjing Rong, Qing Zhao, Meijuan Zou, Zhen Yang, Qidong You, Zhiyu Li, Yulin Wu, Qinglong Guo., 2011 活性氧-线粒体通路参与LYG-202诱导的人肝细胞癌HepG2细胞凋亡。, Feihong Chen, Lingbo Zhang, Lei Qiang, Zhen Yang, Tian Wu, Meijuan Zou, Lei Tao, Qidong You, Zhiyu Li, Yong Yang, Qinglong Guo., 2010 黄芩素通过下调NF-kappaB和调节其代谢增强低剂量5-氟尿嘧啶对胃癌的抗肿瘤作用。, Qing Zhao, Jia Wang, Meijuan Zou, Rong Hu, Li Zhao, Lei Qiang, Jingjing Rong, Qidong You, Qinglong Guo., 2010

Areas of Focus

肿瘤药理学

Publications

自噬在长期腹膜透析期间促进腹膜纤维化和凋亡。, Jingjing Wu, Changying Xing, Li Zhang, Huijuan Mao, Xuguan Chen, Mingxing Liang, Fang Wang, Haibin Ren, Hongqing Cui, Aiqin Jiang, Zibin Wang, Meijuan Zou*(通讯作者), and Yong Ji., 2018
MicroRNA-3178通过靶向TRAF3改善由幽门螺杆菌新毒素Tip-α促进的炎症和胃癌发生。, Meijuan Zou, Fang Wang, Aiqin Jiang, Anliang Xia, Siya Kong, Chun Gong, Mingxia Zhu, Xin Zhou, Jun Zhu, Wei Zhu*, Wenfang Cheng*., 2017
AEG-1/MTDH激活的自噬增强人类恶性胶质瘤对TGF-β1触发的上皮-间质转化的易感性。, Meijuan Zou*(通讯作者), Wei Zhu, Li Wang, Lei Shi, Rui Gao, Yingwei Ou, Xuguan Chen, Zhongchang Wang, Aiqin Jiang, Kunmei Liu, Ming Xiao, Ping Ni, Dandan Wu, Wenping He, Geng Sun, Ping Li, Sulan Zhai, Xuerong Wang, Gang Hu., 2016
通过靶向TGF-β R Ⅱ在TGF-β1诱导的纤维化过程中抑制hsa-miR-19a-3p/19b-3p的自噬。, Meijuan Zou, Fang Wang, Rui Gao, Jingjing Wu, Yingwei Ou, Xuguan Chen, Tongshan Wang, Xin Zhou, Wei Zhu*, Ping Li, Lian-Wen Qi, Ting Jiang, Weiwei Wang, Chunyu Li, Jun Chen, Qifang He, Yan Chen*., 2016
设计、合成和抗肿瘤活性的新型连接桥和B环修饰的Combretastatin A-4 (CA-4)类似物作为有效的抗微管蛋白剂。, Yong-Tao Duan, Ruo-Jun Man, Dan-Jie Tang, Yong-Fang Yao, Xiang-Xiang Tao, Chen Yu, Xin-Yi Liang, Meijuan Zou*(通讯作者), Zhong-Chang Wang, Jigar A. Makawana, Hailiang Zhu., 2016
Oroxylin A通过mTOR-STAT3-Notch信号通路诱导人类恶性胶质瘤U251细胞的自噬。, Meijuan Zou, Chen Hu, Qidong You, Xuerong Wang*, Qinglong Guo*., 2015
Beclin 1介导的自噬在肝细胞癌细胞中的作用：通过抑制mTOR信号通路提高Oroxylin A的抗癌效率。, Meijuan Zou, Na Lu, Chen Hu, Wei Liu, Yajing Sun, Xiaotang Wang, Qidong You, Cong Gu, Tao Xi*, Qinglong Guo*., 2012
DYT-40，一种新型合成的2-苯乙烯基-5-硝基咪唑衍生物，通过抑制AEG-1和NF-κB信号通路阻止恶性胶质母细胞瘤的生长和侵袭。, Meijuan Zou* (通讯作者), Yong-Tao Duan, Pengfei Wang, Rui Gao, Xuguan Chen, Yingwei Ou, Mingxing Liang, Zhongchang Wang, Yi Yuan, Li Wang, Hailiang Zhu., 2016
吴茱萸碱通过抑制β-连环蛋白介导的血管生成对肝细胞癌发挥抗肿瘤作用。, Le Shi, Fan Yang, Fei Luo, Yi Liu, Feng Zhang, Meijuan Zou, Qizhan Liu*., 2016
E Platinum，一种新合成的铂化合物，通过抑制胃癌BGC-823细胞中mTOR的磷酸化诱导自噬。, Chen Hu, Meijuan Zou（共同第一作者）, Li Zhao, Na Lu, Yajing Sun, Shaohua Gou, Tao Xi*, Qinglong Guo*., 2012
Wogonoside通过调节MAPK-mTOR通路诱导MDA-MB-231细胞的自噬。, Yajing Sun, Meijuan Zou（共同第一作者）, Chen Hu, Yansu Qin, Xiuming Song, Na Lu*, Qinglong Guo*., 2013
Oroxylin A通过葡萄糖剥夺样机制使非小细胞肺癌细胞对失巢凋亡敏感：c-Src和己糖激酶II。, Libin Wei, Qinsheng Dai, Yuxin Zhou, Meijuan Zou, Zhiyu Li, Na Lu*, Qinglong Guo*., 2013
MicroRNA-125b通过靶向STARD13在MCF-7和MDA-MB-231乳腺癌细胞中诱导转移。, Feng Tang, Rui Zhang, Yunmian He, Meijuan Zou, Le Guo, Tao Xi*., 2012
活性氧-线粒体通路参与FV-429诱导的人肝细胞癌HepG2细胞凋亡。, Zhen Yang, Lei Qiang, Tian Wu, Feihong Chen, Huiying Yang, Qing Zhao, Meijuan Zou, Yajing Sun, Zhiyu Li, Qinglong Guo*., 2011
LFG-500，一种新合成的黄酮类化合物，在肝癌细胞中诱导活性氧-线粒体介导的凋亡。, Tian Wu, Lei Qiang, Feihong Chen, Qing Zhao, Zhen Yang, Meijuan Zou, Yajing Sun, Zhiyu Li, Qinglong Guo*., 2011
藤黄酸诱导的突变p53降解由蛋白酶体介导并与CHIP相关。, Jia Wang, Qing Zhao, Qi Qi, Hongyan Gu, Jingjing Rong, Rong Mu, Meijuan Zou, Lei Tao, Qidong You, Qinglong Guo*., 2011
DHF-18，一种新合成的黄酮类化合物，在体内和体外诱导肝癌细胞的线粒体介导的凋亡。, Lingbo Zhang, Lei Qiang, Feihong Chen, Tian Wu, Jingjing Rong, Qing Zhao, Meijuan Zou, Zhen Yang, Qidong You, Zhiyu Li, Yulin Wu, Qinglong Guo*., 2011
活性氧-线粒体通路参与LYG-202诱导的人肝细胞癌HepG2细胞凋亡。, Feihong Chen, Lingbo Zhang, Lei Qiang, Zhen Yang, Tian Wu, Meijuan Zou, Lei Tao, Qidong You, Zhiyu Li, Yong Yang, Qinglong Guo*., 2010
黄芩素通过下调NF-kappaB和调节其代谢增强低剂量5-氟尿嘧啶对胃癌的抗肿瘤作用。, Qing Zhao, Jia Wang, Meijuan Zou, Rong Hu, Li Zhao, Lei Qiang, Jingjing Rong, Qidong You, Qinglong Guo*., 2010

肿瘤药理学癌症自噬胶质瘤 Tgf-Β1 Aeg-1 转移 Dna甲基化 Mir-3178

钱鹏旭 - 浙江大学

刘贇 - 复旦大学

魏湲颜 - 复旦大学

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