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巩加鑫
Basic Medical Sciences
南方医科大学
广东
Language: 中文, 英文
机械感觉
机械门控离子通道
机械转导
剪切力
Trpa1
神经环路
行为
分子机制
细胞机制
生理功能
Areas of Focus
- 机械感觉的分子细胞机制及其生理功能研究
Work Experience
- 2014.07-2014.10 - 上海睿智化学 - 高级科研员
- 2015.02-2016.01 - 伍斯特理工学院物理系 - 博士后
- 2016.02-2023.05 - 马萨诸塞州大学医学院 - 博士后
- 2023.08-至今 - 南方医科大学脑中心 - 教授
Academic Background & Achievements
- 2005.09-2009.07 学士: 中山大学
- 2009.09-2014.07 博士: 中国科学院神经科学研究所
Publications
- TrpA1 is a shear stress mechanosensing channel regulating intestinal stem cell proliferation in Drosophila, Jiaxin Gong, Niraj K. Nirala, Jiazhang Chen, Fei Wang, Pengyu Gu, Qi Wen, Y. Tony Ip, Yang Xiang, 2023
- Gliotransmission and adenosine signaling promote axon regeneration, Fei Wang, Kendra Takle Ruppell, Songlin Zhou, Yun Qu, Jiaxin Gong, Ye Shang, Jinglin Wu, Xin Liu, Wenlin Diao, Yi Li, Yang Xiang, 2023
- Shear stress activates nociceptors to drive Drosophila mechanical nociception, Jiaxin Gong, Jiazhang Chen, Pengyu Gu, Ye Shang, Kendra Takle Ruppell, Ying Yang, Fei Wang, Qi Wen, Yang Xiang, 2022
- Nociception and hypersensitivity involve distinct neurons and molecular transducers in Drosophila, Pengyu Gu, Fei Wang, Ye Shang, Jingjing Liu, Jiaxin Gong, Wei Xie, Junhai Han, Yang Xiang, 2022
- Polymodal Nociception in Drosophila Requires Alternative Splicing of TrpA1, Pengyu Gu, Jiaxin Gong, Ye Shang, Fei Wang, Kendra T. Ruppell, Zhiguo Ma, Amy E. Sheehan, Marc R. Freeman, Yang Xiang, 2019
- The Mechanosensitive Ion Channel Piezo Inhibits Axon Regeneration, Song Y, Li D, Farrelly O, Miles L, Li F, Kim SE, Lo TY, Wang F, Li T, Thompson-Peer KL, Gong J, Murthy SE, Coste B, Yakubovich N, Patapoutian A, Xiang Y, Rompolas P, Jan LY, Jan YN, 2019
- Aligned Nanotopography Promotes a Migratory State in Glioblastoma Multiforme Tumor Cells, Beliveau A, Thomas G, Gong J, Wen Q, Jain A, 2016
- Parallel pathways convey olfactory information with opposite polarities in Drosophila, Wang, K., Gong, J., Wang, Q., Li, H., Cheng, Q., Liu, Y., Zeng, S., Wang, Z., 2014
- NOMPC is likely a key component of Drosophila mechanotransduction channels, Gong, J., Wang, Q., Wang, Z., 2013
- Calpain activation promotes bace1 expression, APP processing, and amyloid plaque formation in a transgenic mouse model of Alzheimer disease, Liang, B., Duan, B.Y., Zhou, X.P., Gong, J.X., Luo, Z.G., 2010
