Professor | 刘主 | 数字化转型顾问

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Name	刘主
Contact Information	liuzhu@mail.hzau.edu.cn
Language ability	中文, 英语
Province	湖北

Upload Avatar (500 x 500)

Name

刘主

Contact Information

liuzhu@mail.hzau.edu.cn

Language ability

中文, 英语

Province

湖北

University/Lab Affiliation and Title	华中农业大学
Faculty	Life Sciences
Academic Background & Achievements	2009-2014: 中国科学院大学武汉物理与数学研究所无线电物理博士
Work Experience	2018-至今: 华中农业大学生命科学技术学院教授 2014-2017: 浙江大学基础医学院博士后

University/Lab Affiliation and Title

华中农业大学

Faculty

Life Sciences

Academic Background & Achievements

2009-2014: 中国科学院大学武汉物理与数学研究所无线电物理博士

Work Experience

2018-至今: 华中农业大学生命科学技术学院教授
2014-2017: 浙江大学基础医学院博士后

Areas of Focus	蛋白质功能的结构基础蛋白质动态学研究方法的开发与应用蛋白质功能激活与调控的动态学和动力学过程
Publications	The cytoplasmic synthesis and coupled membrane translocation of eukaryotic polyphosphate by signal-activated VTC complex, Guan, Z., Chen, J., Liu, R., Chen, Y., Xing, Q., Du, Z., Cheng, M., Hu, J., Zhang, W., Mei, W., Wan, B., Wang, Q., Zhang, J., Cheng, P., Cai, H., Cao, J., Zhang, D., Yan, J., Yin, P., Hothorn, M. & Liu, Z., 2023 Insights into the mechanism of phospholipid hydrolysis by plant non-specific phospholipase C, Fan, R., Zhao, F., Gong, Z., Chen, Y., Yang, B., Zhou, C., Zhang, J., Du, Z., Wang, X., Yin, P., Guo, L. & Liu, Z., 2023 Parkin-mediated ubiquitination inhibits BAK apoptotic activity by blocking its canonical hydrophobic groove, Cheng, P., Hou, Y. Z., Bian, M. X., Fang, X. R., Liu, Y., Rao, Y. F., Cao, S., Liu, Y. J., Zhang, S., Chen, Y. K., Dong, X. & Liu, Z., 2023 Mechanistic insights into the regulation of plant phosphate homeostasis by the rice SPX2 - PHR2 complex, Guan, ZY, Zhang, QX, Zhang, ZF, Zuo, JQ, Chen, J, Liu, R, Savarin, J., Broger, L., Cheng, P, Wang, Q, Pei, K, Zhang, DL, Zou, TT, Yan, JJ, Yin, P, Hothorn, M. & Liu, Z., 2022 AimR Adopts Preexisting Dimer Conformations for Specific Target Recognition in Lysis-Lysogeny Decisions of Bacillus Phage phi3T, Pei, K, Zhang, J, Zou, TT & Liu, Z., 2021 BMPQ-1 binds selectively to (3+1) hybrid topologies in human telomeric G-quadruplex multimers, Gao C, Liu Z, Hou HT, Ding JQ, Chen X, Xie CB, Song ZB, Hu Z, Feng MQ, Mohamed Hany I., Xu SZ, Parkinson Gary N., Haider Shozeb, Wei DG., 2020 Structural basis of tubulin detyrosination by VASH2/SVBP heterodimer, Zhou C, Yan L, Zhang WH, Liu Z., 2019 Structural basis for the recognition of K48-linked Ub chain by proteasomal receptor Rpn13, Liu Z, Dong X, Yi HW, Yang J, Gong Z, Wang Y, Liu K, Zhang WP, Tang C., 2019 Characterizing Protein Dynamics with Integrative Use of Bulk and Single-Molecule Techniques, Liu Z, Gong Z, Cao Y, Ding YH, Dong MQ, Lu YB, Zhang WP, Tang C., 2018 Ubiquitin S65 phosphorylation engenders a pH-sensitive conformational switch, Dong X, Gong Z, Lu YB, Liu K, Qing LY, Ran ML, Zhang CL, Liu Z, Zhang WP, Tang C., 2017 Transient protein-protein interactions visualized by solution NMR, Liu Z, Gong Z, Dong X and Tang C., 2016 Lys63-linked ubiquitin chain adopts multiple conformational states for specific target recognition, Liu Z, Gong Z, Jiang WX, Yang J, Zhu WK, Guo DC, Zhang WP, Liu ML and Tang C., 2015 Subtle dynamics of holo glutamine binding protein revealed with a rigid paramagnetic probe, Liu Z, Gong Z, Guo DC, Zhang WP and Tang C., 2014 Noncovalent dimerization of ubiquitin, Liu Z, Zhang WP, Xing Q, Ren XF, Liu ML and Tang C., 2012

Areas of Focus

蛋白质功能的结构基础
蛋白质动态学研究方法的开发与应用
蛋白质功能激活与调控的动态学和动力学过程

Publications

The cytoplasmic synthesis and coupled membrane translocation of eukaryotic polyphosphate by signal-activated VTC complex, Guan, Z., Chen, J., Liu, R., Chen, Y., Xing, Q., Du, Z., Cheng, M., Hu, J., Zhang, W., Mei, W., Wan, B., Wang, Q., Zhang, J., Cheng, P., Cai, H., Cao, J., Zhang, D., Yan, J., Yin, P., Hothorn, M. & Liu, Z., 2023
Insights into the mechanism of phospholipid hydrolysis by plant non-specific phospholipase C, Fan, R., Zhao, F., Gong, Z., Chen, Y., Yang, B., Zhou, C., Zhang, J., Du, Z., Wang, X., Yin, P., Guo, L. & Liu, Z., 2023
Parkin-mediated ubiquitination inhibits BAK apoptotic activity by blocking its canonical hydrophobic groove, Cheng, P., Hou, Y. Z., Bian, M. X., Fang, X. R., Liu, Y., Rao, Y. F., Cao, S., Liu, Y. J., Zhang, S., Chen, Y. K., Dong, X. & Liu, Z., 2023
Mechanistic insights into the regulation of plant phosphate homeostasis by the rice SPX2 - PHR2 complex, Guan, ZY, Zhang, QX, Zhang, ZF, Zuo, JQ, Chen, J, Liu, R, Savarin, J., Broger, L., Cheng, P, Wang, Q, Pei, K, Zhang, DL, Zou, TT, Yan, JJ, Yin, P, Hothorn, M. & Liu, Z., 2022
AimR Adopts Preexisting Dimer Conformations for Specific Target Recognition in Lysis-Lysogeny Decisions of Bacillus Phage phi3T, Pei, K, Zhang, J, Zou, TT & Liu, Z., 2021
BMPQ-1 binds selectively to (3+1) hybrid topologies in human telomeric G-quadruplex multimers, Gao C, Liu Z, Hou HT, Ding JQ, Chen X, Xie CB, Song ZB, Hu Z, Feng MQ, Mohamed Hany I., Xu SZ, Parkinson Gary N., Haider Shozeb, Wei DG., 2020
Structural basis of tubulin detyrosination by VASH2/SVBP heterodimer, Zhou C, Yan L, Zhang WH, Liu Z., 2019
Structural basis for the recognition of K48-linked Ub chain by proteasomal receptor Rpn13, Liu Z, Dong X, Yi HW, Yang J, Gong Z, Wang Y, Liu K, Zhang WP, Tang C., 2019
Characterizing Protein Dynamics with Integrative Use of Bulk and Single-Molecule Techniques, Liu Z, Gong Z, Cao Y, Ding YH, Dong MQ, Lu YB, Zhang WP, Tang C., 2018
Ubiquitin S65 phosphorylation engenders a pH-sensitive conformational switch, Dong X, Gong Z, Lu YB, Liu K, Qing LY, Ran ML, Zhang CL, Liu Z, Zhang WP, Tang C., 2017
Transient protein-protein interactions visualized by solution NMR, Liu Z, Gong Z, Dong X and Tang C., 2016
Lys63-linked ubiquitin chain adopts multiple conformational states for specific target recognition, Liu Z, Gong Z, Jiang WX, Yang J, Zhu WK, Guo DC, Zhang WP, Liu ML and Tang C., 2015
Subtle dynamics of holo glutamine binding protein revealed with a rigid paramagnetic probe, Liu Z, Gong Z, Guo DC, Zhang WP and Tang C., 2014
Noncovalent dimerization of ubiquitin, Liu Z, Zhang WP, Xing Q, Ren XF, Liu ML and Tang C., 2012

蛋白质结构晶体学冷冻电镜核磁共振单分子荧光 Flim-Fret 小角X光散射化学交联质谱分子动力学生物物理

牛锋锋 - 南方科技大学

隋森芳 - 南方科技大学

沈庆涛 - 南方科技大学

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