张晓妍
xiaoyanz@mail.hzau.edu.cn
中文, 英语
湖北
华中农业大学
College of Biomedical and Health
  • 2001.9-2005.7 生物技术专业学士: 河北大学
  • 2005.9-2010.7 细胞生物学专业博士: 北京大学
  • 2010.8-2015.7 - 密歇根大学 - 研究员
  • 2015.8-2019.7 - 密歇根大学 - 中级研究实验室专家
  • 2019.8-至今 - 华中农业大学 - 教授
高尔基体的结构与功能
细胞自噬
  • Nonredundant roles of GRASP55 and GRASP65 in the Golgi apparatus and Beyond, Zhang X*, Wang Y*, 2020
  • GORASP2/GRASP55 collaborates with the PtdIns3K UVRAG complex to facilitate autophagosome-lysosome fusion, Zhang X#, Wang L#, Ireland SC, Ahat E, Li J, Bekier II ME, Zhang Z, Wang Y*, 2019
  • GRASP55 senses glucose deprivation through O-GlcNAcylation to promote autophagosome-lysosome fusion, Zhang X*, Wang L, Lak B, Li J, Jokitalo E, Wang Y*, 2018
  • The Golgi stacking protein GORASP2/GRASP55 serves as an energy sensor to promote autophagosome maturation under glucose starvation, Zhang X*, Wang Y*, 2018
  • GRASP55 facilitates autophagosome maturation under glucose deprivation, Zhang X*, Wang Y*, 2018
  • Regulation of protein glycosylation and sorting by the Golgi matrix proteins GRASP55/65, Xiang Y#, Zhang X#, Nix DB, Katoh T, Aoki K, Tiemeyer M, Wang Y*, 2013
  • Glycosylation Quality Control by the Golgi Structure, Zhang X, Wang Y*, 2016
  • GRASPs in Golgi Structure and Function, Zhang X, Wang Y*, 2016
  • SIRT2 deacetylates GRASP55 to facilitate post-mitotic Golgi assembly, Zhang X, Brachner A, Kukolj E, Slade D*, Wang Y*, 2019
  • Cell cycle regulation of VCIP135 deubiquitinase activity and function in p97/p47-mediated Golgi reassembly, Zhang X, Wang Y*, 2015
  • Phosphorylation regulates VCIP135 function in Golgi membrane fusion during the cell cycle, Zhang X, Zhang H, Wang Y*, 2014
  • Sequential phosphorylation of Nedd1 by Cdk1 and Plk1 is required for targeting of the γTuRC to the centrosome, Zhang X, Chen Q, Feng J, Hou J, Yang F, Liu J, Jiang Q, Zhang C*, 2009
  • DNA damage promotes microtubule dynamics through a DNA-PK-AKT axis for enhanced repair, Ma S, Rong Z, Liu C, Qin X, Zhang X, Chen Q*, 2021
  • Cytosolic Ca2+ Modulates Golgi Structure Through PKCα-Mediated GRASP55 Phosphorylation, Ireland S, Ramnarayanan S, Fu M, Zhang X, Zhang J, Li J, Emebo D, Wang Y*, 2020
  • GRASP depletion-mediated Golgi destruction decreases cell adhesion and migration via the reduction of α5β1 integrin, Ahat E, Xiang Y, Zhang X, Bekier ME II, Wang Y*, 2019
  • Knockout of the Golgi stacking proteins GRASP55 and GRASP65 impairs Golgi structure and function, Bekier, M, Wang L, Li J, Huang H, Tang D, Zhang X, Wang Y*, 2017
  • Mena-GRASP65 interaction couples actin polymerization to Golgi ribbon linking, Tang D, Zhang X, Huang S, Yuan H, Li J, Wang Y*, 2016
  • Usp16 regulates kinetochore localization of Plk1 to promote proper chromosome alignment in mitosis, Zhuo X, Guo X, Zhang X, Jing G, Wang Y, Chen Q, Jiang Q, Liu J, Zhang C*, 2015
  • Altered cofactor regulation with disease-associated p97/VCP mutations, Zhang X, Gui L, Zhang X, Bulfer SL, Sanghez V, Wong DE, Lee Y, Lehmann L, Lee JS, Shih PY, Lin HJ, Iacovino M, Weihl CC, Arkin MR, Wang Y, Chou TF*, 2015
  • PCM1 recruits Plk1 to the pericentriolar matrix to promote primary cilia disassembly before mitotic entry, Wang G, Chen Q, Zhang X, Zhang B, Zhuo X, Liu J, Jiang Q, Zhang C*, 2013
  • Cyclin B1 is localized to unattached kinetochores and contributes to efficient microtubule attachment and proper chromosome alignment during mitosis, Chen Q, Zhang X, Jiang Q, Clarke PR, Zhang C*, 2008
高尔基体 结构 功能 细胞生物学 蛋白质 自噬 细胞过程 生物化学 分子生物学 研究

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