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王文涛
Life Science
中山大学
广东
Language: 中文, 英文
Rna
生物学
功能
非编码
疾病
白血病
Ncrna
研究
生物化学
分子
Areas of Focus
- RNA功能生物学
- 非编码RNA与疾病
Work Experience
- 2021-至今: 中山大学生命科学学院副教授
- 2017-2021: 中山大学生命科学学院特聘副研究员
Academic Background & Achievements
- 2014-2017: 中山大学生物化学与分子生物学博士
- 2011-2014: 中山大学生物化学与分子生物学硕士
- 2006-2010: 湖北大学双学位
- 成就: 在非编码RNA的疾病发生发展研究中取得重要进展，获得同行认可
Publications
- METTL3 protects METTL14 from STUB1-mediated degradation to maintain m6A homeostasis., Zeng ZC, Pan Q, Sun YM, Huang HJ, Chen XT, Chen TQ, He B, Ye H, Zhu SX, Pu KJ, Fang K, Huang W, Chen YQ, Wang WT*., 2023
- The snoRNA-like lncRNA LNC-SNO49AB drives leukemia by activating the RNA-editing enzyme ADAR1., Huang W, Sun YM, Pan Q, Fang K, Chen XT, Zeng ZC, Chen TQ, Zhu SX, Huang LB, Luo XQ, Wang WT*, Chen YQ*., 2022
- Chromatin-associated orphan snoRNA regulates DNA damage-mediated differentiation via a non-canonical complex., Han, C, Sun LY, Luo XQ, Pan Q, Sun YM, Zeng ZC, Chen TQ, Huang W, Fang K, Wang WT*, Chen YQ*., 2022
- The oncomicropeptide APPLE promotes hematopoietic malignancy by enhancing translation initiation., Sun LY #, Wang WT #, Han C #, Huang W, Sun YM, Fang K, Zeng ZC, Yang QQ, Pan Q, Chen TQ, Luo XQ, Chen YQ*., 2021
- The m6A writers regulated by the IL-6/STAT3 inflammatory pathway facilitate cancer cell stemness in cholangiocarcinoma., Ye H#, Chen TQ#, Zeng ZC#, He B, Yang QQ, Pan Q, Chen YQ, Wang WT*., 2022
- Small nucleolar RNA is potential as a novel player in leukemogenesis and clinical application., Lin LM, Pan Q, Sun YM, Wang WT*., 2021
- Cis-acting lnc-eRNA SEELA directly binds histone H4 to promote histone recognition and leukemia progression., Fang K#, Huang W#, Sun YM, Chen TQ, Zeng ZC, Yang QQ, Pan Q, Han C, Sun LY, Luo XQ, Wang WT*, Chen YQ*., 2020
- The lncRNA LAMP5-AS1 drives leukemia cell stemness by directly modulating DOT1L methyltransferase activity in MLL leukemia., Wang WT, Chen TQ, Zeng ZC, Pan Q, Huang W, Han C, Fang K, Sun LY, Yang QQ, Wang D, Luo XQ, Sun YM*, Chen YQ*., 2020
- Nuclear export of chimeric mRNAs depends on an lncRNA-triggered autoregulatory loop in blood malignancies., Chen ZH#, Chen TQ#, Zeng ZC, Wang D, Han C, Sun YM, Huang W, Sun LY, Fang K, Chen YQ, Luo XQ, Wang WT*., 2020
- CircMYBL2, a circRNA from MYBL2, Regulates FLT3 Translation by Recruiting PTBP1 to Promote FLT3-ITD AML Progression., Sun YM#, Wang WT#, Zeng ZC, Chen TQ, Han C, Pan Q, Huang W, Fang K, Sun LY, Zhou YF, Luo XQ, Luo C, Du X, Chen YQ*., 2019
- Activation of the lysosome-associated membrane protein LAMP5 by DOT1L serves as a bodyguard for MLL fusion oncoproteins to evade degradation in leukemia., Wang WT#, Han C#, Sun YM#, Chen ZH, Fang K, Huang W, Sun LY, Zeng ZC, Luo XQ, Chen YQ*., 2019
- Noncoding RNAs in cancer therapy resistance and targeted drug development., Wang WT#, Han C#, Sun YM, Chen TQ, Chen YQ*., 2019
- circRNA circAF4 functions as an oncogene to regulate MLL-AF4 fusion protein expression and inhibit MLL leukemia progression., Huang W#, Fang K#, Chen TQ, Zeng ZC, Sun YM, Han C, Sun LY, Chen ZH, Yang QQ, Pan Q, Luo XQ, Wang WT*, Chen YQ*., 2019
- LncRNA ANRIL regulates AML development through modulating the glucose metabolism pathway of AdipoR1/AMPK/SIRT1., Sun LY#, Li XJ#, Sun YM, Huang W, Fang K, Han C, Chen ZH, Luo XQ, Chen YQ*, Wang WT*., 2018
- Global identification and characterization of lncRNAs that control inflammation in malignant cholangiocytes., Han BW#, Ye H#, Wei PP, He B, Han C, Chen ZH, Chen YQ*, Wang WT*., 2018
