Professor | 张力圩 | 数字化转型顾问

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Name	张力圩
Contact Information	lwzhanghz@cau.edu.cn
Language ability	中文, 英文
Province	北京

Upload Avatar (500 x 500)

Name

张力圩

Contact Information

lwzhanghz@cau.edu.cn

Language ability

中文, 英文

Province

北京

University/Lab Affiliation and Title	中国农业大学
Faculty	department of nutrition and health
Academic Background & Achievements	2011.09-2016.06 理学博士: 中国农业大学 2007.09-2011.06 工学学士: 大连理工大学
Work Experience	2023.05-至今 - 中国农业大学 - 副教授 2023.01-2023.05 - 广州市妇女儿童医疗中心 - 副研究员 2019.07-2022.12 - 中国科学院生物物理研究所 - 助理研究员 2016.08-2019.06 - 中国科学院生物物理研究所 - 博士后

University/Lab Affiliation and Title

中国农业大学

Faculty

department of nutrition and health

Academic Background & Achievements

2011.09-2016.06 理学博士: 中国农业大学
2007.09-2011.06 工学学士: 大连理工大学

Work Experience

2023.05-至今 - 中国农业大学 - 副教授
2023.01-2023.05 - 广州市妇女儿童医疗中心 - 副研究员
2019.07-2022.12 - 中国科学院生物物理研究所 - 助理研究员
2016.08-2019.06 - 中国科学院生物物理研究所 - 博士后

Areas of Focus	基于生物信息学，开发高通量数据挖掘的算法，探索衰老和发育相关疾病的表观遗传学和免疫学机制通过宏基因组学方法，针对益生菌、膳食纤维等功能食品，研究其调节肠道菌群和改善宿主病理状态的功能机制基于网络爬虫和数据库技术，开发营养与健康大数据平台
Publications	Recognition of cyclic dinucleotides and folates by human SLC19A1, Qixiang Zhang, Xuyuan Zhang, Yalan Zhu, Panpan Sun, Liwei Zhang, Junxiao Ma, Yong Zhang, Lingan Zeng, Xiaohua Nie, Yina Gao, Zhaolong Li, Songqing Liu, Jizhong Lou, Ang Gao, Liguo Zhang, Pu Gao, 2022 Human IFNAR2 Mutant Generated by CRISPR/Cas9-Induced Exon Skipping Upregulates a Subset of Tonic-Like Interferon-Stimulated Genes Upon IFNβ Stimulation, Linnan Zhang, Jianping Ma, Xiaoyang Jin, Liwei Zhang, Mengfan Zhang, Patrick Z Li, Jingyun Li, Liguo Zhang, 2022 HIRA complex presets transcriptional potential through coordinating depositions of the histone variants H3.3 and H2A.Z on the poised genes in mESCs, Yang Yang, Liwei Zhang, Chaoyang Xiong, Jun Chen, Li Wang, Zengqi Wen, Juan Yu, Ping Chen, Yanhui Xu, Jingji Jin, Yong Cai, Guohong Li, 2022 H2A.Z Facilitates Licensing and Activation of Early Replication Origins, Haizhen Long, Liwei Zhang, Mengjie Lv, Zengqi Wen, Wenhao Zhang, Xiulan Chen, Peitao Zhang, Luyuan Chang, Caiwei Jin, Xi Wang, Fuquan Yang, Ping Chen, Raphael Margueron, Haiteng Deng, Mingzhao Zhu, Guohong Li, 2020 Histone variant H2A.Z regulates nucleosome unwrapping and CTCF binding in mouse ES cells, Zengqi Wen, Liwei Zhang, Haihe Ruan, Guohong Li, 2020 Transcription-coupled structural dynamics of topologically associating domains regulate replication origin efficiency, Yongzheng Li, Boxin Xue, Mengling Zhang, Liwei Zhang, Yingping Hou, Yizhi Qin, Haizhen Long, Qian Peter Su, Yao Wang, Xiaodong Guan, Yanyan Jin, Yuan Cao, Guohong Li, Yujie Sun, 2021 HBO1 is a versatile histone acyltransferase critical for promoter histone acylations, Yanhui Xiao, Wenjing Li, Hui Yang, Lulu Pan, Liwei Zhang, Lu Lu, Jiwei Chen, Wei Wei, Jie Ye, Jiwen Li, Guohong Li, Yong Zhang, Minjia Tan, Jianping Ding, Jiemin Wong, 2021 PlantEAR: functional analysis platform for plant EAR motif-containing proteins, Jiaotong Yang, Yue Liu, Hengyu Yan, Tian Tian, Qi You, Liwei Zhang, Wenying Xu, Zhen Su, 2018 ccNET: Database of co-expression networks with functional modules for diploid and polyploid Gossypium, Qi You, Wenying Xu, Kang Zhang, Liwei Zhang, Xin Yi, Dongxia Yao, Chunchao Wang, Xueyan Zhang, Xinhua Zhao, Nicholas Provart, Fuguang Li, Zhen Su, 2016 Down-regulation of OsSPX1 caused semi-male sterility, resulting in reduction of grain yield in rice, Kang Zhang, Qian Song, Qiang Wei, Chunchao Wang, Liwei Zhang, Wenying Xu, Zhen Su, 2016 GraP: Platform for Functional Genomics Analysis of Gossypium raimondii, Liwei Zhang, Jinyan Guo, Qi You, Xin Yi, Yi Ling, Wenying Xu, Jinping Hua, Zhen Su, 2015 SIFGD: Setaria italica Functional Genomics Database, Qi You, Liwei Zhang, Xin Yi, Zhenghai Zhang, Wengying Xu, and Zhen Su, 2015 Transcriptome analysis reveals that distinct metabolic pathways operate in salt-tolerant and salt-sensitive upland cotton varieties subjected to salinity stress, Jinyan Guo, Gongyao Shi, Liwei Zhang, Wenying Xu, Yumei Wang, Zhen Su, Jinping Hua, 2015 De novo transcriptome analysis of Medicago falcata reveals novel insights about the mechanisms underlying abiotic stress-responsive pathway, Zhenyan Miao, Wei Xu, Daofeng Li, Xiaona Hu, Jiaxing Liu, Rongxue Zhang, Zongyong Tong, Jiangli Dong, Zhen Su, Liwei Zhang, Min Sun, Wenjie Li, Zhenglin Du, Songnian Hu, Tao Wang, 2015

Areas of Focus

基于生物信息学，开发高通量数据挖掘的算法，探索衰老和发育相关疾病的表观遗传学和免疫学机制
通过宏基因组学方法，针对益生菌、膳食纤维等功能食品，研究其调节肠道菌群和改善宿主病理状态的功能机制
基于网络爬虫和数据库技术，开发营养与健康大数据平台

Publications

Recognition of cyclic dinucleotides and folates by human SLC19A1, Qixiang Zhang, Xuyuan Zhang, Yalan Zhu, Panpan Sun, Liwei Zhang, Junxiao Ma, Yong Zhang, Lingan Zeng, Xiaohua Nie, Yina Gao, Zhaolong Li, Songqing Liu, Jizhong Lou, Ang Gao, Liguo Zhang, Pu Gao, 2022
Human IFNAR2 Mutant Generated by CRISPR/Cas9-Induced Exon Skipping Upregulates a Subset of Tonic-Like Interferon-Stimulated Genes Upon IFNβ Stimulation, Linnan Zhang, Jianping Ma, Xiaoyang Jin, Liwei Zhang, Mengfan Zhang, Patrick Z Li, Jingyun Li, Liguo Zhang, 2022
HIRA complex presets transcriptional potential through coordinating depositions of the histone variants H3.3 and H2A.Z on the poised genes in mESCs, Yang Yang, Liwei Zhang, Chaoyang Xiong, Jun Chen, Li Wang, Zengqi Wen, Juan Yu, Ping Chen, Yanhui Xu, Jingji Jin, Yong Cai, Guohong Li, 2022
H2A.Z Facilitates Licensing and Activation of Early Replication Origins, Haizhen Long, Liwei Zhang, Mengjie Lv, Zengqi Wen, Wenhao Zhang, Xiulan Chen, Peitao Zhang, Luyuan Chang, Caiwei Jin, Xi Wang, Fuquan Yang, Ping Chen, Raphael Margueron, Haiteng Deng, Mingzhao Zhu, Guohong Li, 2020
Histone variant H2A.Z regulates nucleosome unwrapping and CTCF binding in mouse ES cells, Zengqi Wen, Liwei Zhang, Haihe Ruan, Guohong Li, 2020
Transcription-coupled structural dynamics of topologically associating domains regulate replication origin efficiency, Yongzheng Li, Boxin Xue, Mengling Zhang, Liwei Zhang, Yingping Hou, Yizhi Qin, Haizhen Long, Qian Peter Su, Yao Wang, Xiaodong Guan, Yanyan Jin, Yuan Cao, Guohong Li, Yujie Sun, 2021
HBO1 is a versatile histone acyltransferase critical for promoter histone acylations, Yanhui Xiao, Wenjing Li, Hui Yang, Lulu Pan, Liwei Zhang, Lu Lu, Jiwei Chen, Wei Wei, Jie Ye, Jiwen Li, Guohong Li, Yong Zhang, Minjia Tan, Jianping Ding, Jiemin Wong, 2021
PlantEAR: functional analysis platform for plant EAR motif-containing proteins, Jiaotong Yang, Yue Liu, Hengyu Yan, Tian Tian, Qi You, Liwei Zhang, Wenying Xu, Zhen Su, 2018
ccNET: Database of co-expression networks with functional modules for diploid and polyploid Gossypium, Qi You, Wenying Xu, Kang Zhang, Liwei Zhang, Xin Yi, Dongxia Yao, Chunchao Wang, Xueyan Zhang, Xinhua Zhao, Nicholas Provart, Fuguang Li, Zhen Su, 2016
Down-regulation of OsSPX1 caused semi-male sterility, resulting in reduction of grain yield in rice, Kang Zhang, Qian Song, Qiang Wei, Chunchao Wang, Liwei Zhang, Wenying Xu, Zhen Su, 2016
GraP: Platform for Functional Genomics Analysis of Gossypium raimondii, Liwei Zhang, Jinyan Guo, Qi You, Xin Yi, Yi Ling, Wenying Xu, Jinping Hua, Zhen Su, 2015
SIFGD: Setaria italica Functional Genomics Database, Qi You, Liwei Zhang, Xin Yi, Zhenghai Zhang, Wengying Xu, and Zhen Su, 2015
Transcriptome analysis reveals that distinct metabolic pathways operate in salt-tolerant and salt-sensitive upland cotton varieties subjected to salinity stress, Jinyan Guo, Gongyao Shi, Liwei Zhang, Wenying Xu, Yumei Wang, Zhen Su, Jinping Hua, 2015
De novo transcriptome analysis of Medicago falcata reveals novel insights about the mechanisms underlying abiotic stress-responsive pathway, Zhenyan Miao, Wei Xu, Daofeng Li, Xiaona Hu, Jiaxing Liu, Rongxue Zhang, Zongyong Tong, Jiangli Dong, Zhen Su, Liwei Zhang, Min Sun, Wenjie Li, Zhenglin Du, Songnian Hu, Tao Wang, 2015

生物信息学高通量数据挖掘表观遗传学免疫学衰老发育疾病益生菌膳食纤维肠道菌群

王然 - 中国农业大学

詹菁 - 中国农业大学

赵亮 - 中国农业大学

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