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齐湘兵
national institute of biological sciences，Beijing
北京生命科学研究所
北京
Language: 英语, 中文
有机合成
方法学
天然产物
全合成
小分子
靶点相互作用
药物发现
开发
高通量筛选
计算机辅助设计
Areas of Focus
- 有机合成方法学开发
- 天然产物全合成
- 小分子与靶点相互作用
- 药物发现与开发
Work Experience
- 2021年至今 - 北京生命科学研究所 - 高级研究员
- 2013年至今 - 北京生命科学研究所 - 化学中心主任
- 2010-2013年 - 美国德州大学西南医学中心 - 博士后
- 2009-2010年 - 美国伊利诺伊大学厄巴纳-香槟分校 - 博士后
- 2004-2005年 - 中科院上海有机所 - 研究助理
Academic Background & Achievements
- 2005-2009年 有机化学博士：美国德州大学西南医学中心
- 2001-2004年 有机化学硕士：同济大学
- 1997-2001年 应用化学学士：济南大学
Publications
- Unlocking the secrets to human NTCP structure, Xiangbing Qi, Wenhui Li, 2023
- Asymmetric synthesis alkylboranes via enantioselective cross-coupling of gem-Borazirconocene Alkanes, Chao Yang, Songlin Bai, Xiangbing Qi, 2023
- Total Syntheses of Tetrodotoxin, Peihao Chen, Jing Wang, Xiangbing Qi, 2023
- Asymmetric Total Syntheses of Strychnos Alkaloids via Selective Fischer Indolization, Xiaolei Liu, Mingliang Lou, Xiangbing Qi, 2022
- BAFinder: A software for unknown bile acid identification using accurate mass LC-MS/MS in positive and negative modes, Yan Ma, Yang Cao, Xiaocui Song, Yuanying Zhang, Jing Li, Yankai Wang, Xiaoqing Wu, Xiangbing Qi, 2022
- Flavin-Dependent Monooxygenase-Mediated 1,2-Oxazine Construction via Meisenheimer Rearrangement in the Biosynthesis of Paeciloxazine, Daojiang Yan, Kunya Wang, Songlin Bai, Bingyu Liu, Jian Bai, Xiangbing Qi, Youcai Hu, 2022
- Expeditious and Efficient ortho-Selective Trifluoromethane-sulfonylation of Arylhydroxylamines, Yue Liu, Songlin Bai, Yuanbo Du, Xiangbing Qi, Hongyin Gao, 2022
- A brief overview of classical natural product drug synthesis and bioactivity, Gen Li, Mingliang Lou, Xiangbing Qi, 2022
- Structure of PDE3A–SLFN12 complex and structure-based design for a potent apoptosis inducer of tumor cells, Jie Chen, Nan Liu, Yinpin Huang, Yuanxun Wang, Yuxing Sun, Hong-Wei Wang, Niu Huang, Xiangbing Qi, Xiaodong Wang, 2021
- Alkylzirconocenes in Organic Synthesis: An Overview, Chao Yang, Chao Jiang, Xiangbing Qi, 2021
- Shigella evades pyroptosis by arginine ADP-riboxanation of caspase-11, Zilin Li, Wang Liu, Jiaqi Fu, Sen Cheng, Yue Xu, Zhiqiang Wang, Xiaofan Liu, Xuyan Shi, Yaxin Liu, Xiangbing Qi, Xiaoyun Liu, Jingjin Ding, Feng Shao, 2021
- Design of Dimeric Bile Acid Derivatives as Potent and Selective Human NTCP Inhibitors, Yang Liu, Lei Zhang, Huan Yan, Zhiqiang Wang, Guoliang Sun, Xiao Song, Zhongmin Zhou, Bo Peng, Liwei Yan, Qingcui Wu, Wenhui Li, Xiangbing Qi, 2021
- Total Synthesis of (-)-Alstofolinine A through a Furan Oxidation/Rearrangement and Indole Nucleophilic Cyclization Cascade, Lei Zhang, Ye Zhang, Wenting Li, Xiangbin Qi, 2019
- Exploring Halogen Bonds in 5-Hydroxytryptamine 2B Receptor–Ligand Interactions, Yu Zhou, Yuanxun Wang, Pengfei Li, Xi-Ping Huang, Xiangbing Qi, Yunfei Du, Niu Huang, 2018
- Response dynamics of midbrain dopamine neurons and serotonin Interactions neurons to heroin, nicotine, cocaine, and MDMA, Chao Wei, Xiao Han, Danwei Weng, Qiru Feng, Xiangbing Qi, Jin Li, Minmin Luo, 2018
- Development of the Vinylogous Pictet-Spengler Cyclization and Total Synthesis of (±)‐Lundurine A, Aaron Nash, Xiangbing Qi, Pradip Maity, Kyle Owens, Uttam K. Tambar, 2018
- A hybridization-chain-reaction-based method for amplifying immunosignals, Rui Lin, Qiru Feng, Peng Li, Ping Zhou, Ruiyu Wang, Zhe Liu, Zhiqiang Wang, Xiangbing Qi, Nan Tang, Feng Shao, Minmin Luo, 2018
- A general strategy for synthesis of cyclophane-braced peptide macrocycles via palladium-catalysed intramolecular sp 3 C− H arylation, Xuekai Zhang, Gang Lu, Meng Sun, Madhu Mahankali, Yanfei Ma, Mingming Zhang, Wangde Hua, Yuting Hu, Qingbing Wang, Jinghuo Chen, Gang He, Xiangbing Qi, Weijun Shen, Peng Liu, Gong Chen, 2018
- Staurosporine targets the Hippo pathway to inhibit cell growth, Xueyan Ma, Peixue Li, Peihao Chen, Jinhui Li, Hongling Huang, Chao Wang, Wenjing Li, Jianping Ding, Yun Zhao, Fa-Xing Yu, Xiangbing Qi, Lei Zhang, 2018
- In Silico Identification of a Novel Hinge-Binding Scaffold for Kinase Inhibitor Discovery, Yanli Wang, Yuze Sun, Ran Cao, Dan Liu, Yuting Xie, Li Li, Xiangbing Qi, Niu Huang, 2017
- Development of Dihydroxyphenyl Sulfonylisoindoline Derivatives as Liver-targeting Pyruvate Dehydrogenase Kinase Inhibitors, Shih-Chia Tso, Mingling Lou, Wen-Jun Gui, Cheng-Yang Wu, Jacinta L. Chuang, Lorraine K. Morlock, Noelle S. Williams, R. Max Wynn, Xiangbing Qi, David T. Chuang, 2017
- Reciprocal Regulation between the Circadian Clock and Hypoxia Signaling at the Genome Level in Mammals, Yaling Wu, Dingbin Tang, Na Liu, Wei Xiong, Huanwei Huang, Yang Li, Zhixiong Ma, Haijiao Zhao, Peihao Chen, Xiangbing Qi, Eric Erquan Zhang, 2017
- Structure-based Design and Mechanisms of Allosteric Inhibitors for Mitochondrial Branched-chain α-Ketoacid Dehydrogenase Kinase, Shih-chia Tso, Xiangbing Qi, Wen-Jun Gui, Jacinta L. Chuang, Lorraine K. Morlock, Amy L. Wallace, Kamran Ahmed, Sunil Laxman, Philippe M. Campeau, Brendan H. Lee, Susan M. Hutson, Benjamin P. Tu, Noelle S. Williams, Uttam K. Tambar, R. Max Wynna, David T. Chuang, 2013
- Allenes in Asymmetric Catalysis: Asymmetric Addition of Boronic Acid to α-ketoesters Catalyzed by Allene-Containing Rhodium-Phosphine Catalyst, Feng Cai, Xiaotao Pu, Xiangbing Qi, Joseph. M. Ready, 2011
- Total Synthesis of (±)-Trigonoliimine C via Oxidative Rearrangement of an Unsymmetrical Bis-Tryptamine, Xiangbing Qi, Hongli Bao, Uttam K.Tambar, 2011
- Catalytic Enantioselective [2,3]-Rearrangements of Amine N-Oxides, Hongli Bao, Xiangbing Qi, Uttam K.Tambar, 2011
- Diversification of a β-lactam Pharmacophore via Allylic C–H Amination: Accelerating Effect of Lewis Acid co-catalyst, Xiangbing Qi, Grant T. Rice, Manjinder S. Lall, Mark S. Plummer, M. Christina White, 2010
- Allenes in Asymmetric Catalysis: Asymmetric Ring Opening of meso-Epoxides Catalyzed by Allene-Containing Phosphine Oxides, Xiaotao Pu, Xiangbing Qi, Joseph. M. Ready, 2009
- Synthesis of Cyclopentenones from Cyclopropanes and Silyl Ynol Ethers, Xiangbing Qi, Joseph. M. Ready, 2008
- Copper-Promoted Cycloaddition of Diazocarbonyl Compounds with Copper Acetylides, Xiangbing Qi, Joseph. M. Ready, 2007
