Professor | 李毅 | 数字化转型顾问

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Name	李毅
Contact Information	liyi@@ion.ac.cn
Language ability	中文, 英语
Province	上海

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Name

李毅

Contact Information

liyi@@ion.ac.cn

Language ability

中文, 英语

Province

上海

University/Lab Affiliation and Title	中国科学院
Faculty	institute of neuroscience Chinese academy of sciences
Academic Background & Achievements	2007 - 医学学士学位: 东南大学 2013 - 遗传学博士学位: 东南大学
Work Experience	2014-2020 - 博士后研究: 哈佛大学医学院附属波士顿儿童医院 2021-至今 - 研究员及研究组组长: 中国科学院脑科学与智能技术卓越创新中心

University/Lab Affiliation and Title

中国科学院

Faculty

institute of neuroscience Chinese academy of sciences

Academic Background & Achievements

2007 - 医学学士学位: 东南大学
2013 - 遗传学博士学位: 东南大学

Work Experience

2014-2020 - 博士后研究: 哈佛大学医学院附属波士顿儿童医院
2021-至今 - 研究员及研究组组长: 中国科学院脑科学与智能技术卓越创新中心

Areas of Focus	中枢神经系统损伤与修复轴突再生组织修复沉默神经环路的重新激活脑机接口
Publications	Actomyosin-II Protects Axons from Degeneration Induced by Mild Mechanical Stress, Pan X, Hu Y, Lei G, Wei Y, Li J, Luan T, Zhang Y, Chu Y, Feng Y, Zhan W, Zhao C, Meunier F, Liu Y, Li Y and Wang T, 2024 Gliotransmission and adenosine signaling promote axon regeneration, Wang, F., Ruppell, K., Zhou, S., Qu, Y., Gong, J., Shang, Y., Wu, J., Liu, X., Diao, W., Li Y, Xiang, Y., 2023 Microglia coordinate cellular interactions during spinal cord repair in mice, Faith H. Brennan, Yang Li, Cankun Wang, Anjun Ma, Li Y, Nicole Pukos, Warren A. Campbell, Kristina G. Witcher, Zhen Guan, Kristina A. Kigerl, Jodie C.E. Hall Jonathan P. Godbout, Andy J. Fischer, Dana M. McTigue, Zhigang He, Qin Ma, and Phillip G. Popovich, 2022 Microglia-organized Scar-free spinal cord repair in neonatal mice, Li Y, He X, Kawaguchi R, Zhang Y, Wang Q, Monavarfeshani A, Yang Z, Chen B, Shi Z, Meng H, Zhou S, Zhu J, Jacobi A, Swarup V, Popovich P, Geschwind D, He Z, 2020 Robust Myelination of Regenerated Axons Induced by Combined Manipulations of GPR17 and Microglia, Wang J, He X, Meng H, Li Y, Dmitriev P, Tian F, Page J, Lu Q, He Z, 2020 Neuronal deletion of Gtf2i, associated with Williams syndrome, causes behavioral and myelin alterations rescuable by a remyelinating drug, Boaz Barak, Zicong Zhang, Yuanyuan Liu, Ariel Nir, Sari S Trangle, Michaela Ennis, Kirsten M Levandowski, Dongqing Wang, Kathleen Quast, Gabriella L Boulting, Li Y, Dashzeveg Bayarsaihan, Zhigang He, Guoping Feng, 2019 Reactivation of Dormant Relay Pathways in Injured Spinal Cord by KCC2 Manipulations, Chen B, Li Y, Yu B, Zhang Z, Brommer B, Williams, P.R, Liu Y, Hegarty, S. V, Zhu, S, Zhu, J, Guo, H, Lu, Y, Gu, X, and He, Z, 2018 A Sensitized IGF1 Treatment Restores Corticospinal Axon-Dependent Functions, Liu Y, Wang X, Li W, Zhang Q, Li Y, Zhang Z, Zhu J, Chen B, Williams PR, Zhang Y, Yu B, Gu X, He Z, 2017 Sox11 Expression Promotes Regeneration of Some Retinal Ganglion Cell Types but Kills Others, Norsworthy MW, Bei F, Kawaguchi R, Wang Q, Tran NM, Li Y, Brommer B, Zhang Y, Wang C, Sanes JR, Coppola G, He Z, 2017 Fbxl4 Serves as a Clock Output Molecule that Regulates Sleep through Promotion of Rhythmic Degradation of the GABAA Receptor, Li Q, Li Y, Wang X, Qi J, Jin X, Tong H, Zhou Z, Zhang ZC, Han J, 2017 Neurexin regulates nighttime sleep by modulating synaptic transmission, Tong H, Li Q, Zhang ZC, Li Y, Han J, 2017 Drosophila neuroligin 4 regulates sleep through modulating GABA transmission, Li Y, Zhou Z, Zhang X, Tong H, Li P, Zhang ZC, Jia Z, Xie W, Han J, 2013 A Drosophila metallophosphoesterase mediates deglycosylation of rhodopsin, Cao J, Li Y, Xia W, Reddig K, Hu W, Xie W, Li HS, Han J, 2011

Areas of Focus

中枢神经系统损伤与修复
轴突再生
组织修复
沉默神经环路的重新激活
脑机接口

Publications

Actomyosin-II Protects Axons from Degeneration Induced by Mild Mechanical Stress, Pan X, Hu Y, Lei G, Wei Y, Li J, Luan T, Zhang Y, Chu Y, Feng Y, Zhan W, Zhao C, Meunier F, Liu Y, Li Y and Wang T, 2024
Gliotransmission and adenosine signaling promote axon regeneration, Wang, F., Ruppell, K., Zhou, S., Qu, Y., Gong, J., Shang, Y., Wu, J., Liu, X., Diao, W., Li Y, Xiang, Y., 2023
Microglia coordinate cellular interactions during spinal cord repair in mice, Faith H. Brennan, Yang Li, Cankun Wang, Anjun Ma, Li Y, Nicole Pukos, Warren A. Campbell, Kristina G. Witcher, Zhen Guan, Kristina A. Kigerl, Jodie C.E. Hall Jonathan P. Godbout, Andy J. Fischer, Dana M. McTigue, Zhigang He, Qin Ma, and Phillip G. Popovich, 2022
Microglia-organized Scar-free spinal cord repair in neonatal mice, Li Y, He X, Kawaguchi R, Zhang Y, Wang Q, Monavarfeshani A, Yang Z, Chen B, Shi Z, Meng H, Zhou S, Zhu J, Jacobi A, Swarup V, Popovich P, Geschwind D, He Z, 2020
Robust Myelination of Regenerated Axons Induced by Combined Manipulations of GPR17 and Microglia, Wang J, He X, Meng H, Li Y, Dmitriev P, Tian F, Page J, Lu Q, He Z, 2020
Neuronal deletion of Gtf2i, associated with Williams syndrome, causes behavioral and myelin alterations rescuable by a remyelinating drug, Boaz Barak, Zicong Zhang, Yuanyuan Liu, Ariel Nir, Sari S Trangle, Michaela Ennis, Kirsten M Levandowski, Dongqing Wang, Kathleen Quast, Gabriella L Boulting, Li Y, Dashzeveg Bayarsaihan, Zhigang He, Guoping Feng, 2019
Reactivation of Dormant Relay Pathways in Injured Spinal Cord by KCC2 Manipulations, Chen B, Li Y, Yu B, Zhang Z, Brommer B, Williams, P.R, Liu Y, Hegarty, S. V, Zhu, S, Zhu, J, Guo, H, Lu, Y, Gu, X, and He, Z, 2018
A Sensitized IGF1 Treatment Restores Corticospinal Axon-Dependent Functions, Liu Y, Wang X, Li W, Zhang Q, Li Y, Zhang Z, Zhu J, Chen B, Williams PR, Zhang Y, Yu B, Gu X, He Z, 2017
Sox11 Expression Promotes Regeneration of Some Retinal Ganglion Cell Types but Kills Others, Norsworthy MW, Bei F, Kawaguchi R, Wang Q, Tran NM, Li Y, Brommer B, Zhang Y, Wang C, Sanes JR, Coppola G, He Z, 2017
Fbxl4 Serves as a Clock Output Molecule that Regulates Sleep through Promotion of Rhythmic Degradation of the GABAA Receptor, Li Q, Li Y, Wang X, Qi J, Jin X, Tong H, Zhou Z, Zhang ZC, Han J, 2017
Neurexin regulates nighttime sleep by modulating synaptic transmission, Tong H, Li Q, Zhang ZC, Li Y, Han J, 2017
Drosophila neuroligin 4 regulates sleep through modulating GABA transmission, Li Y, Zhou Z, Zhang X, Tong H, Li P, Zhang ZC, Jia Z, Xie W, Han J, 2013
A Drosophila metallophosphoesterase mediates deglycosylation of rhodopsin, Cao J, Li Y, Xia W, Reddig K, Hu W, Xie W, Li HS, Han J, 2011

神经科学脊髓损伤中风创伤性脑损伤基因治疗细胞治疗轴突再生组织修复神经环路脑机接口

周海波 - 中国科学院

蒲慕明 - 中国科学院

孙衍刚 - 中国科学院

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