Professor | 徐伟 | 数字化转型顾问

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Name	徐伟
Contact Information	wxu29@cqmu.edu.cn
Language ability	英语, 中文
Province	重庆

Upload Avatar (500 x 500)

Name

徐伟

Contact Information

wxu29@cqmu.edu.cn

Language ability

英语, 中文

Province

重庆

University/Lab Affiliation and Title	重庆医科大学
Faculty	Basic Medical Sciences
Academic Background & Achievements	2009.09-2013.07 理学学士（药学专业）：北京大学 2010.09-2013.07 经济学学士（双学位）：北京大学 2013.09-2015.07 理学硕士（化学生物学专业）：北京大学 2015.08-2021.04 博士（药理学与分子科学专业）：约翰霍普金斯大学以第一作者身份在《Nature》、《Acta Pharmaceutica Sinica B》、《Cell Reports》发表论文
Work Experience	2015.08-2021.04 - 约翰霍普金斯大学 - 博士研究 2021.04-2022.01 - 约翰霍普金斯大学 - 博士后研究 2022.03-2024.02 - 天科雅生物科技有限公司 - 研发员 2024.02-至今 - 重庆医科大学 - 特聘教授

University/Lab Affiliation and Title

重庆医科大学

Faculty

Basic Medical Sciences

Academic Background & Achievements

2009.09-2013.07 理学学士（药学专业）：北京大学
2010.09-2013.07 经济学学士（双学位）：北京大学
2013.09-2015.07 理学硕士（化学生物学专业）：北京大学
2015.08-2021.04 博士（药理学与分子科学专业）：约翰霍普金斯大学
以第一作者身份在《Nature》、《Acta Pharmaceutica Sinica B》、《Cell Reports》发表论文

Work Experience

2015.08-2021.04 - 约翰霍普金斯大学 - 博士研究
2021.04-2022.01 - 约翰霍普金斯大学 - 博士后研究
2022.03-2024.02 - 天科雅生物科技有限公司 - 研发员
2024.02-至今 - 重庆医科大学 - 特聘教授

Areas of Focus	代谢调控免疫细胞功能与分化的分子机制
Publications	GOT1 constrains TH17 cell and promotes Treg cell differentiation., Wei Xu, Chirag H. Patel, Jesse Alt, Liang Zhao, Im-Hong Sun, Min-Hee Oh, Im-Meng Sun, Jiayu Wen, Richard L. Blosser, Ada J. Tam, Jonathan D. Powell, 2023 GOT1 regulates CD8+ effector and memory T cell generation., Wei Xu, Chirag H. Patel, Liang Zhao, Im-Hong Sun, Min-Hee Oh, Im-Meng Sun, Rachel Helms, Jiayu Wen, Jonathan D. Powell, 2023 Peeking under the hood of naive T cells., Wei Xu, Jonathan D. Powell, 2018 Factors to consider in developing individual pharmaceutical product quality risk profiles useful to government procurement agencies., Wei Xu, Boehm Garth, Qiang Zheng, 2016 Synergism between thioredoxin reductase inhibitor ethaselen and sodium selenite in inhibiting proliferation and inducing death of human non-small cell lung cancer cells., Xiaoqing Zheng, Wei Xu, Ruoxuan Sun, Hanwei Yin, Chaoran Dong, Huihui Zeng, 2017 A tunable brake for HECT ubiquitin ligases., Zan Chen, Hanjie Jiang, Wei Xu, Xiaoguang Li, Daniel R. Dempsey, Xiangbin Zhang, Peter Devreotes, Cynthia Wolberger, L. Mario Amzel, Sandra B. Gabelli, Philip A. Cole, 2017 mTORC2 regulates CD8+ effector and memory T cell differentiation through serum and glucocorticoid kinase 1., Chirag H. Patel, Emily B. Heikamp, Wei Xu, Im-Hong Sun, Min-Hee Oh, Im-Meng Sun, Jiayu Wen, Ada J. Tam, Richard L. Blosser, Jonathan D. Powell, 2022 Modulation of p300/CBP acetylation of nucleosomes by bromodomain ligand I-CBP112., Beth E Zucconi, Birgit Luef, Wei Xu, Ryan A. Henry, Ilana M. Nodelman, Gregory D. Bowman, Andrew J. Andrews, Philip A. Cole, 2016 Targeting glutamine metabolism enhances tumor-specific immunity by modulating suppressive myeloid cells., Min-Hee Oh, Im-Hong Sun, Liang Zhao, Robert D. Leone, Im-Meng Sun, Wei Xu, Samuel L. Collins, Ada J. Tam, Richard L. Blosser, Chirag H. Patel, Judson M. Englert, Matthew L. Arwood, Jiayu Wen, Yee Chan-Li, Lukáš Tenora, Pavel Majer, Rana Rais, Barbara S. Slusher, Maureen R. Horton, Jonathan D. Powell, 2020 mTOR complex 1 signaling regulates the generation and function of central and effector Foxp3+ regulatory T cells., Im-Hong Sun, Min-Hee Oh, Liang Zhao, Chirag H. Patel, Matthew L. Arwood, Wei Xu, Ada J. Tam, Richard L. Blosser, Jiayu Wen, Jonathan D. Powell, 2018

Areas of Focus

代谢调控免疫细胞功能与分化的分子机制

Publications

GOT1 constrains TH17 cell and promotes Treg cell differentiation., Wei Xu, Chirag H. Patel, Jesse Alt, Liang Zhao, Im-Hong Sun, Min-Hee Oh, Im-Meng Sun, Jiayu Wen, Richard L. Blosser, Ada J. Tam, Jonathan D. Powell, 2023
GOT1 regulates CD8+ effector and memory T cell generation., Wei Xu, Chirag H. Patel, Liang Zhao, Im-Hong Sun, Min-Hee Oh, Im-Meng Sun, Rachel Helms, Jiayu Wen, Jonathan D. Powell, 2023
Peeking under the hood of naive T cells., Wei Xu, Jonathan D. Powell, 2018
Factors to consider in developing individual pharmaceutical product quality risk profiles useful to government procurement agencies., Wei Xu, Boehm Garth, Qiang Zheng, 2016
Synergism between thioredoxin reductase inhibitor ethaselen and sodium selenite in inhibiting proliferation and inducing death of human non-small cell lung cancer cells., Xiaoqing Zheng, Wei Xu, Ruoxuan Sun, Hanwei Yin, Chaoran Dong, Huihui Zeng, 2017
A tunable brake for HECT ubiquitin ligases., Zan Chen, Hanjie Jiang, Wei Xu, Xiaoguang Li, Daniel R. Dempsey, Xiangbin Zhang, Peter Devreotes, Cynthia Wolberger, L. Mario Amzel, Sandra B. Gabelli, Philip A. Cole, 2017
mTORC2 regulates CD8+ effector and memory T cell differentiation through serum and glucocorticoid kinase 1., Chirag H. Patel, Emily B. Heikamp, Wei Xu, Im-Hong Sun, Min-Hee Oh, Im-Meng Sun, Jiayu Wen, Ada J. Tam, Richard L. Blosser, Jonathan D. Powell, 2022
Modulation of p300/CBP acetylation of nucleosomes by bromodomain ligand I-CBP112., Beth E Zucconi, Birgit Luef, Wei Xu, Ryan A. Henry, Ilana M. Nodelman, Gregory D. Bowman, Andrew J. Andrews, Philip A. Cole, 2016
Targeting glutamine metabolism enhances tumor-specific immunity by modulating suppressive myeloid cells., Min-Hee Oh, Im-Hong Sun, Liang Zhao, Robert D. Leone, Im-Meng Sun, Wei Xu, Samuel L. Collins, Ada J. Tam, Richard L. Blosser, Chirag H. Patel, Judson M. Englert, Matthew L. Arwood, Jiayu Wen, Yee Chan-Li, Lukáš Tenora, Pavel Majer, Rana Rais, Barbara S. Slusher, Maureen R. Horton, Jonathan D. Powell, 2020
mTOR complex 1 signaling regulates the generation and function of central and effector Foxp3+ regulatory T cells., Im-Hong Sun, Min-Hee Oh, Liang Zhao, Chirag H. Patel, Matthew L. Arwood, Wei Xu, Ada J. Tam, Richard L. Blosser, Jiayu Wen, Jonathan D. Powell, 2018

代谢免疫细胞功能分化分子机制调控细胞代谢免疫反应生物化学分子生物学

王华 - 北京大学

葛青 - 北京大学

乐江 - 武汉大学

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