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王理
Bioinformatics Science and Technology
哈尔滨医科大学
黑龙江
Language: 中文, 英语
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肿瘤异质性 早期诊断 癌症治疗 预后 大数据 人工智能 转录组学 分子机制 免疫微环境 免疫治疗
Areas of Focus
  • 恶性肿瘤异质性解析
  • 早期诊断
  • 癌症治疗决策
  • 预后评估
  • 生物医学大数据
  • 人工智能
  • 单细胞及空间转录组学
  • 癌症演进分子机制
  • 肿瘤免疫微环境
  • 免疫治疗
Publications
  • LncTarD 2.0: an updated comprehensive database for experimentally-supported functional lncRNA-target regulations in human diseases., 王理, 2023
  • Comprehensive landscape of epigenetic-dysregulated lncRNAs reveals a profound role of enhancers in carcinogenesis in BC subtypes., 王理, 2021
  • LncTarD: a manually-curated database of experimentally-supported functional lncRNA-target regulations in human diseases., 王理, 2020
  • The dynamic dysregulated network identifies stage-specific markers during lung adenocarcinoma malignant progression and metastasis., 王理, 2022
  • Lnc2Cancer v2.0: updated database of experimentally supported long non-coding RNAs in human cancers., 王理, 2019
  • Identifying functions and prognostic biomarkers of network motifs marked by diverse chromatin states in human cell lines., 王理, 2020
  • Identifying tumour microenvironment-related signature that correlates with prognosis and immunotherapy response in breast cancer., 王理, 2023
  • Integrated analysis of single-cell and bulk RNA sequencing data reveals immune-related lncRNA-mRNA prognostic signature in triple-negative breast cancer., 王理, 2023
  • Identifying enhancer-driven subtype-specific prognostic markers in breast cancer based on multi-omics data., 王理, 2022
  • Comprehensive identification and potential application of genetic alteration-driven enhancer RNAs for eRNA-targeted therapy in breast cancer., 王理, 2023
  • Genome-wide DNA methylome analysis reveals a critical role of methylation-dysregulated lncRNAs in autophagy regulation in glioblastoma., 王理, 2023
  • Identification of somatic mutation-driven enhancers and their clinical utility in breast cancer., 王理, 2024
Awards
  • 黑龙江省高层次人才
  • 黑龙江省优青
  • 黑龙江省创新人才
  • 校级优秀科研工作者
  • 十佳青年岗位能手
  • 优秀教师
  • 五四青年奖章
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