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许雪梅
英语, 中文
北京
北京协和医学院
Basic Medical Sciences
  • 2002/12—2004/09: 美国芝加哥Loyola大学癌症研究中心访问学者
  • 1999/08—2002/07: 中国协和医科大学基础医学院博士学位
  • 1988/08—1991/07: 大连医科大学病理学硕士学位
  • 1983/09—1988/07: 山东医科大学医学学士学位
  • 1995/0—至今: 中国医学科学院基础医学研究所研究员和博士生导师
  • 1991/08—1995/07: 山东青岛第五人民医院病理科主治医师
HPV疫苗研究
HIV-1疫苗研究
Sars-CoV-2疫苗研究
疫苗佐剂
  • Induction of cross-neutralizing antibodies by sequential immunization with heterologous papillomavirus L1VLPs and its implications for HPV prophylactic vaccines., Ting Zhang, Xue Chen, Guoyang Liao, Meili Hu, Jianqing Xu, Xuemei Xu, 2020
  • A rationally designed flagellin-L2 fusion protein induced serum and mucosal neutralizing antibodies against multiple HPV types., Ting Zhang, Xue Chen, Hongyang Liu, Qifeng Bao, Zhirong Wang, Guoyang Liao, Xuemei Xu, 2019
  • HPV31 L1 C端截短基因可在昆虫细胞表达体系中高水平制备HPV L1疫苗., 郝亚茹,张婷,刘洪洋,王志荣,周艳,夏百成,许雪梅, 2019
  • Displaying 31RG-1 peptide on the surface of HPV16 L1 by use of a human papillomavirus chimeric virus-like particle induces cross-neutralizing antibody responses in mice., Xue Chen, Ting Zhang, Hongyang Liu, Yaru Hao, Guoyang Liao, Xuemei Xu, 2018
  • 一种可诱发高滴度的针对人乳头瘤病毒HPV16,HPV52,HPV58中和抗体反应的HPV16嵌合病毒样颗粒疫苗的研究., 陈雪,王志荣,刘洪洋,张婷,许雪梅, 2018
  • Human papillomavirus 16L1-58L2 chimeric virus-like particles elicit durable neutralizing antibody responses against a broad-spectrum of human papillomavirus types., Xue Chen, Hongyang Liu, Zhirong Wang, Shuo Wang, Ting Zhang, Meili Hu, Liang Qiao, Xuemei Xu, 2017
  • HPV 31型L2保守中和表位可诱发广谱中和抗体., 张婷,陈雪,刘洪洋,周艳,王志荣,许雪梅, 2017
  • Lipidated L2 epitope repeats fused with a single-chain antibody fragment targeting human Fc gamma RI elicited cross-neutralizing antibodies against a broad spectrum of human papillomavirus types., Ting Zhang, Hongyang Liu, Xue Chen, Zhirong Wang, Shuo Wang, Chunfeng Qu, Jingzhi Zhang, Xuemei Xu, 2016
  • A Vaccine of L2 Epitope Repeats Fused with a Modified IgG1 Fc Induced Broadly Cross-Neutralizing Antibodies and Protective Immunities against Divergent Human Papillomavirus., Xue Chen, Hongyang Liu, Ting Zhang, Yanchun Liu, Xixiu Xie, Zhirong Wang, Xuemei Xu, 2014
  • HSP70 and modified HPV 16 E7 fusion gene without the addition of a signal peptide gene sequence as a candidate therapeutic tumor vaccine., Jinbao Zong, Changyuan Wang, Qingyong Wang, Qinglin Peng, Yufei Xu, Xixiu Xie, Xuemei Xu, 2013
  • The immune complex CTA1-DD/IgG adjuvant specifically targets connective tissue mast cells through FcγRIIIA and augments anti-HPV immunity after nasal immunization., Yu Fang, Ting Zhang, Linnea Lidell, Xuemei Xu, Nils Lycke and Zou Xiang, 2013
  • Human papillomavirus type 58 L1 virus-like particles purified by two-step chromatography elicit high levels of long-lasting neutralizing antibodies., Xixiu Xie, Yanchun Liu, Ting Zhang, Yanying Xu, Qifeng Bao, Xue Chen, Hongyang Liu, Xuemei Xu, 2012
  • Comparison of Two High-Throughput Assays for Quantification of Adenovirus Type 5 Neutralizing Antibodies in a Population of Donors in China., Qiang Liu, Jianhui Nie, Weijin Huang, Shufang Meng, Baozhu Yuan, Dongying Gao, Xuemei Xu, Youchun Wang, 2012
  • Trivalent Human Papillomavirus (HPV) VLP vaccine covering HPV type 58 can elicit high level of humoral immunity but also induce interference among component types., Ting Zhang, Yufei Xu, Liang Qiao, Youchun Wang, Xueling Wu, Dongsheng Fan, Qinglin Peng, Xuemei Xu, 2010
  • Deglycosylation of HIV-1 AE Gp140 enhance the capacity to elicit neutralizing antibodies agains the heterologous HIV-1 clade., Congyou Zhang, Yanmin Wan, Shi jinhong, Xuemei Xu, Jianqing Xu, 2010
  • Human HSP70 and modified HPV16 E7 fusion DNA vaccine induces enhanced specific CD8+T cell responses and anti-tumor effects., Jinbao Zong, Qinglin Peng, Qingyong Wang, Ting Zhang, Dongsheng Fan, Xuemei Xu, 2009
  • Human papillomaviruses and cervical vaccines: To decode 2008 Nobel Prize in physiology or medicine., Xuemei Xu, 2008
  • Enhancement of vaccine potency by fusing modified LTK63 into human papillomavirus type 16 chimeric virus-like particles., Yufei Xu, Hongtao Zhang, Xuemei Xu, 2008
  • The type-specific and cross-reactive neutralizing antibodies induce by human papillomavirus type 31 L1/L2 Virus-like Particles., Yufei Xu, Qingyong Wang, Xuemei Xu, 2007
  • Encapsidating artificial human papillomavirus-16 mE7 protein in human papillomavirus-6b L1/L2 virus like particles., Yufei Xu, Qingyong Wang, Hongtao Zhang, Yehua Han, Xuemei Xu, 2007
  • The efficacy a DNA vaccine containing inserted and replicated regions of the E7 gene for treatment of HPV 16 induced tumors., Joeli A. Brinkman, Xuemei Xu, W. Martin Kast, 2007
Hpv 疫苗 中和抗体 基因工程 嵌合Vlp 交叉中和 Hiv-1 Sars-Cov-2 佐剂 免疫治疗

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