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张卫奇
中文, 英语
北京
北京协和医学院
Basic Medical Sciences
  • 2004.09-2008.07 生物技术学士学位:湖南师范大学
  • 2008.09-2013.07 生物医学工程博士学位:北京协和医学院
  • 在专业期刊发表论文35篇
  • 2014.02-2018.12 - 康奈尔大学医学院 - 放射医学系博士后研究
  • 2019.02至今 - 中国医学科学院基础医学研究所&北京协和医学院 - 课题组长
  • 北京市科技新星计划
  • 中国医学科学院创新工程子课题
  • 协和青年基金
  • 国家重点实验室自主课题
药物递送与分子影像
  • Tailoring the surface charges of iron-crosslinked dextran nanogels towards improved tumor-associated macrophage targeting, Hong Deng, Xue Yang, Huimin Wang, Menghan Gao, Yiyi Zhang, Runmeng Liu, Haiyan Xu*, Weiqi Zhang*, 2024
  • Hyaluronan nanogel co-loaded with chloroquine to enhance intracellular cisplatin delivery through lysosomal permeabilization and lysophagy inhibition, Menghan Gao, Hong Deng, Yiyi Zhang, Huimin Wang, Runmeng Liu, Wei Hou, Weiqi Zhang*, 2024
  • Radiotherapy Potentiates the P-Selectin Targeted Cancer Drug Delivery Based on a Cisplatin and Mitoxantrone Coassembled Fucoidan Nanogel, Huimin Wang, Hong Deng, Menghan Gao, Yiyi Zhang, Runmeng Liu, Wei Hou, Haiyan Xu*, and Weiqi Zhang*, 2023
  • Facile preparation of toluidine blue-loaded DNA nanogels for anticancer photodynamic therapy, Hua Guo#, Huimin Wang#, Hong Deng, Yiyi Zhang, Xue Yang*, Weiqi Zhang*, 2023
  • A hybrid nanogel to preserve lysosome integrity for fluorescence imaging, Weiqi Zhang*, Baoji Du, Menghan Gao, Ching-Hsuan Tung*, 2021
  • Self-assembled nanogels based on ionic gelation of natural polysaccharides for drug delivery, Huimin Wang, Hong Deng, Menghan Gao, Weiqi Zhang*, 2021
  • Hyaluronan based multifunctional nano-carriers for combination cancer therapy, Menghan Gao, Hong Deng, Weiqi Zhang*, 2021
  • Co-delivery of homoharringtonine and doxorubicin boosts therapeutic efficacy of refractory acute myeloid leukemia, Doudou Yan#, Hui Wei#, Xinning Lai, Yangyang Ge, Shilin Xu, Jie Meng, Tao Wen, Jian Liu, Weiqi Zhang*, Jianxiang Wang*, Haiyan Xu*, 2020
  • Stiffness of cationized gelatin nanoparticles is a key factor determining RNAi efficiency in myeloid leukemia cells, Weiqi Zhang#, Bo Han#, Xinning Lai, Chen Xiao, Shilin Xu, Xianghui Meng, Zifu Li, Jie Meng, Tao Wen, Xiangliang Yang, Jian Liu, Haiyan Xu, 2020
  • Lysosome enlargement enhanced photochemotherapy using a multifunctional nanogel, Weiqi Zhang, Ching-Hsuan Tung, 2018
  • Redox-responsive cisplatin nanogel for anticancer drug delivery, Weiqi Zhang, Ching-Hsuan Tung, 2018
  • Real-time visualization of lysosome destruction using a photosensitive toluidine blue nanogel, Weiqi Zhang, Ching-Hsuan Tung, 2018
  • Ratio of polycations and serum is a crucial index determining the RNAi efficiency of polyplexes, Weiqi Zhang#, Xianghui Meng#, Huike Liu, Lifei Xie, Jian Liu, Haiyan Xu, 2017
  • Sequence-independent DNA nanogel as a potential drug carrier, Weiqi Zhang, Ching-Hsuan Tung, 2017
  • Cisplatin cross-linked multifunctional nanodrugplexes for combination therapy, Weiqi Zhang, Ching-Hsuan Tung, 2017
  • Beyond chemotherapeutics: cisplatin as a temporary buckle to fabricate drug-loaded nanogels, Weiqi Zhang, Zhe Zhang, Ching-Hsuan Tung, 2017
  • The effect of serum in culture on RNAi efficacy through modulation of polyplexes size, Weiqi Zhang#, Jian Liu#, Yasuhiko Tabata, Jie Meng, Haiyan Xu, 2014
  • Trafficking of gold nanorods in breast cancer cells: uptake, lysosome maturation and elimination, Weiqi Zhang, Yinglu Ji, Xiaochun Wu, Haiyan Xu, 2013
  • Probing the behaviors of gold nanorods in metastatic breast cancer cells based on UV-vis-NIR absorption spectroscopy, Weiqi Zhang, Yinglu Ji, Jie Meng, Xiaochun Wu, Haiyan Xu, 2012
  • Inhibiting metastasis of breast cancer cells in vitro using gold nanorod-siRNA delivery system, Weiqi Zhang#, Jie Meng#, Yinglu Ji, Xiaojin Li, Hua Kong, Xiaochun Wu, Haiyan Xu, 2011
  • Revealing silver cytotoxicity using Au Nanorods/Ag shell nanostructures: disrupting cell membrane and causing apoptosis through oxidative damage, Xuelian Cheng#, Weiqi Zhang#, Yinglu Ji, Jie Meng, Hua Guo, Jian Liu, Xiaochun Wu, Haiyan Xu, 2013
  • Tailoring the RNAi efficiency of polyplexes, Weiqi Zhang, Haiyan Xu, 2014
  • As4S4 nanoparticles promote effective terminal erythropoiesis in bone marrow mononuclear cells from patients with myelodysplastic syndromes, Tao Wang, Weiqi Zhang, Wanshu Chen, Jie Meng, Qinglin Hu, Jian Liu, Tao Wen, Bing Han, Haiyan Xu, 2023
  • A novel CD123-targeted therapeutic peptide loaded by micellar delivery system combats refractory acute myeloid leukemia, Shilin Xu, Meichen Zhang, Xiaocui Fang, Jie Meng, Haiyan Xing, Doudou Yan, Jian Liu, Yanlian Yang, Tao Wen, Weiqi Zhang, Jianxiang Wang, Chen Wang, Haiyan Xu, 2021
  • Multilayered activatable nanoprobe for ultra-bright tumor imaging, Seung Koo Lee, Myung Shin Han, Weiqi Zhang, Ching-Hsuan Tung, 2019
  • A multiresponsive nanohybrid to enhance the lysosomal delivery of oxygen and photosensitizers, Baoji Du, Weiqi Zhang, Ching-Hsuan Tung, 2019
  • An [18F]-positron emitting fluorophore allows safe evaluation of small molecule distribution in the CSF, CSF Fistulas, and CNS device placement, Hua Guo, Harikrishna Kommidi, Uday B Maachani, Julia C Voronina, Weiqi Zhang, Rajiv S Magge, Jana Ivanidze, Amy P Wu, Mark M Souweidane, Omer Aras, Richard Ting, 2019
  • A fluorescent, [18F]-positron-emitting agent for imaging prostate-specific membrane antigen allows genetic reporting in adoptively transferred, genetically modified cells, Hua Guo, Harikrishna Kommidi, Yogindra Vedvyas, Jaclyn E McCloskey, Weiqi Zhang, Nandi Chen, Fuad Nurili, Amy P Wu, Haluk B Sayman, Oguz Akin, Erik A Rodriguez, Omer Aras, Moonsoo M Jin, Richard Ting, 2019
  • Layer-by-layer construction of an oxygen-generating photo-responsive nanomedicine for enhanced photothermal and photodynamic combination therapy, Baoji Du, Weiqi Zhang, Ching-Hsuan Tung, 2019
  • Facile metabolic glycan labeling strategy for exosome tracking, Tae Sup Lee, Young Kim, Weiqi Zhang, In Ho Song, Ching-Hsuan Tung, 2018
  • Modulating the growth and imatinib sensitivity of chronic myeloid leukemia stem/progenitor cells with pullulan/microRNA nanoparticles in vitro, Wenjuan Ma, Jian Liu, Jundan Xie, Xiuyan Zhang, Haixia Zhou, Hong Yao, Weiqi Zhang, Dawei Guo, Lingying Zhu, Lun Xiao, Depei Wu, Haiyan Xu, Suning Chen, Yun Zhao, 2015
  • Using gold nanorods core/silver shell nanostructures as model material to probe biodistribution and toxic effects of silver nanoparticles in mice, Jie Meng, Yinglu Ji, Jian Liu, Xuelian Cheng, Hua Guo, Weiqi Zhang, Xiaochun Wu, Haiyan Xu, 2014
  • Effects of long and short carboxylated or aminated multiwalled carbon nanotubes on blood coagulation, Jie Meng, Xuelian Cheng, Jian Liu, Weiqi Zhang, Xiaojin Li, Hua Kong, Haiyan Xu, 2012
  • Multiwalled carbon nanotubes interact with macrophages and influence tumor progression and metastasis, Man Yang, Jie Meng, Xuelian Cheng, Jing Lei, Hua Guo, Weiqi Zhang, Hua Kong, Haiyan Xu, 2012
  • Subcutaneous injection of water-soluble multi-walled carbon nanotubes in tumor-bearing mice boosts the host immune activity, Jie Meng, Man Yang, Fumin Jia, Hua Kong, Weiqi Zhang, Chaoying Wang, Jianmin Xing, Sishen Xie, Haiyan Xu, 2010
纳米医学 药物递送 分子影像 癌症治疗 纳米材料 生物医学工程 肿瘤成像 纳米载体 生物物理学 药理学

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