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彭慧
Basic Medical Sciences
中国科学技术大学
安徽
Language: 中文, 英语
Nk细胞
Ilc亚群
发育
分化
免疫特性
区域免疫
重大疾病
机制
肝脏
免疫学
Areas of Focus
- NK细胞和ILC亚群发育分化
- NK细胞/ILC1的区域免疫特性
- NK细胞/ILC1在重大疾病中的作用及机制
Work Experience
- 2012-2014 - 中国科学技术大学 - 博士后研究
- 2014-2019 - 中国科学技术大学 - 特任副研究员、副教授
- 2019-至今 - 中国科学技术大学 - 特任教授
Academic Background & Achievements
- 2006 - 本科学位：中国科学技术大学
- 2012 - 博士学位：中国科学技术大学
- 成就：发现了肝脏驻留NK细胞新亚群
Publications
- RORα is required for expansion and memory maintenance of ILC1s via a lymph node-liver axis, Cheng M, Li J, Song J, Song H, Chen Y, Tang H, Wei H, Sun R, Tian Z, Wang X, Peng H, 2024
- A pan-cancer single-cell panorama of human natural killer cells, Tang F, Li J, Qi L, Liu D, Bo Y, Qin S, Miao Y, Yu K, Hou W, Li J, Peng J, Tian Z, Zhu L, Peng H, Wang D, Zhang Z, 2023
- Ly49E separates liver ILC1s into embryo-derived and postnatal subsets with different functions, Chen Y, Wang X, Hao X, Li B, Tao W, Zhu S, Qu K, Wei H, Sun R, Peng H, Tian Z, 2022
- Requirement of RORα for maintenance and antitumor immunity of liver-resident natural killer cells/ILC1s, Song J, Song H, Wei H, Sun R, Tian Z, Peng H, 2022
- Liver type 1 innate lymphoid cells develop locally via an interferon-γ-dependent loop, Bai L, Vienne M, Tang L, Kerdiles Y, Etiennot M, Escalière B, Galluso J, Wei H, Sun R, Vivier E, Peng H, Tian Z, 2021
- Tissue-resident memory-like ILCs: innate counterparts of TRM cells, Wang X, Tian Z, Peng H, 2020
- Immunological memory: ILC1s come into view, Chen Y, Tian Z, Peng H, 2019
- A novel spleen-resident immature NK cell subset and its maturation in a T-bet-dependent manner, Wang B, Zhou J, Chen Y, Wei H, Sun R, Tian Z, Peng H, 2019
- Liver-resident NK cells control antiviral activity of hepatic T cells via PD-1/PD-L1 axis, Zhou J, Peng H, Li K, Qu K, Wang B, Wu Y, Ye L, Dong Z, Wei H, Sun R, Tian Z, 2019
- CD8+ T Cells Promote Maturation of Liver-Resident NK Cells via the CD70-CD27 axis, Bai L, Peng H, Hao X, Tang L, Sun C, Zheng M, Liu F, Lian Z, Bai L, Wei H, Sun R, Tian Z, 2019
- Memory formation and long-term maintenance of IL-7Rα+ ILC1s via a lymph node-liver axis, Wang X, Peng H, Cong J, Wang X, Lian Z, Wei H, Sun R, Tian Z, 2018
- Generating CD8αα IELs from two sources of thymic precursors, Bai L, Peng H, 2018
- Diversity of tissue-resident NK cells, Peng H, Tian Z, 2017
- Differential phenotypic and functional properties of liver-resident NK cells and mucosal ILC1s, Tang L, Peng H, Zhou J, Chen Y, Wei H, Sun R, Yokoyama WM, Tian Z, 2016
- Re-examining the origin and function of liver-resident NK cells, Peng H, Tian Z, 2015
- Liver-resident NK cells confer adaptive immunity in skin-contact inflammation, Peng H, Jiang X, Chen Y, Sojka DK, Wei H, Gao X, Sun R, Yokoyama WM, Tian Z, 2013
- CD62L is critical for maturation and accumulation of murine hepatic NK cells in response to viral infection, Peng H, Sun R, Tang L, Wei H, Tian Z, 2013
Awards
- 国家自然科学二等奖
- 中国免疫学会青年学者奖
- 入选第一届中国科协青年人才托举工程
