Professor | 袁晶 | 数字化转型顾问

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Name	袁晶
Contact Information	yuanjing@xmu.edu.cn
Language ability	英语, 中文
Province	福建

Upload Avatar (500 x 500)

Name

袁晶

Contact Information

yuanjing@xmu.edu.cn

Language ability

英语, 中文

Province

福建

University/Lab Affiliation and Title	厦门大学
Faculty	Life Sciences
Academic Background & Achievements	2002年 - 生物学学士: 中国农业大学 2007年 - 生物化学与分子生物学博士: 中国农业大学 2012年 - 美国国立卫生研究院院长奖 2014年 - 863青年科学家资助 2015年 - 国家自然基金优秀青年基金资助 2023年 - 入选教育部国家级领军人才项目
Work Experience	2007-2012年 - 美国国立卫生研究院 - 博士后 2012年至今 - 厦门大学生命科学学院 - 教授
Awards	美国国立卫生研究院院长奖 (2012): 杰出贡献的认可福建省高校青年教师教学竞赛二等奖 (2018) 厦门大学“何宜慈讲座教授奖教金” (2021) 厦门大学“我最喜爱的十位老师” (2020) 厦门大学第十二届青年教师教学技能比赛特等奖 (2017)

University/Lab Affiliation and Title

厦门大学

Faculty

Life Sciences

Academic Background & Achievements

2002年 - 生物学学士: 中国农业大学
2007年 - 生物化学与分子生物学博士: 中国农业大学
2012年 - 美国国立卫生研究院院长奖
2014年 - 863青年科学家资助
2015年 - 国家自然基金优秀青年基金资助
2023年 - 入选教育部国家级领军人才项目

Work Experience

2007-2012年 - 美国国立卫生研究院 - 博士后
2012年至今 - 厦门大学生命科学学院 - 教授

Awards

美国国立卫生研究院院长奖 (2012): 杰出贡献的认可
福建省高校青年教师教学竞赛二等奖 (2018)
厦门大学“何宜慈讲座教授奖教金” (2021)
厦门大学“我最喜爱的十位老师” (2020)
厦门大学第十二届青年教师教学技能比赛特等奖 (2017)

Areas of Focus	疟原虫在按蚊中感染和寄生的分子细胞机制开发和优化疟原虫基因组编辑工具CRISPR/Cas9
Publications	A subpellicular microtubule dynein transport machinery regulates ookinete morphogenesis for mosquito transmission of Plasmodium yoelii, Bing Liu, Cong Liu, Zhenkui Li, Wenjia Liu, Huiting Cui, Jing Yuan, 2024 An axonemal intron splicing program sustains Plasmodium male development, Jiepeng Guan, Peijia Wu, Xiaoli Mo, Xiaolong Zhang, Wenqi Liang, Xiaoming Zhang, Lubin Jiang, Jian Li, Huiting Cui, Jing Yuan, 2024 Deaggregation of mutant Plasmodium yoelii de-ubiquitinase UBP1 alters MDR1 localization to confer multidrug resistance, Ruixue Xu, Lirong Lini, Zhiwei Jiao, Rui Liang, Yazhen Guo, Yixin Zhang, Xiaoxu Shang, Yuezhou Wang, Xu Wang, Luming Yao, Shengfa Liu, Xianming Deng, Jing Yuan, Xin-Zhuan, Jian Li, 2024 EB1 decoration of microtubule lattice facilitates spindle-kinetochore lateral attachment in Plasmodium male gametogenesis, Shuzhen Yang, Mengya Cai, Junjie Huang, Shengnan Zhang, Xiaoli Mo, Kai Jiang, Huiting Cui, Jing Yuan, 2023 Apical anchorage and stabilization of subpellicular microtubules by apical polar ring ensures Plasmodium ookinete infection in mosquito, Pengge Qian, Xu Wang, Cuirong Guan, Xin Fang, Mengya Cai, Chuan-qi Zhong, Yong Cui, Yanbin Li, Luming Yao, Huiting Cui, Kai Jiang, Jing Yuan, 2022 Inner membrane complex proteomics reveals a palmitoylation regulation critical for intraerythrocytic development of malaria parasite, Pengge Qian, Xu Wang, Chuan-Qi Zhong, Jiaxu Wang, Mengya Cai, Wang Nguitragool, Jian Li, Huiting Cui, Jing Yuan, 2022 5-methylcytosine modification by Plasmodium NSUN2 stabilizes mRNA and mediates the development of gametocytes, Meng Liu, Gangqiang Guo, Pengge Qian, Jianbing Mu, Binbin Lu, Xiaoqin He, Yanting Fan, Xiaomin Shang, Guang Yang, Shijun Shen, Wenju Liu, Liping Wang, Liang Gu, Quankai Mu, Xinyu Yu, Yuemeng Zhao, Richard Culleton, Jun Cao, Lubin Jiang, Thomas E Wellems, Jing Yuan, Cizhong Jiang, Qingfeng Zhang, 2022 A malaria parasite phospholipid flippase safeguards midgut traversal of ookinetes for mosquito transmission, Zhenke Yang, Yang Shi, Huiting Cui, Shuzhen Yang, Han Gao, Jing Yuan, 2021 Plasmodium transcription repressor AP2‐O3 regulates sex‐specific identity of gene expression in female gametocytes, Zhenkui Li, Huiting Cui, Jiepeng Guan, Cong Liu, Zhengang Yang, Jing Yuan, 2021 Generation of Plasmodium yoelii malaria parasite for conditional degradation of proteins, Chuanyuan Liu, Zhenke Yang, Mengya Cai, Yang Shi, Huiting Cui, Jing Yuan, 2021 A protein palmitoylation cascade regulates microtubule cytoskeleton integrity in Plasmodium, Xu Wang, Pengge Qian, Huiting Cui, Luming Yao, Jing Yuan, 2020 An intracellular membrane protein GEP1 regulates xanthurenic acid induced gametogenesis of malaria parasites, Yuanyuan Jiang, Jun Wei, Huiting Cui, Chuanyuan Liu, Yuan Zhi, ZhengZheng Jiang, Zhenkui Li, Shaoneng Li, Zhenke Yang, Xu Wang, Pengge Qian, Cui Zhang, Chuanqi Zhong, Xinzhuan Su, Jing Yuan, 2020 ISP1-anchored polarization of GCβ/CDC50A complex initiates malaria ookinete gliding motility, Han Gao, Zhenke Yang, Xu Wang, Pengge Qian, Renjie Hong, Xin Chen, Xinzhuan Su, Huiting Cui, Jing Yuan, 2018 Generation of Plasmodium yoelii malaria parasite carrying double fluorescence reporters in gametocytes, Cong Liu, Zhenkui Li, Yuanyuan Jiang, Huiting Cui, Jing Yuan, 2018 A Cas9 transgenic Plasmodium yoelii parasite for efficient gene editing, Pengge Qian, Xu Wang, Zhenke Yang, Zhenkui Li, Han Gao, XinZhuan Su, Huiting Cui, Jing Yuan, 2018 Systematic CRISPR-Cas9-Mediated Modifications of Plasmodium yoelii ApiAP2 Genes Reveal Functional Insights into Parasite Development, Cui Zhang, Zhenkui Li, Huiting Cui, Yuanyuan Jiang, Zhenke Yang, Xu Wang, Han Gao, Cong Liu, Shujia Zhang, XinZhuan Su, Jing Yuan, 2017 CRISPR/Cas9 mediated sequential editing of genes critical for ookinete motility in Plasmodium yoelii, Cui Zhang, Han Gao, Zhenke Yang, Yuanyuan Jiang, Zhenkui Li, Xu Wang, Bo Xiao, XinZhuan Su, Huiting Cui, Jing Yuan, 2017 Efficient Editing of Malaria Parasite Genome Using the CRISPR/Cas9 System, Cui Zhang, Bo Xiao, Yuanyuan Jiang, Yihua Zhao, Zhenkui Li, Han Gao, Yuan Ling, Jun Wei, Shaoneng Li, Mingke Lu, XinZhuan Su, Huiting Cui, Jing Yuan, 2014 Chemical genomic profiling for antimalarial therapies, response signatures and molecular targets, Jing Yuan, Ken Chih-Chien Cheng, Ronald Johnson, Ruili Huang, Sittiporn Pattaradilokrat, Anna Liu, Rajarshi Guha, David Fidock, James Inglese, Thomas E Wellems, Christopher Austin, Xinzhuan Su, 2011 Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum, Jing Yuan, Ronald L Johnson, Ruili Huang, Jennifer Wichterman, Hongying Jiang, Karen Hayton, David A Fidock, Thomas E Wellems, James Inglese, Christopher P Austin, Xinzhuan Su, 2009

Areas of Focus

疟原虫在按蚊中感染和寄生的分子细胞机制
开发和优化疟原虫基因组编辑工具CRISPR/Cas9

Publications

A subpellicular microtubule dynein transport machinery regulates ookinete morphogenesis for mosquito transmission of Plasmodium yoelii, Bing Liu, Cong Liu, Zhenkui Li, Wenjia Liu, Huiting Cui, Jing Yuan, 2024
An axonemal intron splicing program sustains Plasmodium male development, Jiepeng Guan, Peijia Wu, Xiaoli Mo, Xiaolong Zhang, Wenqi Liang, Xiaoming Zhang, Lubin Jiang, Jian Li, Huiting Cui, Jing Yuan, 2024
Deaggregation of mutant Plasmodium yoelii de-ubiquitinase UBP1 alters MDR1 localization to confer multidrug resistance, Ruixue Xu, Lirong Lini, Zhiwei Jiao, Rui Liang, Yazhen Guo, Yixin Zhang, Xiaoxu Shang, Yuezhou Wang, Xu Wang, Luming Yao, Shengfa Liu, Xianming Deng, Jing Yuan, Xin-Zhuan, Jian Li, 2024
EB1 decoration of microtubule lattice facilitates spindle-kinetochore lateral attachment in Plasmodium male gametogenesis, Shuzhen Yang, Mengya Cai, Junjie Huang, Shengnan Zhang, Xiaoli Mo, Kai Jiang, Huiting Cui, Jing Yuan, 2023
Apical anchorage and stabilization of subpellicular microtubules by apical polar ring ensures Plasmodium ookinete infection in mosquito, Pengge Qian, Xu Wang, Cuirong Guan, Xin Fang, Mengya Cai, Chuan-qi Zhong, Yong Cui, Yanbin Li, Luming Yao, Huiting Cui, Kai Jiang, Jing Yuan, 2022
Inner membrane complex proteomics reveals a palmitoylation regulation critical for intraerythrocytic development of malaria parasite, Pengge Qian, Xu Wang, Chuan-Qi Zhong, Jiaxu Wang, Mengya Cai, Wang Nguitragool, Jian Li, Huiting Cui, Jing Yuan, 2022
5-methylcytosine modification by Plasmodium NSUN2 stabilizes mRNA and mediates the development of gametocytes, Meng Liu, Gangqiang Guo, Pengge Qian, Jianbing Mu, Binbin Lu, Xiaoqin He, Yanting Fan, Xiaomin Shang, Guang Yang, Shijun Shen, Wenju Liu, Liping Wang, Liang Gu, Quankai Mu, Xinyu Yu, Yuemeng Zhao, Richard Culleton, Jun Cao, Lubin Jiang, Thomas E Wellems, Jing Yuan, Cizhong Jiang, Qingfeng Zhang, 2022
A malaria parasite phospholipid flippase safeguards midgut traversal of ookinetes for mosquito transmission, Zhenke Yang, Yang Shi, Huiting Cui, Shuzhen Yang, Han Gao, Jing Yuan, 2021
Plasmodium transcription repressor AP2‐O3 regulates sex‐specific identity of gene expression in female gametocytes, Zhenkui Li, Huiting Cui, Jiepeng Guan, Cong Liu, Zhengang Yang, Jing Yuan, 2021
Generation of Plasmodium yoelii malaria parasite for conditional degradation of proteins, Chuanyuan Liu, Zhenke Yang, Mengya Cai, Yang Shi, Huiting Cui, Jing Yuan, 2021
A protein palmitoylation cascade regulates microtubule cytoskeleton integrity in Plasmodium, Xu Wang, Pengge Qian, Huiting Cui, Luming Yao, Jing Yuan, 2020
An intracellular membrane protein GEP1 regulates xanthurenic acid induced gametogenesis of malaria parasites, Yuanyuan Jiang, Jun Wei, Huiting Cui, Chuanyuan Liu, Yuan Zhi, ZhengZheng Jiang, Zhenkui Li, Shaoneng Li, Zhenke Yang, Xu Wang, Pengge Qian, Cui Zhang, Chuanqi Zhong, Xinzhuan Su, Jing Yuan, 2020
ISP1-anchored polarization of GCβ/CDC50A complex initiates malaria ookinete gliding motility, Han Gao, Zhenke Yang, Xu Wang, Pengge Qian, Renjie Hong, Xin Chen, Xinzhuan Su, Huiting Cui, Jing Yuan, 2018
Generation of Plasmodium yoelii malaria parasite carrying double fluorescence reporters in gametocytes, Cong Liu, Zhenkui Li, Yuanyuan Jiang, Huiting Cui, Jing Yuan, 2018
A Cas9 transgenic Plasmodium yoelii parasite for efficient gene editing, Pengge Qian, Xu Wang, Zhenke Yang, Zhenkui Li, Han Gao, XinZhuan Su, Huiting Cui, Jing Yuan, 2018
Systematic CRISPR-Cas9-Mediated Modifications of Plasmodium yoelii ApiAP2 Genes Reveal Functional Insights into Parasite Development, Cui Zhang, Zhenkui Li, Huiting Cui, Yuanyuan Jiang, Zhenke Yang, Xu Wang, Han Gao, Cong Liu, Shujia Zhang, XinZhuan Su, Jing Yuan, 2017
CRISPR/Cas9 mediated sequential editing of genes critical for ookinete motility in Plasmodium yoelii, Cui Zhang, Han Gao, Zhenke Yang, Yuanyuan Jiang, Zhenkui Li, Xu Wang, Bo Xiao, XinZhuan Su, Huiting Cui, Jing Yuan, 2017
Efficient Editing of Malaria Parasite Genome Using the CRISPR/Cas9 System, Cui Zhang, Bo Xiao, Yuanyuan Jiang, Yihua Zhao, Zhenkui Li, Han Gao, Yuan Ling, Jun Wei, Shaoneng Li, Mingke Lu, XinZhuan Su, Huiting Cui, Jing Yuan, 2014
Chemical genomic profiling for antimalarial therapies, response signatures and molecular targets, Jing Yuan, Ken Chih-Chien Cheng, Ronald Johnson, Ruili Huang, Sittiporn Pattaradilokrat, Anna Liu, Rajarshi Guha, David Fidock, James Inglese, Thomas E Wellems, Christopher Austin, Xinzhuan Su, 2011
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum, Jing Yuan, Ronald L Johnson, Ruili Huang, Jennifer Wichterman, Hongying Jiang, Karen Hayton, David A Fidock, Thomas E Wellems, James Inglese, Christopher P Austin, Xinzhuan Su, 2009

疟原虫按蚊感染寄生分子机制细胞机制 Crispr/Cas9 基因组编辑疟疾传播

钟涛 - 华东师范大学

邵洋洋 - 浙江大学

余勇 - 同济大学

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