Professor | 张四清 | 数字化转型顾问

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Name	张四清
Contact Information	siqing_zhang@yahoo.com
Language ability	英语, 中文
Province	福建

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Name

张四清

Contact Information

siqing_zhang@yahoo.com

Language ability

英语, 中文

Province

福建

University/Lab Affiliation and Title	厦门大学
Faculty	Life Sciences
Academic Background & Achievements	1985年 - 北京大学岩矿及地球化学专业，学士学位 1988年 - 北京大学地球化学专业，硕士学位 1995年 - 北京师范大学细胞生物学专业，博士学位
Work Experience	1997-2000年 - 以色列魏茨曼科学研究所 - 博士后 2000-2006年 - 美国哈佛大学医学院 - 博士后 2006年至今 - 厦门大学生命科学学院 - 教授

University/Lab Affiliation and Title

厦门大学

Faculty

Life Sciences

Academic Background & Achievements

1985年 - 北京大学岩矿及地球化学专业，学士学位
1988年 - 北京大学地球化学专业，硕士学位
1995年 - 北京师范大学细胞生物学专业，博士学位

Work Experience

1997-2000年 - 以色列魏茨曼科学研究所 - 博士后
2000-2006年 - 美国哈佛大学医学院 - 博士后
2006年至今 - 厦门大学生命科学学院 - 教授

Areas of Focus	肿瘤分子细胞生物学细胞凋亡和程序性细胞死亡
Publications	N-Myc-interacting protein (NMI) negatively regulates epithelial-mesenchymal transition by inhibiting the acetylation of NF-κB/p65., Hou J, Wang T, Xie Q, Deng W, Yang JY, Zhang SQ, Cai JC., 2016 Hsp90 modulates the stability of MLKL and is required for TNF-induced necroptosis., Zhao XM, Chen Z, Zhao JB, Zhang PP, Pu YF, Jiang SH, Hou JJ, Cui YM, Jia XL, Zhang SQ., 2016 NMI mediates transcription-independent ARF regulation in response to cellular stresses., Li Z, Hou J, Sun L, Wen T, Wang L, Zhao X, Xie Q, Zhang SQ., 2012 Shp2 regulates Src family kinase activity and Ras/Erk activation by controlling Csk recruitment., Si Qing Zhang, Wentian Yang, Maria I. Kontaridis, Trever G. Bivona, Gengyun Wen, Toshiyuki Araki, Jincai Luo, Julie A. Thompson, Burkhart L. Schraven, Mark R. Philips, & Benjamin G. Neel., 2004 Receptor-Specific Regulation of PI-3K Activation by the Protein-Tyrosine Phosphatase Shp2., Si Qing Zhang, William G. Tsiaras, Toshiyuki Araki, Gengyun Wen, Liliana Minichiello, Ruediger Klein, & Benjamin G. Neel., 2002 Recruitment of the IKK Signalosome to the p55 TNF Receptor: RIP and A20 Bind to NEMO (IKKg) upon Receptor Stimulation., Si Qing Zhang, Andrew Kovalenko, Giuseppina Cantarella & David Wallach., 2000 How are the regulators regulated? The search for mechanisms that impose specificity on induction of cell death and NF-kappaB activation by members of the TNF/NGF receptor family., Wallach D, Arumugam TU, Boldin MP, Cantarella G, Ganesh KA, Goltsev Y, Goncharov TM, Kovalenko AV, Rajput A, Varfolomeev EE, Zhang SQ., 2002 Shp2 regulates the relocalization of Gab1 in EGF signaling pathway., Si Qing Zhang & Benjamin G. Neel., 2001 8-Chloroadenosine induces various tumor cell death by apoptosis., Zhang SQ, Zheng DX, Liu SL, Zheng P, Min JM, Zhang LH., 1998 Z-ajoene induces tumor cell death by apoptosis., Zhang SQ, Zhao S, Min JM, Wang K, Liu SL, Zheng DX., 1998 Organosulfur compound z-ajoene from garlic extract induced apoptosis in various human tumor cell lines., Zhang, S. Q. & Zheng, D. X., 1996 Cell cycle regulation., Zhang, S. Q. & Wang, Y. C., 1996 Control of cell cycle., Zhang, S. Q. & Wang, Y. C., 1994

Areas of Focus

肿瘤分子细胞生物学
细胞凋亡和程序性细胞死亡

Publications

N-Myc-interacting protein (NMI) negatively regulates epithelial-mesenchymal transition by inhibiting the acetylation of NF-κB/p65., Hou J, Wang T, Xie Q, Deng W, Yang JY, Zhang SQ, Cai JC., 2016
Hsp90 modulates the stability of MLKL and is required for TNF-induced necroptosis., Zhao XM, Chen Z, Zhao JB, Zhang PP, Pu YF, Jiang SH, Hou JJ, Cui YM, Jia XL, Zhang SQ., 2016
NMI mediates transcription-independent ARF regulation in response to cellular stresses., Li Z, Hou J, Sun L, Wen T, Wang L, Zhao X, Xie Q, Zhang SQ., 2012
Shp2 regulates Src family kinase activity and Ras/Erk activation by controlling Csk recruitment., Si Qing Zhang, Wentian Yang, Maria I. Kontaridis, Trever G. Bivona, Gengyun Wen, Toshiyuki Araki, Jincai Luo, Julie A. Thompson, Burkhart L. Schraven, Mark R. Philips, & Benjamin G. Neel., 2004
Receptor-Specific Regulation of PI-3K Activation by the Protein-Tyrosine Phosphatase Shp2., Si Qing Zhang, William G. Tsiaras, Toshiyuki Araki, Gengyun Wen, Liliana Minichiello, Ruediger Klein, & Benjamin G. Neel., 2002
Recruitment of the IKK Signalosome to the p55 TNF Receptor: RIP and A20 Bind to NEMO (IKKg) upon Receptor Stimulation., Si Qing Zhang, Andrew Kovalenko, Giuseppina Cantarella & David Wallach., 2000
How are the regulators regulated? The search for mechanisms that impose specificity on induction of cell death and NF-kappaB activation by members of the TNF/NGF receptor family., Wallach D, Arumugam TU, Boldin MP, Cantarella G, Ganesh KA, Goltsev Y, Goncharov TM, Kovalenko AV, Rajput A, Varfolomeev EE, Zhang SQ., 2002
Shp2 regulates the relocalization of Gab1 in EGF signaling pathway., Si Qing Zhang & Benjamin G. Neel., 2001
8-Chloroadenosine induces various tumor cell death by apoptosis., Zhang SQ, Zheng DX, Liu SL, Zheng P, Min JM, Zhang LH., 1998
Z-ajoene induces tumor cell death by apoptosis., Zhang SQ, Zhao S, Min JM, Wang K, Liu SL, Zheng DX., 1998
Organosulfur compound z-ajoene from garlic extract induced apoptosis in various human tumor cell lines., Zhang, S. Q. & Zheng, D. X., 1996
Cell cycle regulation., Zhang, S. Q. & Wang, Y. C., 1996
Control of cell cycle., Zhang, S. Q. & Wang, Y. C., 1994

细胞周期调控癌基因抑癌基因细胞凋亡程序性细胞死亡信号传导 Bcl-2家族蛋白 Dna损伤癌症治疗 Nf-Κb

徐冬一 - 北京大学

林安宁 - 中国科学院大学

Area of Focus
信号转导 | 基因调控 | Nf-Κb | Miz1 | Tnf | Il-17 | 炎症 | 癌症 | 细胞凋亡 | Ikk

孙钦秒 - 中国科学院大学

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