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毕文健
Basic Medical Sciences
北京大学
北京
Language: 中文, 英语
遗传学
环境互动
生存数据
多类表型数据
分析算法
英国生物样本库
生物医学数据
高通量测序
健康医疗信息化
大数据
Areas of Focus
- 统计遗传学
- 生物统计与系统生物学
- 系统辨识与控制算法
Work Experience
- 2015-2018 - 圣裘德儿童研究医院, 博士后研究员
- 2018-2021 - 密歇根大学, 博士后研究员
- 2021-至今 - 北京大学, 课题组长
Academic Background & Achievements
- 2010 - 学士: 四川大学数学学院
- 2015 - 博士: 中国科学院数学与系统科学研究院
- 国家级青年高层次人才计划入选者
Publications
- Efficient mixed model approach for large-scale genome-wide association studies of ordinal categorical phenotypes, 毕文健等, 2021
- A fast and accurate method for genome-wide time-to-event data analysis and its application to UK-Biobank, 毕文健等, 2020
- A fast and accurate method for genome-wide scale phenome-wide G×E analysis and its application to UK Biobank, 毕文健等, 2019
- STEPS: an efficient prospective likelihood approach to genetic association analyses of secondary traits in extreme phenotype sequencing, 毕文健等, 2020
- A robust and powerful set-valued approach to rare variant association analyses of secondary traits in case-control sequencing studies, 毕文健等, 2017
- Extreme-value sampling design is cost-benefit only with valid statistical approach for exposure-secondary outcome association analyses, 毕文健等, 2020
- A system identification approach to identifying genetic variants in sequencing studies for a binary phenotype, 毕文健等, 2014
- SVSI: A fast and powerful set-valued system identification approach to identifying rare variants in sequencing studies for ordered categorical traits, 毕文健等, 2015
- Iterative parameter estimate with batched binary-valued observations: convergence with an exponential rate, 毕文健等, 2014
- Set-valued system identification methods in retrospective cohort study and applications to GWAS, 毕文健等, 2017
- Protein-interaction-network-based analysis for genome-wide association analysis of schizophrenia in Han Chinese population, 毕文健等, 2014
- A hypothesis-driven pathway analysis reveals Myelin-related pathways that contribute to the risk of schizophrenia and bipolar disorder, 毕文健等, 2014
- Scalable generalized linear mixed model for region-based association tests in large biobanks and cohorts, 毕文健等, 2020
- UK-Biobank whole exome sequence binary phenome analysis with robust region-based rare variant test, 毕文健等, 2020
- Consensus protocol for multiagent systems with undirected topologies and binary-valued communications, 毕文健等, 2019
- Iterative parameter estimate with batched binary-valued observations, 毕文健等, 2016
