Professor | 姬燕晓 | 数字化转型顾问

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Name

姬燕晓

Contact Information

jiyanxiao@whu.edu.cn

Language ability

中文, 英语

Province

湖北省

University/Lab Affiliation and Title	武汉大学
Faculty	Basic Medical Sciences
Academic Background & Achievements	2005-2009 生物工程本科：成都理工大学 2009-2015 遗传学博士：武汉大学
Work Experience	2015-2017 博士后，武汉大学基础医学院 2017-2021 助理研究员，武汉大学中南医院 2021-至今特聘研究员，武汉大学基础医学院

University/Lab Affiliation and Title

武汉大学

Faculty

Basic Medical Sciences

Academic Background & Achievements

Work Experience

Areas of Focus	蛋白质翻译后修饰与代谢性疾病机制基于靶点的抗体、小分子药物研发
Publications	A kinome screen reveals that Nemo-like Kinase is a key upstream regulator of hepatic gluconeogenesis, 姬燕晓等, 2021 Hepatic Regulator of G protein Signaling 5 Ameliorates NAFLD by Suppressing TAK1-JNK/p38 Signaling, 王佳等, 2020 Milk Fat Globule–Epidermal Growth Factor–Factor 8 Improves Hepatic Steatosis and Inflammation, 张立等, 2020 Metformin Is Associated with Higher Incidence of Acidosis, but Not Mortality, in Individuals with COVID-19 and Pre-existing Type 2 Diabetes, 程晓等, 2020 F-box/WD Repeat-Containing Protein 5 Mediates the Ubiquitination of Apoptosis Signal-Regulating Kinase 1 and Exacerbates Nonalcoholic Steatohepatitis in Mice, 白丽等, 2019 Hepatic IRF2BP2 Mitigates Nonalcoholic Fatty Liver Disease by Directly Repressing the Transcription of ATF3, 方俊等, 2019 The deubiquitinating enzyme cylindromatosis mitigates nonalcoholic steatohepatitis, 姬燕晓等, 2018 Targeting CASP8 and FADD-like apoptosis regulator ameliorates nonalcoholic steatohepatitis in mice and nonhuman primates, 王培兴等, 2017 The ubiquitin E3 ligase TRAF6 exacerbates pathological cardiac hypertrophy via TAK1-dependent signalling, 姬燕晓等, 2016 Suppressor of IKKvarepsilon is an essential negative regulator of pathological cardiac hypertrophy, 邓康强等, 2016

Areas of Focus

蛋白质翻译后修饰与代谢性疾病机制
基于靶点的抗体、小分子药物研发

Publications

A kinome screen reveals that Nemo-like Kinase is a key upstream regulator of hepatic gluconeogenesis, 姬燕晓等, 2021
Hepatic Regulator of G protein Signaling 5 Ameliorates NAFLD by Suppressing TAK1-JNK/p38 Signaling, 王佳等, 2020
Milk Fat Globule–Epidermal Growth Factor–Factor 8 Improves Hepatic Steatosis and Inflammation, 张立等, 2020
Metformin Is Associated with Higher Incidence of Acidosis, but Not Mortality, in Individuals with COVID-19 and Pre-existing Type 2 Diabetes, 程晓等, 2020
F-box/WD Repeat-Containing Protein 5 Mediates the Ubiquitination of Apoptosis Signal-Regulating Kinase 1 and Exacerbates Nonalcoholic Steatohepatitis in Mice, 白丽等, 2019
Hepatic IRF2BP2 Mitigates Nonalcoholic Fatty Liver Disease by Directly Repressing the Transcription of ATF3, 方俊等, 2019
The deubiquitinating enzyme cylindromatosis mitigates nonalcoholic steatohepatitis, 姬燕晓等, 2018
Targeting CASP8 and FADD-like apoptosis regulator ameliorates nonalcoholic steatohepatitis in mice and nonhuman primates, 王培兴等, 2017
The ubiquitin E3 ligase TRAF6 exacerbates pathological cardiac hypertrophy via TAK1-dependent signalling, 姬燕晓等, 2016
Suppressor of IKKvarepsilon is an essential negative regulator of pathological cardiac hypertrophy, 邓康强等, 2016

翻译后代谢性疾病机制蛋白质修饰药物开发抗体小分子基于靶点研究治疗

王宪 - 北京大学

孔炜 - 北京大学

Area of Focus
血管 | 微环境 | 心血管 | 疾病 | 病理生理学 | 研究 | 生物学 | 临床 | 治疗 | 预防

魏雅槟 - 北京大学

Area of Focus
抑郁症 | 躁狂症 | 治疗 | 机制 | 儿童 | 孤独症 | 神经发展 | 药物基因组学 | 干细胞 | 器官

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