Professor | 朱作言 | 数字化转型顾问

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Name	朱作言
Contact Information	zyzhu (AT) pku.edu.cn
Language ability	中文, 英语
Province	北京

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Name

朱作言

Contact Information

zyzhu (AT) pku.edu.cn

Language ability

中文, 英语

Province

北京

University/Lab Affiliation and Title	北京大学
Faculty	Life Sciences
Academic Background & Achievements	1978 - 1980: 理学硕士, 细胞及发育生物学专业, 中国科学院研究生院 1959 - 1965: 理学学士, 人体及动物生理专业, 北京大学生物系
Work Experience	2000 - 至今: 教授, 北京大学生命科学学院遗传与发育中心主任 2000 - 2007: 副主任, 国家自然科学基金委 1991 - 1994: 高级讲师, 英国阿伯丁大学 1989 - 至今: 研究员, 中国科学院水生生物研究所所长 1988 - 1991: 教授研究员, 美国马里兰大学海洋生物技术中心 1984 - 1984: Hill-访问教授, 美国明尼苏达大学 1982 - 1983: 访问学者, 美国波士顿遗传研究所 1981 - 1982: 访问学者, 英国伦敦帝国肿瘤研究所
Awards	1998: 当选为第三世界科学院院士 1997: 当选为中国科学院院士

University/Lab Affiliation and Title

北京大学

Faculty

Life Sciences

Academic Background & Achievements

1978 - 1980: 理学硕士, 细胞及发育生物学专业, 中国科学院研究生院
1959 - 1965: 理学学士, 人体及动物生理专业, 北京大学生物系

Work Experience

2000 - 至今: 教授, 北京大学生命科学学院遗传与发育中心主任
2000 - 2007: 副主任, 国家自然科学基金委
1991 - 1994: 高级讲师, 英国阿伯丁大学
1989 - 至今: 研究员, 中国科学院水生生物研究所所长
1988 - 1991: 教授研究员, 美国马里兰大学海洋生物技术中心
1984 - 1984: Hill-访问教授, 美国明尼苏达大学
1982 - 1983: 访问学者, 美国波士顿遗传研究所
1981 - 1982: 访问学者, 英国伦敦帝国肿瘤研究所

Awards

1998: 当选为第三世界科学院院士
1997: 当选为中国科学院院士

Areas of Focus	以斑马鱼、果蝇、线虫等模式动物为材料，探索动物发育调控的分子机制以及相关的疾病模型的研究以水生脊椎动物为材料，通过显微操作技术，探索发育过程中的核质关系以及胞质因子对发育和形态建成的影响
Publications	Heritable/conditional genome editing in C. elegans using a CRISPR-Cas9 feeding system, Pengpeng Liu, Lijiang Long, Kai Xiong, Bo Yu, Nannan Chang, Jing-Wei Xiong, Zuoyan Zhu, Dong Liu, 2014 The Drosophila ortholog of breast cancer metastasis suppressor gene, dBrms1, is critical for developmental timing through regulating ecdysone signaling, Shilin Song, Yuan Yuan, Jinfeng Lu, Qi Li, Zuoyan Zhu, Qichang Fan, Youfang Xue, Zhi-Chun Lai, Wenxia Zhang, 2013 mir-35 is involved in intestine cell G1/S transition and germ cell proliferation in C. elegans, Min Liu, Pengpeng Liu, Li Zhang, Qingchun Cai, Ge Gao, Wenxia Zhang, Zuoyan Zhu, Dong Liu, Qichang Fan, 2011 Detection of intergenic non-coding RNAs expressed in the main developmental stages in Drosophila melanogaster, Zheng Li, Min Liu, Li Zhang, Wenxia Zhang, Ge Gao, Zuoyan Zhu, Liping Wei, Qichang Fan, Manyuan Long, 2009 The Function of a Spindle Checkpoint Gene bub-1 in C. elegans Development, Xiangming Wang, Min Liu, Weida Li, Christopher D. Suh, Zuoyan Zhu, Yishi Jin, Qichang Fan, 2009 Visualization of monoaminergic neurons and neurotoxicity of MPTP in live transgenic zebrafish, Wen, Lu, Wei, Wei, Wenchao Gu, Peng Huang, Xi Ren, Zheng Zhang, Zuoyan Zhu, Shuo Lin, Bo Zhang, 2008 Efficient genome-wide mutagenesis of zebrafish genes by retroviral insertions, Dongmei Wang, Li-En Jao, Naizhong Zheng, Kyle Dolan, Jessica Ivey, Seth Zonies, Xiaolin Wu, Kangmai Wu, Hongbo Yang, Qingchao Meng, Zuoyan Zhu, Bo Zhang, Shuo Lin, Shawn M. Burgess, 2007 Vertebrate MAX-1 is required for vascular patterning in zebrafish, Hanbing Zhong, Xinrong Wu, Haigen Huang, Qichang Fan, Zuoyan Zhu, Shuo Lin, 2006 Screening for Genes Essential for Mouse Embryonic Stem Cell Self-Renewal Using a Substractive RNA Interference Library, Jun-zheng Zhang, Wei Gao, Hong-Bo Yang, Bo Zhang, Zuo-yan Zhu, You-fang Xue, 2006 Cytoplasmic impact on cross-genus cloned fish derived from transgenic common carp (Cyprinus carpio) nuclei and goldfish (Carassius auratus) enucleated eggs, Sun YH, Chen SP, Wang YP, Hu W, Zhu ZY, 2005 Primary-structural and evolutionary analyses of the growth-hormone gene from grass carp (Ctenopharyngodon idellus), Zhu ZY, He L, Chen TT, 1992 Novel gene transfer into the fertilized eggs of goldfish (Carassius auratus L.1758), Zhu ZY, Li G, He L, Chen S, 1985

Areas of Focus

以斑马鱼、果蝇、线虫等模式动物为材料，探索动物发育调控的分子机制以及相关的疾病模型的研究
以水生脊椎动物为材料，通过显微操作技术，探索发育过程中的核质关系以及胞质因子对发育和形态建成的影响

Publications

Heritable/conditional genome editing in C. elegans using a CRISPR-Cas9 feeding system, Pengpeng Liu, Lijiang Long, Kai Xiong, Bo Yu, Nannan Chang, Jing-Wei Xiong, Zuoyan Zhu, Dong Liu, 2014
The Drosophila ortholog of breast cancer metastasis suppressor gene, dBrms1, is critical for developmental timing through regulating ecdysone signaling, Shilin Song, Yuan Yuan, Jinfeng Lu, Qi Li, Zuoyan Zhu, Qichang Fan, Youfang Xue, Zhi-Chun Lai, Wenxia Zhang, 2013
mir-35 is involved in intestine cell G1/S transition and germ cell proliferation in C. elegans, Min Liu, Pengpeng Liu, Li Zhang, Qingchun Cai, Ge Gao, Wenxia Zhang, Zuoyan Zhu, Dong Liu, Qichang Fan, 2011
Detection of intergenic non-coding RNAs expressed in the main developmental stages in Drosophila melanogaster, Zheng Li, Min Liu, Li Zhang, Wenxia Zhang, Ge Gao, Zuoyan Zhu, Liping Wei, Qichang Fan, Manyuan Long, 2009
The Function of a Spindle Checkpoint Gene bub-1 in C. elegans Development, Xiangming Wang, Min Liu, Weida Li, Christopher D. Suh, Zuoyan Zhu, Yishi Jin, Qichang Fan, 2009
Visualization of monoaminergic neurons and neurotoxicity of MPTP in live transgenic zebrafish, Wen, Lu, Wei, Wei, Wenchao Gu, Peng Huang, Xi Ren, Zheng Zhang, Zuoyan Zhu, Shuo Lin, Bo Zhang, 2008
Efficient genome-wide mutagenesis of zebrafish genes by retroviral insertions, Dongmei Wang, Li-En Jao, Naizhong Zheng, Kyle Dolan, Jessica Ivey, Seth Zonies, Xiaolin Wu, Kangmai Wu, Hongbo Yang, Qingchao Meng, Zuoyan Zhu, Bo Zhang, Shuo Lin, Shawn M. Burgess, 2007
Vertebrate MAX-1 is required for vascular patterning in zebrafish, Hanbing Zhong, Xinrong Wu, Haigen Huang, Qichang Fan, Zuoyan Zhu, Shuo Lin, 2006
Screening for Genes Essential for Mouse Embryonic Stem Cell Self-Renewal Using a Substractive RNA Interference Library, Jun-zheng Zhang, Wei Gao, Hong-Bo Yang, Bo Zhang, Zuo-yan Zhu, You-fang Xue, 2006
Cytoplasmic impact on cross-genus cloned fish derived from transgenic common carp (Cyprinus carpio) nuclei and goldfish (Carassius auratus) enucleated eggs, Sun YH, Chen SP, Wang YP, Hu W, Zhu ZY, 2005
Primary-structural and evolutionary analyses of the growth-hormone gene from grass carp (Ctenopharyngodon idellus), Zhu ZY, He L, Chen TT, 1992
Novel gene transfer into the fertilized eggs of goldfish (Carassius auratus L.1758), Zhu ZY, Li G, He L, Chen S, 1985

斑马鱼果蝇线虫分子机制发育调控疾病模型显微操作水生脊椎动物胞质因子形态建成

郑雅 - 上海师范大学

梁婉琪 - 上海交通大学

钟涛 - 华东师范大学

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