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谢敬
Life Science
同济大学
上海
Language: 中文, 英语
非对称分裂
干细胞
表观遗传学
细胞命运
细胞分裂
基因表达
组织发育
疾病机制
再生医学
分子生物学
Areas of Focus
- 干细胞的非对称细胞分裂
- 干细胞命运决定中的表观遗传机制
Work Experience
- 2012-2017年 - 约翰霍普金斯大学：博士后研究
- 2017年至今 - 同济大学生命科学与技术学院：研究员和博士生导师
Academic Background & Achievements
- 2010年 - 博士学位：中国科学院上海生物化学与细胞生物学研究所
- 在包括Cell、Science和Trends in Cell Biology在内的国际期刊上发表文章
- 持有多项美国技术专利
Publications
- Breaking Symmetry—Asymmetry Histone Inheritance in Stem Cells, 谢敬, Wooten M., Tran V., 陈X., 2017
- Histone H3 Threonine 3 Phosphorylation Regulates Asymmetric Histone Inheritance in the in Drosophila Male Germline, 谢敬, Wooten M., Tran V., 陈BZ., Pozmanter C., Simbolon C., Betzig E., 陈X., 2015
- A Novel Function of Acetylcholinesterase: AChE Plays as a DNase that Degrades DNA during Apoptosis, 杜AY., 谢敬, 郭KJ., 万YH., 杨雷, 牛X., 吴J., 董XQ., 张XJ., 2015
- Asymmetric Division of Drosophila Male Germline Stem Cell Shows Asymmetric Histone Distribution, Tran V., Lim C., 谢敬, 陈X., 2012
- Acetylcholinesterase Blocks Cleavage of APP by γ-secretase in 293 Cells and Mouse Brain, 牛X., 张XJ., 谢敬, 张XJ., 2012
- Induction of a 55 kDa Acetylcholinesterase (AChE) Protein during Apoptosis and its Negative Regulation by the Akt Pathway, 谢敬, 江H., 万YH., 杜AY., 郭KJ., 刘T., 叶WY., 牛X., 吴J., 董XQ., 张XJ., 2011
- AChE Deficiency or Inhibition Decreases Apoptosis and p53 Expression and Protects Renal Function after Ischemia/Reperfusion, 叶WY., 宫XW., 谢敬, 吴J., 张XJ., 欧阳Q., 石YF., 张XJ., 2010
- Acetylcholinesterase in Intestinal Cell Differentiation involves G2/M Cell Cycle Arrest, 项AC., 谢敬, 张XJ., 2008
- Mitochondria and Calpains Mediate Caspase-Dependent Apoptosis Induced by Doxycycline in HeLa Cells, 吴JC., 刘TJ., 谢敬, 辛F., 郭LH., 2006
