Professor | 姬燕晓 | 数字化转型顾问

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Name

姬燕晓

Contact Information

jiyanxiao@whu.edu.cn

Language ability

中文, 英语

Province

湖北省

University/Lab Affiliation and Title	武汉大学
Faculty	Medical School
Academic Background & Achievements	2005.9~2009.6 成都理工大学生物工程本科 2009.9~2015.7 武汉大学遗传学博士
Work Experience	2015.8~2017.6 武汉大学基础医学院博士后 2017.7~2021.7 武汉大学中南医院助理研究员 2021.8~今武汉大学基础医学院特聘研究员

University/Lab Affiliation and Title

武汉大学

Faculty

Medical School

Academic Background & Achievements

Work Experience

Areas of Focus	翻译后修饰与代谢性疾病机制基于靶点的抗体、小分子药物研发
Publications	A kinome screen reveals that Nemo-like Kinase is a key upstream regulator of hepatic gluconeogenesis, 姬燕晓等, 2021 Hepatic Regulator of G protein Signaling 5 Ameliorates NAFLD by Suppressing TAK1-JNK/p38 Signaling, 王佳等, 2020 Milk Fat Globule–Epidermal Growth Factor–Factor 8 Improves Hepatic Steatosis and Inflammation, 张丽等, 2020 Metformin Is Associated with Higher Incidence of Acidosis, but Not Mortality, in Individuals with COVID-19 and Pre-existing Type 2 Diabetes, 程晓等, 2020 F-box/WD Repeat-Containing Protein 5 Mediates the Ubiquitination of Apoptosis Signal-Regulating Kinase 1 and Exacerbates Nonalcoholic Steatohepatitis in Mice, 白丽等, 2019 Hepatic IRF2BP2 Mitigates Nonalcoholic Fatty Liver Disease by Directly Repressing the Transcription of ATF3, 方佳等, 2019 The deubiquitinating enzyme cylindromatosis mitigates nonalcoholic steatohepatitis, 姬燕晓等, 2018 Targeting CASP8 and FADD-like apoptosis regulator ameliorates nonalcoholic steatohepatitis in mice and nonhuman primates, 王培霞等, 2017 The ubiquitin E3 ligase TRAF6 exacerbates pathological cardiac hypertrophy via TAK1-dependent signalling, 姬燕晓等, 2016 Suppressor of IKKvarepsilon is an essential negative regulator of pathological cardiac hypertrophy, 邓康强等, 2016

Areas of Focus

翻译后修饰与代谢性疾病机制
基于靶点的抗体、小分子药物研发

Publications

A kinome screen reveals that Nemo-like Kinase is a key upstream regulator of hepatic gluconeogenesis, 姬燕晓等, 2021
Hepatic Regulator of G protein Signaling 5 Ameliorates NAFLD by Suppressing TAK1-JNK/p38 Signaling, 王佳等, 2020
Milk Fat Globule–Epidermal Growth Factor–Factor 8 Improves Hepatic Steatosis and Inflammation, 张丽等, 2020
Metformin Is Associated with Higher Incidence of Acidosis, but Not Mortality, in Individuals with COVID-19 and Pre-existing Type 2 Diabetes, 程晓等, 2020
F-box/WD Repeat-Containing Protein 5 Mediates the Ubiquitination of Apoptosis Signal-Regulating Kinase 1 and Exacerbates Nonalcoholic Steatohepatitis in Mice, 白丽等, 2019
Hepatic IRF2BP2 Mitigates Nonalcoholic Fatty Liver Disease by Directly Repressing the Transcription of ATF3, 方佳等, 2019
The deubiquitinating enzyme cylindromatosis mitigates nonalcoholic steatohepatitis, 姬燕晓等, 2018
Targeting CASP8 and FADD-like apoptosis regulator ameliorates nonalcoholic steatohepatitis in mice and nonhuman primates, 王培霞等, 2017
The ubiquitin E3 ligase TRAF6 exacerbates pathological cardiac hypertrophy via TAK1-dependent signalling, 姬燕晓等, 2016
Suppressor of IKKvarepsilon is an essential negative regulator of pathological cardiac hypertrophy, 邓康强等, 2016

翻译后修饰代谢性疾病机制蛋白质修饰药物开发抗体小分子基于靶点治疗学生物化学

陈浩 - 南方科技大学

Area of Focus
表观遗传学 | 疾病 | 机制 | 鉴定 | 修饰 | 功能研究 | 癌症 | 代谢性疾病 | 糖尿病 | 高血压

许鹏飞 - 武汉大学

陈静 - 中国科学院大学

Area of Focus
代谢性疾病 | 药理学 | 药物开发 | 肝病 | 糖尿病 | 肥胖 | 非酒精性脂肪肝病 | 纤维化 | 微小Rna | 脂质代谢

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