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许杰
Medical School
武汉大学
湖北
Language: 中文, 英语
代谢
神经调控
瘦素抵抗
肥胖
厌食症
摄食信号
恶病质
中枢调节
血糖
神经生物学
Areas of Focus
- 代谢的神经调控
- 瘦素抵抗的分子机制研究
- 肥胖、厌食症中摄食信号的功能研究
- 恶病质的中枢调节机制研究
- 血糖的中枢调节研究
Work Experience
- 2015-08至2021-02，塔夫茨大学，神经生物学系，博士后
- 2021-03至2023-09，哈佛医学院，波士顿儿童医院，内分泌系，讲师
- 2023-10至今，武汉大学，泰康医学院（基础医学院），教授
Academic Background & Achievements
- 2006-09至2010-06，南京大学，生命科学院，生物，学士
- 2010-09至2015-06，南京大学，生命科学院，生物化学，博士
- 2013-07至2015-06，哈佛医学院，BIDMC，内分泌系，神经和代谢，博士（联合培养）
Publications
- Genetic identification of leptin neural circuits in energy and glucose homeostasis, Jie Xu, Bartolome CL, Low CS, Yi X, Chien CH, Wang P, Kong D, 2018
- Synaptosomes secrete and uptake functionally active microRNAs via exocytosis and endocytosis pathways, Jie Xu, Chen Q, Zen K, Zhang C, Zhang Q, 2013
- Small RNA existed in commercial reverse transcriptase: primary evidence of functional small RNAs, Jie Xu, Xi Chen, Donghai Li, Qun Chen, Zhen Zhou, Dongxia Hou, Jin Wang, Qipeng Zhang, Ke Zen, Chen-Yu Zhang, 2014
- MicroRNA-23a/b and microRNA-27a/b suppress Apaf-1 protein and alleviate hypoxia-induced neuronal apoptosis, Q Chen, Jie Xu, L Li, H Li, S Mao, F Zhang, K Zen, CY Zhang, Q Zhang, 2014
- Selective secretion of microRNA in CNS system, Zhang Q, Jie Xu, Chen Q, Chen X, Zen K, Zhang CY, 2014
- Identification and characterization of the MicroRNA profile in aging rats with erectile dysfunction, Pan F, Jie Xu, Zhang Q, Qiu X, Yu W, Jiadong Xia, Taowei Chen, Lianjun Pan, Yun Chen, Yutian Dai, 2014
- SIDT1dependent absorption in the stomach mediates host uptake of dietary and orally administered microRNAs, Chen Q, Zhang F, Dong L, Wu H, Jie Xu, Li H, Wang J, Zhou Z, Liu C, Wang Y, Liu Y, Lu L, Wang C, Liu M, Chen X, Wang C, Zhang C, Li D, Zen K, Wang F, Zhang Q, Zhang CY, 2020
- A rapidly acting glutamatergic ARC→PVH satiety circuit postsynaptically regulated by αMSH, Henning Fenselau, John N Campbell, Anne MJ Verstegen, Joseph C Madara, Jie Xu, Bhavik P Shah, Jon M Resch, Zongfang Yang, Yael Mandelblat-Cerf, Yoav Livneh, Bradford B Lowell, 2017
- PNOCARC Neurons Promote Hyperphagia and Obesity upon High-Fat-Diet Feeding, Jais A, Paeger L, Sotelo-Hitschfeld T, Bremser S, Prinzensteiner M, Klemm P, Mykytiuk V, Widdershooven PJM, Vesting AJ, Grzelka K, Minère M, Cremer AL, Jie Xu, Korotkova T, Lowell BB, Zeilhofer HU, Backes H, Fenselau H, Wunderlich FT, Kloppenburg P, Brüning JC, 2020
- Anterior thalamic dysfunction underlies cognitive deficits in a subset of neuropsychiatric disease models, Dheeraj S Roy, Ying Zhang, Tomomi Aida, Soonwook Choi, Qian Chen, Yuanyuan Hou, Nicholas E Lea, Keith M Skaggs, Juliana C Quay, Min Liew, Vinh Le, Carter Jones, Jie Xu, Dong Kong, Heather A Sullivan, Arpiar Saunders, Steven A McCarroll, Ian R Wickersham, Guoping Feng, 2021
