Professor | 鲁丽 | 数字化转型顾问

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Name	鲁丽
Contact Information	luliwhu@whu.edu.cn
Language ability	中文, 英语
Province	湖北省

Upload Avatar (500 x 500)

Name

鲁丽

Contact Information

luliwhu@whu.edu.cn

Language ability

中文, 英语

Province

湖北省

University/Lab Affiliation and Title	武汉大学
Faculty	Medical School
Academic Background & Achievements	2003.09 - 2007.07 华中农业大学，生命科学与技术学院，生物科学理科基地,本科 2006.09 - 2012.12 华中农业大学，生命科学与技术学院，遗传学，博士
Work Experience	2014.04 - 2017.12 美国威斯康星大学麦迪逊分校，遗传学系，博士后 2017.12 - 2018.12 美国威斯康星大学麦迪逊分校，医学研究院，助理研究员 2019.09 - 至今武汉大学药学院，特聘研究员
Awards	2023湖北省青年拔尖人才 2023湖北省楚天学子 2022国家重点研发计划“合成生物学”重点专项子课题 2022湖北省自然科学基金青年基金 2021国家自然科学基金青年基金

University/Lab Affiliation and Title

武汉大学

Faculty

Medical School

Academic Background & Achievements

2003.09 - 2007.07 华中农业大学，生命科学与技术学院，生物科学理科基地,本科
2006.09 - 2012.12 华中农业大学，生命科学与技术学院，遗传学，博士

Work Experience

2014.04 - 2017.12 美国威斯康星大学麦迪逊分校，遗传学系，博士后
2017.12 - 2018.12 美国威斯康星大学麦迪逊分校，医学研究院，助理研究员
2019.09 - 至今武汉大学药学院，特聘研究员

Awards

2023湖北省青年拔尖人才
2023湖北省楚天学子
2022国家重点研发计划“合成生物学”重点专项子课题
2022湖北省自然科学基金青年基金
2021国家自然科学基金青年基金

Areas of Focus	植物天然产物的分子合成途径解析植物合成生物学植物来源生物农药植物香精香料
Publications	Identification and Characterization of Glycosyltransferases Involved in the Biosynthesis of Neodiosmin, Xiaosa Chang, Xueting Fang, Yan Yao, Zhenni Xu, Chaoyan Wu, Li Lu, 2024 Integrative multi-omics profiling of passion fruit reveals the genetic basis for fruit color and aroma, Yu-Yu Zheng, Lin-Hua Chen, Bing-Liang Fan, Zhenni Xu, Qiuxia Wang, Bo-Yuan Zhao, Min Gao, Min-Hui Yuan, Muhammad Tahirul Qamar, Yuanyuan Jiang, Liu Yang, Lingqiang Wang, Weihui Li, Wenguo Cai, Chongjian Ma, Li Lu, Jia-Ming Song, Ling-Ling Chen, 2024 Complete pathway elucidation and heterologous reconstitution of (+)-nootkatone biosynthesis from Alpinia oxyphylla, Xiaomin Deng, Ziling Ye, Jingyu Duan, Fangfang Chen, Yao Zhi, Man Huang, Minjian Huang, Weijia Cheng, Yujie Dou, Zhaolin Kuang, Yanglei Huang, Guangkai Bian, Zixin Deng, Tiangang Liu, Li Lu, 2024 Functional characterization and structural basis of a reversible glycosyltransferase involves in plant chemical defense, Weijia Cheng, Xueting Fang, Zhifeng Guan, Yan Yao, Zhenni Xu, Yunya Bi, Kexin Ren, Jiwen Li, Fangfang Chen, Xiangsong Chen, Weihua Ma, Zhaohui Chu, Zixin Deng, Zhengyu Zhang, Li Lu, 2023 Characterization of benzylisoquinoline alkaloid methyltransferases in Liriodendron chinense provides insights into the phylogenic basis of angiosperm alkaloid diversity, Weijia Cheng, Yan Yao, Qiuxia Wang, Xiaosa Chang, Zhuolin Shi, Xueting Fang, Fangfang Chen, Shixin Chen, Yonghong Zhang, Fan Zhang, Dongqing Zhu, Zixin Deng, Li Lu, 2022 EGR1 Addiction in Diffuse Large B-cell Lymphoma, Kimpara S, Lu L, Hoang NM, Zhu F, Bates PD, Daenthanasanmak A, Zhang S, Yang DT, Kelm A, Liu Y, Li Y, Rosiejka A, Kondapelli A, Bebel S, Chen M, Waldmann TA, Capitini CM, Rui L, 2021 Inhibition of the STAT3 target SGK1 sensitizes diffuse large B cell lymphoma cells to AKT inhibitors, Li Lu, Fen Zhu, Yangguang Li, Shuichi Kimpara, Nguyet Minh Hoang, Sheida Pourdashti, Lixin Rui, 2019 The plant-specific histone residue Phe41 is important for genome-wide H3.1 distribution, Li Lu, Xiangsong Chen, Shuiming Qian, Xuehua Zhong, 2018 Gene regulation and suppression of type I interferon signaling by STAT3 in diffuse large B cell lymphoma, Li Lu, Fen Zhu, Meili Zhang, Yangguang Li, Amanda C. Drennan, Shuichi Kimpara, Ian Rumball, Christopher Selzer, Hunter Cameron, Ashley Kellicut, Amanda Kelm, Fangyu Wang, Thomas A Waldmann, Lixin Rui, 2018 Systematic identification of Ctr9 regulome in ERα-positive breast cancer, Zeng H, Lu L, Chan NT, Horswill M, Ahlquist P, Zhong X, Xu W, 2016 High-resolution mapping of H4K16 and H3K23 acetylation reveals conserved and unique distribution patterns in Arabidopsis and rice, Li Lu, Xiangsong Chen, Dean Sanders, Shuiming Qian, Xuehua Zhong, 2015 CRISPR-P: A web tool for synthetic single-guide RNA design of CRISPR-system in plants, Yang Lei, Li Lu, Hai-Yang Liu, Sen Li, Feng Xing, Ling-Ling Chen, 2014 Natural variation and artificial selection in four genes determine grain shape in rice, Li Lu, Di Shao, Xianjing Qiu, Liang Sun, Xiangchun Zhou, Wenhao Yan, Lin Yang, Yuqing

Areas of Focus

植物天然产物的分子合成途径解析
植物合成生物学
植物来源生物农药
植物香精香料

Publications

Identification and Characterization of Glycosyltransferases Involved in the Biosynthesis of Neodiosmin, Xiaosa Chang, Xueting Fang, Yan Yao, Zhenni Xu, Chaoyan Wu, Li Lu, 2024
Integrative multi-omics profiling of passion fruit reveals the genetic basis for fruit color and aroma, Yu-Yu Zheng, Lin-Hua Chen, Bing-Liang Fan, Zhenni Xu, Qiuxia Wang, Bo-Yuan Zhao, Min Gao, Min-Hui Yuan, Muhammad Tahirul Qamar, Yuanyuan Jiang, Liu Yang, Lingqiang Wang, Weihui Li, Wenguo Cai, Chongjian Ma, Li Lu, Jia-Ming Song, Ling-Ling Chen, 2024
Complete pathway elucidation and heterologous reconstitution of (+)-nootkatone biosynthesis from Alpinia oxyphylla, Xiaomin Deng, Ziling Ye, Jingyu Duan, Fangfang Chen, Yao Zhi, Man Huang, Minjian Huang, Weijia Cheng, Yujie Dou, Zhaolin Kuang, Yanglei Huang, Guangkai Bian, Zixin Deng, Tiangang Liu, Li Lu, 2024
Functional characterization and structural basis of a reversible glycosyltransferase involves in plant chemical defense, Weijia Cheng, Xueting Fang, Zhifeng Guan, Yan Yao, Zhenni Xu, Yunya Bi, Kexin Ren, Jiwen Li, Fangfang Chen, Xiangsong Chen, Weihua Ma, Zhaohui Chu, Zixin Deng, Zhengyu Zhang, Li Lu, 2023
Characterization of benzylisoquinoline alkaloid methyltransferases in Liriodendron chinense provides insights into the phylogenic basis of angiosperm alkaloid diversity, Weijia Cheng, Yan Yao, Qiuxia Wang, Xiaosa Chang, Zhuolin Shi, Xueting Fang, Fangfang Chen, Shixin Chen, Yonghong Zhang, Fan Zhang, Dongqing Zhu, Zixin Deng, Li Lu, 2022
EGR1 Addiction in Diffuse Large B-cell Lymphoma, Kimpara S, Lu L, Hoang NM, Zhu F, Bates PD, Daenthanasanmak A, Zhang S, Yang DT, Kelm A, Liu Y, Li Y, Rosiejka A, Kondapelli A, Bebel S, Chen M, Waldmann TA, Capitini CM, Rui L, 2021
Inhibition of the STAT3 target SGK1 sensitizes diffuse large B cell lymphoma cells to AKT inhibitors, Li Lu, Fen Zhu, Yangguang Li, Shuichi Kimpara, Nguyet Minh Hoang, Sheida Pourdashti, Lixin Rui, 2019
The plant-specific histone residue Phe41 is important for genome-wide H3.1 distribution, Li Lu, Xiangsong Chen, Shuiming Qian, Xuehua Zhong, 2018
Gene regulation and suppression of type I interferon signaling by STAT3 in diffuse large B cell lymphoma, Li Lu, Fen Zhu, Meili Zhang, Yangguang Li, Amanda C. Drennan, Shuichi Kimpara, Ian Rumball, Christopher Selzer, Hunter Cameron, Ashley Kellicut, Amanda Kelm, Fangyu Wang, Thomas A Waldmann, Lixin Rui, 2018
Systematic identification of Ctr9 regulome in ERα-positive breast cancer, Zeng H, Lu L, Chan NT, Horswill M, Ahlquist P, Zhong X, Xu W, 2016
High-resolution mapping of H4K16 and H3K23 acetylation reveals conserved and unique distribution patterns in Arabidopsis and rice, Li Lu, Xiangsong Chen, Dean Sanders, Shuiming Qian, Xuehua Zhong, 2015
CRISPR-P: A web tool for synthetic single-guide RNA design of CRISPR-system in plants, Yang Lei, Li Lu, Hai-Yang Liu, Sen Li, Feng Xing, Ling-Ling Chen, 2014
Natural variation and artificial selection in four genes determine grain shape in rice, Li Lu, Di Shao, Xianjing Qiu, Liang Sun, Xiangchun Zhou, Wenhao Yan, Lin Yang, Yuqing

生物合成基因组学代谢工程天然产物植物生物学合成生物学生物信息学分子生物学生物农药香料

邓子新 - 武汉大学

孙宇辉 - 武汉大学

虞沂 - 武汉大学

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