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施回
Animal Sciences
浙江大学
浙江
Language: 英语, 中文
动物
消化器官
发育
疾病
斑马鱼
肝脏
神经母细胞瘤
基因表达
细胞模型
机制
Areas of Focus
- 动物消化器官发育与疾病
Work Experience
- 2014-2020 - 博士后研究员 - 哈佛大学医学院Dana-Farber肿瘤研究所
Academic Background & Achievements
- 2009 - 浙江大学动物医学专业学士学位
- 2014 - 浙江大学农学博士学位
- 博士后研究: 哈佛大学医学院Dana-Farber肿瘤研究所
Publications
- ARID1A loss in neuroblastoma promotes the adrenergic-to-mesenchymal transition by regulating enhancer-mediated gene expression, Shi H*, Tao T*, Abraham BJ, Durbin AD, Zimmerman MW, Kadoch C, Look AT., 2020
- Ganglioneuromas are driven by activated AKT and can be therapeutically targeted with mTOR inhibitors, Tao T*, Shi H*, Wang M, Perez-Atayde AR, London WB, Gutierrez A, Lemos B, Durbin AD, Look AT., 2020
- LIN28B regulates transcription and potentiates MYCN-induced neuroblastoma through binding to ZNF143 at target gene promotors, Tao T*, Shi H*, Mariani L, Abraham BJ, Durbin AD, Zimmerman MW, Powers JT, Missios P, Ross KN, Perez-Atayde AR, Bulyk ML, Young RA, Daley GQ, Look AT., 2020
- The pre-rRNA processing factor DEF is rate limiting for the pathogenesis of MYCN-driven neuroblastoma, Tao T*, Sondalle SB*, Shi H*, Zhu S, Perez-Atayde AR, Peng J, Baserga SJ, Look AT., 2017
- A naturally occurring 4-bp deletion in the intron 4 of p53 creates a spectrum of novel p53 isoforms with anti-apoptosis function, Shi H, Tao T, Huang D, Ou Z, Chen J, Peng J., 2015
- Def defines a nucleolar pathway that leading p53 to proteasome-independent degradation, Tao T*, Shi H*, Guan Y, Huang D, Chen Y, Lane DP, Chen J, Peng J., 2013
- Def functions as a cell autonomous factor in organogenesis of digestive organs in zebrafish, Tao T*, Shi H*, Huang D, Peng J., 2013
- Targeting ganglioneuromas with mTOR inhibitors, Tao T, Shi H, Durbin AD, Look AT., 2021
- Capn3 depletion causes Chk1 and Wee1 accumulation and disrupts synchronization of cell cycle reentry during liver regeneration after partial hepatectomy, Chen F, Huang D, Shi H, Wang Y, Peng J., 2020
- PTC-bearing mRNA elicits a genetic compensation response via Upf3a and COMPASS components, Ma Z, Zhu P, Shi H, Guo L, Zhang Q, Chen Y, Chen S, Zhang Z, Peng J, Chen J., 2019
- Loss of ATRX cooperates with p53-Deficiency to promote the development of sarcomas and other malignancies, Oppel F*, Tao T*, Shi H, Ross KN, Zimmerman MW, He S, Tong G, Aster JC, Look AT., 2019
- Sas10 controls ribosome biogenesis by stabilizing Mpp10 and delivering the Mpp10-Imp3-Imp4 complex to nucleolus, Zhao S, Chen Y, Chen F, Huang D, Shi H, Lo LJ, Chen J, Peng J., 2019
- Phosphorylation of Def regulates nucleolar p53 turnover and cell-cycle progression through Def recruitment of Calpain3, Guan Y, Huang D, Chen F, Gao C, Tao T, Shi H, Zhao S, Liao Z, Lo L, Wang Y, Chen J, Peng J., 2016
- The role of mesodermal signals during liver organogenesis in zebrafish, Niu X, Shi H, Peng J., 2010
