Areas of Focus
- 运用核磁共振技术,蛋白化学,分子生物学以及细胞生物学等多种研究手段,研究构建神经突触信号传导复合体的分子基础和动态调控,以及相关蛋白的传输。
Work Experience
- 1994-1995 - 加拿大安大略肿瘤研究所 - 博士后研究
- 1995 - 香港科技大学 - 助理教授
- 2000 - 香港科技大学 - 副教授
- 2004 - 香港科技大学 - 教授
- 2005 - 中国科学院 - 海外评审专家
Publications
- Solution Structure of the Extended Neuronal Nitric Oxide Synthase PDZ Domain Complexed with an Associated Peptide, Tochio, H., Zhang, Q., Mandal, P., Li., M., and Zhang, M., 1999
- An Auto-Inhibitory Mechanism for Non-Syntaxin SNARE Proteins Revealed by the Structure of Ykt6p, Tochio, T., Tsui, M. M. K., Banfield, D. K., and Zhang, M., 2001
- Tandem PDZ repeats in glutamate receptor interacting proteins have a novel mode of PDZ domain-mediated target binding, Feng, W., Shi, Y., Li, M. Zhang, M., 2003
- Hetero-tetrameric L27 (Lin-2, Lin-7) domain complexes as organization platforms for supra-molecular assemblies, Feng, W., Long, J.-F., Fan, J.-S., Tetsuya, S., Zhang, M., 2004
- Auto-inhibition of X11s/Mints Scaffold Proteins Revealed by the Closed Conformation of the PDZ Tandem, Long, J.-F., Feng, W., Wang, R., Chan, L.-N., Ip, F.C.F., Xia, J., Ip, N., Zhang, M., 2005
Awards
- Croucher基金会高级研究人员奖 (2003-2004)