Professor | 张端午 | 数字化转型顾问

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Name	张端午
Contact Information	duanwu@fudan.edu.cn
Language ability	中文, 英语
Province	上海

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Name

张端午

Contact Information

duanwu@fudan.edu.cn

Language ability

中文, 英语

Province

上海

University/Lab Affiliation and Title	复旦大学
Faculty	Biomedical Sciences
Academic Background & Achievements	2005.9-2009.9 博士：厦门大学 / 美国Scripps研究所 2001.9-2005.7 学士：厦门大学，生命科学学院发表SCI论文20余篇，篇均IF>20 被引用超过3000次担任Front Immunol杂志编委上海市免疫学会感染免疫专业委员会委员
Work Experience	2019.9-今 - 复旦大学 - 青年研究员，复旦大学生物医学研究院和附属儿科医院双聘PI 2015.11-2019.8 - 美国德克萨斯大学西南医学中心 - Instructor 2012.9-2015.10 - 美国德克萨斯大学西南医学中心 - 博士后 2009.10-2012.8 - 厦门大学 - 博士后
Awards	ELSEVIER出版社期刊杰出审稿人奖（2016）美国德克萨斯大学西南医学中心博士后研究奖（2014）国家自然科学奖二等奖（第2完成人）（2013）教育部自然科学奖一等奖（第2完成人）（2010）全国百篇优秀博士论文奖（2012）全国卢嘉锡优秀研究生奖（2009）

University/Lab Affiliation and Title

复旦大学

Faculty

Biomedical Sciences

Academic Background & Achievements

2005.9-2009.9 博士：厦门大学 / 美国Scripps研究所
2001.9-2005.7 学士：厦门大学，生命科学学院
发表SCI论文20余篇，篇均IF>20
被引用超过3000次
担任Front Immunol杂志编委
上海市免疫学会感染免疫专业委员会委员

Work Experience

2019.9-今 - 复旦大学 - 青年研究员，复旦大学生物医学研究院和附属儿科医院双聘PI
2015.11-2019.8 - 美国德克萨斯大学西南医学中心 - Instructor
2012.9-2015.10 - 美国德克萨斯大学西南医学中心 - 博士后
2009.10-2012.8 - 厦门大学 - 博士后

Awards

ELSEVIER出版社期刊杰出审稿人奖（2016）
美国德克萨斯大学西南医学中心博士后研究奖（2014）
国家自然科学奖二等奖（第2完成人）（2013）
教育部自然科学奖一等奖（第2完成人）（2010）
全国百篇优秀博士论文奖（2012）
全国卢嘉锡优秀研究生奖（2009）

Areas of Focus	肿瘤免疫天然免疫免疫细胞发育分化 T细胞功能与耗竭
Publications	RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis, Zhang D, Shao J, Lin J, Zhang N, Lu BJ, Lin SC, Dong MQ, Han J, 2009 Receptor-interacting protein (RIP) kinase family, Zhang D, Lin J, Han J, 2010 Programmed necrosis, backup to and competitor with apoptosis in the immune system, Han J, Zhong CQ, Zhang D, 2011 Multiple death pathways in TNF-treated fibroblasts: RIP3- and RIP1-dependent and independent routes, Zhang D, Zheng M, Zhao J, Li YY, Huang Z, Li Z, Han J, 2011 A role of RIP3-mediated macrophage necrosis in atherosclerosis development, Lin J, Li H, Yang M, Ren J, Huang Z, Han F, Huang J, Ma J, Zhang D, Zhang Z, Wu J, Huang D, Qiao M, Jin G, Wu Q, Huang Y, Du J, Han J, 2013 Regulator of G-protein signaling 19 (RGS19) and its partner Gα-inhibiting activity polypeptide 3 (GNAI3) are required for zVAD-induced autophagy and cell death in L929 cells, Wu T, Li Y, Huang D, Han F, Zhang YY, Zhang D, Han J, 2014 Real-time resolution of point mutations that cause phenovariance in mice, Wang T, Zhan X, Bu CH, Lyon S, Pratt D, Hildebrand S, Choi JH, Zhang Z, Zeng M, Wang KW, Turer E, Chen Z, Zhang D, Yue T,...Beutler B, 2015 Skin-specific regulation of SREBP processing and lipid biosynthesis by glycerol kinase 5, Zhang D, Tomisato W, Su L, Sun L, Choi JH, Zhang Z, Wang KW, Zhan X, Choi M, Li X, Tang M, Castro-Perez JM, Hildebrand S, Murray AR, Moresco EMY, Beutler B, 2017 IgD class switching is initiated by microbiota and limited to mucosa-associated lymphoid tissue in mice, Choi JH, Wang KW, Zhang D, Zhan X, Wang T, Bu CH, Behrendt CL, Zeng M, Wang Y, Misawa T, Li X, Tang M, Zhan X, Scott L, Hildebrand S, Murray AR, Moresco EM, Hooper LV, Beutler B, 2017 Syndromic immune disorder caused by a viable hypomorphic allele of spliceosome component Snrnp40, Zhang D, Yue T, Choi JH, Nair-Gill E, Zhong X, Wang KW, Zhan X, Li X, Choi M, Tang M, Quan J, Hildebrand S, Moresco EMY, Beutler B, 2019 Enhanced susceptibility to chemically induced colitis caused by excessive endosomal TLR signaling in LRBA-deficient mice, Wang KW, Zhan X, McAlpine W, Zhang Z, Choi JH, Shi H, Misawa T, Yue T, Zhang D, Wang Y, Ludwig S, Russell J, Tang M, Li X, Murray AR, Moresco EMY, Turer EE, Beutler B, 2019 LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling

Areas of Focus

肿瘤免疫
天然免疫
免疫细胞发育分化
T细胞功能与耗竭

Publications

RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis, Zhang D, Shao J, Lin J, Zhang N, Lu BJ, Lin SC, Dong MQ, Han J*, 2009
Receptor-interacting protein (RIP) kinase family, Zhang D, Lin J, Han J*, 2010
Programmed necrosis, backup to and competitor with apoptosis in the immune system, Han J, Zhong CQ, Zhang D, 2011
Multiple death pathways in TNF-treated fibroblasts: RIP3- and RIP1-dependent and independent routes, Zhang D, Zheng M, Zhao J, Li YY, Huang Z, Li Z, Han J*, 2011
A role of RIP3-mediated macrophage necrosis in atherosclerosis development, Lin J, Li H, Yang M, Ren J, Huang Z, Han F, Huang J, Ma J, Zhang D, Zhang Z, Wu J, Huang D, Qiao M, Jin G, Wu Q, Huang Y, Du J*, Han J*, 2013
Regulator of G-protein signaling 19 (RGS19) and its partner Gα-inhibiting activity polypeptide 3 (GNAI3) are required for zVAD-induced autophagy and cell death in L929 cells, Wu T, Li Y, Huang D, Han F, Zhang YY, Zhang D*, Han J*, 2014
Real-time resolution of point mutations that cause phenovariance in mice, Wang T, Zhan X, Bu CH, Lyon S, Pratt D, Hildebrand S, Choi JH, Zhang Z, Zeng M, Wang KW, Turer E, Chen Z, Zhang D, Yue T,...Beutler B*, 2015
Skin-specific regulation of SREBP processing and lipid biosynthesis by glycerol kinase 5, Zhang D, Tomisato W, Su L, Sun L, Choi JH, Zhang Z, Wang KW, Zhan X, Choi M, Li X, Tang M, Castro-Perez JM, Hildebrand S, Murray AR, Moresco EMY, Beutler B*, 2017
IgD class switching is initiated by microbiota and limited to mucosa-associated lymphoid tissue in mice, Choi JH, Wang KW, Zhang D, Zhan X, Wang T, Bu CH, Behrendt CL, Zeng M, Wang Y, Misawa T, Li X, Tang M, Zhan X, Scott L, Hildebrand S, Murray AR, Moresco EM, Hooper LV, Beutler B*, 2017
Syndromic immune disorder caused by a viable hypomorphic allele of spliceosome component Snrnp40, Zhang D, Yue T, Choi JH, Nair-Gill E, Zhong X, Wang KW, Zhan X, Li X, Choi M, Tang M, Quan J, Hildebrand S, Moresco EMY, Beutler B*, 2019
Enhanced susceptibility to chemically induced colitis caused by excessive endosomal TLR signaling in LRBA-deficient mice, Wang KW, Zhan X, McAlpine W, Zhang Z, Choi JH, Shi H, Misawa T, Yue T, Zhang D, Wang Y, Ludwig S, Russell J, Tang M, Li X, Murray AR, Moresco EMY, Turer EE, Beutler B*, 2019
LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling

肿瘤免疫癌症炎症传染病免疫信号生物化学分子生物学细胞生物学转录组学蛋白质组学

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