Professor | 黄亿华 | 数字化转型顾问

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Name	黄亿华
Contact Information	yihuahuang@sun5.ibp.ac.cn
Language ability	英语, 中文
Province	北京

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Name

黄亿华

Contact Information

yihuahuang@sun5.ibp.ac.cn

Language ability

英语, 中文

Province

北京

University/Lab Affiliation and Title	中国科学院大学
Faculty	Life Sciences
Academic Background & Achievements	1998-07--2004-02 博士: 康奈尔大学 1995-09--1998-07 硕士: 北京大学 1990-09--1995-07 学士: 北京大学
Work Experience	2010.9-至今 - 中国科学院生物物理研究所 - 研究组长 2004.3-2010.8 - 美国德州大学西南医学中心/美国霍华德休斯医学研究所 - 博士后/助理研究员/讲师

University/Lab Affiliation and Title

中国科学院大学

Faculty

Life Sciences

Academic Background & Achievements

1998-07--2004-02 博士: 康奈尔大学
1995-09--1998-07 硕士: 北京大学
1990-09--1995-07 学士: 北京大学

Work Experience

2010.9-至今 - 中国科学院生物物理研究所 - 研究组长
2004.3-2010.8 - 美国德州大学西南医学中心/美国霍华德休斯医学研究所 - 博士后/助理研究员/讲师

Areas of Focus	膜蛋白结构生物学
Publications	Structure of the BAM complex and its implications for biogenesis of outer-membrane proteins, Han L, Zheng J, Wang Y, Yang X, Liu Y, Sun C, Cao B, Zhou H, Ni D, Lou J, Zhao Y, Huang Y, 2016 The Expression, Purification, and Structure Determination of BamA from E. coli, Ni D, Huang Y, 2015 Structure of the nonameric bacterial amyloid secretion channel, Cao B, Zhao Y, Kou Y, Ni D, Zhang XC, Huang Y, 2014 Structural basis for lipopolysaccharide insertion in the bacterial outer membrane, Qiao S, Luo Q, Zhao Y, Zhang XC, Huang Y, 2014 Refolding, crystallization and preliminary X-ray crystallographic studies of the β-barrel domain of BamA, a membrane protein essential for outer membrane protein biogenesis, Ni D, Yang K, Huang Y, 2014 Structural and functional analysis of the β-barrel domain of BamA from Escherichia coli, Ni D, Wang Y, Yang X, Zhou H, Hou X, Cao B, Lu Z, Zhao X, Yang K, Huang Y, 2014 Insights into pilus assembly and secretion from the structure and functional characterization of usher PapC, Huang Y, Smith B, Chen L, Baxter R, Deisenhofer J, 2009 Crystal structure of cryptochrome 3 from Arabidopsis thaliana and its implication for photolyase activity, Huang Y, Baxter R, Smith BS, Partch CL, Colbert CL, Deisenhofer J, 2006 Structural basis of caspase inhibition by XIAP: differential roles of the linker versus the BIR domain, Huang Y, Park YC, Rich RL, Segal D, Myszka DG, Wu H, 2001 Requirement of both the second and third BIR domains for the relief of X-linked inhibitor of apoptosis protein (XIAP)-mediated caspase inhibition by Smac, Huang Y, Rich R, Myszkat D, Wu H, 2003 Antagonizing XIAP-mediated caspase-3 inhibition: Achilles' heel of cancers?, Huang Y, Lu M, Wu H, 2004 Covalent inhibition revealed by the crystal structure of the p35/caspase-8 complex, Xu G, Cirilli M, Huang Y, Rich RL, Myszka DG, Wu H, 2001 Crystal structure of the BIR1 domain of XIAP In two crystal forms, Lin SC, Huang Y, Lo YC, Lu M, Wu H, 2007 XIAP induces NF-κB activation via the BIR1/TAB1 interaction and BIR1 dimerization, Lu M, Lin S, Huang Y, Kang YJ, Rich R, Lo YC, Myszka D, Han J, Wu H, 2007 Mutational analysis of the p35-caspase interaction: A bowstring kinetic model of caspase inhibition by p35, Xu G, Rich RL, Steegborn C, Min T, Huang Y, Myszka DG, Wu H, 2003 Calcium dependence of myocardial hypothermial tolerance on sources of activator, Wang S, Huang Y, Zhou Z, 1997

Areas of Focus

膜蛋白结构生物学

Publications

Structure of the BAM complex and its implications for biogenesis of outer-membrane proteins, Han L, Zheng J, Wang Y, Yang X, Liu Y, Sun C, Cao B, Zhou H, Ni D, Lou J, Zhao Y, Huang Y, 2016
The Expression, Purification, and Structure Determination of BamA from E. coli, Ni D, Huang Y, 2015
Structure of the nonameric bacterial amyloid secretion channel, Cao B, Zhao Y, Kou Y, Ni D, Zhang XC, Huang Y, 2014
Structural basis for lipopolysaccharide insertion in the bacterial outer membrane, Qiao S, Luo Q, Zhao Y, Zhang XC, Huang Y, 2014
Refolding, crystallization and preliminary X-ray crystallographic studies of the β-barrel domain of BamA, a membrane protein essential for outer membrane protein biogenesis, Ni D, Yang K, Huang Y, 2014
Structural and functional analysis of the β-barrel domain of BamA from Escherichia coli, Ni D, Wang Y, Yang X, Zhou H, Hou X, Cao B, Lu Z, Zhao X, Yang K, Huang Y, 2014
Insights into pilus assembly and secretion from the structure and functional characterization of usher PapC, Huang Y, Smith B, Chen L, Baxter R, Deisenhofer J, 2009
Crystal structure of cryptochrome 3 from Arabidopsis thaliana and its implication for photolyase activity, Huang Y, Baxter R, Smith BS, Partch CL, Colbert CL, Deisenhofer J, 2006
Structural basis of caspase inhibition by XIAP: differential roles of the linker versus the BIR domain, Huang Y, Park YC, Rich RL, Segal D, Myszka DG, Wu H, 2001
Requirement of both the second and third BIR domains for the relief of X-linked inhibitor of apoptosis protein (XIAP)-mediated caspase inhibition by Smac, Huang Y, Rich R, Myszkat D, Wu H, 2003
Antagonizing XIAP-mediated caspase-3 inhibition: Achilles' heel of cancers?, Huang Y, Lu M, Wu H, 2004
Covalent inhibition revealed by the crystal structure of the p35/caspase-8 complex, Xu G, Cirilli M, Huang Y, Rich RL, Myszka DG, Wu H, 2001
Crystal structure of the BIR1 domain of XIAP In two crystal forms, Lin SC, Huang Y, Lo YC, Lu M, Wu H, 2007
XIAP induces NF-κB activation via the BIR1/TAB1 interaction and BIR1 dimerization, Lu M, Lin S, Huang Y, Kang YJ, Rich R, Lo YC, Myszka D, Han J, Wu H, 2007
Mutational analysis of the p35-caspase interaction: A bowstring kinetic model of caspase inhibition by p35, Xu G, Rich RL, Steegborn C, Min T, Huang Y, Myszka DG, Wu H, 2003
Calcium dependence of myocardial hypothermial tolerance on sources of activator, Wang S, Huang Y, Zhou Z, 1997

膜蛋白质结构生物学 X射线晶体学生物发生机制功能运输

黄亿华 - 中国科学院大学

Area of Focus
膜 | 蛋白质 | 结构 | 生物学 | X射线 | 晶体学 | 生物发生 | 功能 | 机制 | 多糖

刘卫东 - 中国科学院大学

Area of Focus
蛋白质晶体学: 结构 | 功能 | 酶 | 结晶 | X射线 | 衍射 | 分子 | 生物学 | 生物化学 | 分析 | 蛋白质工程: 设计 | 修改 | 稳定性 | 活性 | 应用 | 微生物学: 细菌 | 真菌 | 病毒 | 培养 | 鉴定 | 遗传学 | 生物催化: 酶 | 反应 | 合成 | 降解 | 生物转化 | 工业

汪启胜 - 中国科学院大学

Area of Focus
同步辐射 | 技术 | 应用 | 生物大分子 | 晶体学 | X射线 | 蛋白质 | 晶体 | 数据采集 | 研究

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