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Dimitri Lavillette
Life Science
中国科学院大学
上海
Language: 英语, 法语, 中文
登革热
基孔肯雅
寨卡
致病机理
细胞机制
疫苗
特效药
共感染
病毒-病毒相互作用
新发病毒
Areas of Focus
- 登革热、基孔肯雅病毒和寨卡病毒致病的细胞机理
- 登革热、基孔肯雅病毒和寨卡病毒疫苗和特效药的开发
- 其他新发病毒Co-infection和virus-virus interaction相关研究
Work Experience
- 2014-11 至今 - 中科院上海巴斯德研究所 - 研究员
- 2012-11 到 2014-11 - 法国国家科学研究院 - 副教授
- 2011-01 到 2011-12 - 牛津大学Glycobiology研究所 - 访问学者
- 2003-05 到 2012-11 - 法国国家医学与健康研究院, 里昂高等师范学院 - 副教授
- 2001-02 到 2003-05 - 美国俄勒冈卫生科学大学 - 博士后
- 2000-11 到 2001-02 - 美国Mayo医学中心 - 项目访问学者
Academic Background & Achievements
- 2009-02 到 2009-12 研究指导资格 (HDR): 里昂高等师范学院
- 1997-10 到 2000-11 博士: 法国国家医学与健康科学研究院, 里昂高等师范学院
- 1994-09 到 1997-10 硕士: 里昂大学
- 1991-09 到 1994-09 学士: 第戎大学
Publications
- A protein coevolution method uncovers critical features of the Hepatitis C Virus fusion mechanism., Dimitri Lavillette, 2018
- Chronic infection of mosquito by Chikungunya virus increases its susceptibility to Zika, Dengue and Yellow fever viruses during coinfection., Dimitri Lavillette, 2017
- Specialization of hepatitis C virus envelope glycoproteins for B-lymphocytes in chronically infected patients., Dimitri Lavillette, 2016
- New insights into the understanding of hepatitis C virus entry and cell-to-cell transmission by using the ionophore Monensin A, Dimitri Lavillette, 2015
- The sheep tetherin paralog oBST2B blocks envelope glycoprotein incorporation into nascent retroviral virions., Dimitri Lavillette, 2015
- Low cross-neutralization of hepatitis C correlates with liver disease in immunocompromized patients, Dimitri Lavillette, 2015
- The mechanism of HCV entry into host cells., Dimitri Lavillette, 2015
- A Critical Interaction Between E1 and E2 Glycoproteins Determines Binding and Fusion Properties of Hepatitis C Virus During Cell Entry, Dimitri Lavillette, 2014
- Baboon envelope pseudotyped lentiviral vectors outperform VSV-G pseudotyped lentiviral vectors for gene transfer into cytokine-stimulated and resting hematopoietic stem cells, Dimitri Lavillette, 2014
- The Expression of the Hepatocyte SLAMF3 (CD229) Receptor Enhances the Hepatitis C Virus Infection, Dimitri Lavillette, 2014
- Up-Regulation of the ATP-Binding Cassette Transporter A1 Inhibits Hepatitis C Virus Infection., Dimitri Lavillette, 2014
- Virus-like particle vaccine induces cross-protection against human metapneumovirus infections in mice., Dimitri Lavillette, 2013
- The antimalarial ferroquine is an inhibitor of hepatitis C virus, Dimitri Lavillette, 2013
- Characterization of hepatitis C virus particle sub-populations reveals multiple usage of the scavenger receptor BI for entry steps, Dimitri Lavillette, 2012
- Matrigel-embedded 3D culture of Huh-7 cells as a hepatocyte-like polarized system to study hepatitis C virus cycle., Dimitri Lavillette, 2012
- Distinct roles in folding, CD81 receptor binding and viral entry for conserved histidine residues of hepatitis C virus glycoprotein E1 and E2., Dimitri Lavillette, 2012
- A Prime-Boost Strategy Using Virus-Like Particles Pseudotyped for HCV Proteins Triggers Broadly Neutralizing Antibodies in Macaques., Dimitri Lavillette, 2011
- EGFR and EphA2 are host factors for hepatitis C virus entry and possible targets for antiviral therapy., Dimitri Lavillette, 0201
Awards
- 上海“****”引进人才, 一等奖, 省级, 2015
- 中国科学院2015年度第二批“****”A类, 院级, 2015
