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付刚
Life Science
中国科学院大学
天津
Language: 中文, 英语
枯草芽孢杆菌
蛋白质表达
调控系统
生物制造
维生素
营养化学品
高效
表达系统
生物技术
微生物学
Areas of Focus
- 枯草芽孢杆菌高效蛋白质表达调控系统
- 维生素类营养化学品生物制造
Work Experience
- 2012-08~现在 - 中国科学院天津工业生物技术研究所 - 副研究员
- 2010-08~2012-07 - 天津药物研究院 - 研究实习员
Academic Background & Achievements
- 2007-09--2010-07 理学硕士: 南开大学
- 2003-09--2007-07 理学学士: 山东大学威海分校
Publications
- 代谢工程改造枯草芽孢杆菌高效生产MK-7, 付刚, 2022
- 发酵工业菌种的迭代创制, 付刚, 2022
- Going Beyond the Local Catalytic Activity Space of Chitinase Using a Simulation-Based Iterative Saturation Mutagenesis Strategy, 付刚, 2022
- 工业酶与绿色生物工艺的核心技术进展, 付刚, 2022
- An operator-based expression toolkit for Bacillus subtilis enables fine-tuning of gene expression and biosynthetic pathway regulation, 付刚, 2022
- 碱性蛋白酶SubC在枯草芽孢杆菌中的高效异源表达, 付刚, 2021
- Compensating Complete Loss of Signal Recognition Particle During Co-translational Protein Targeting by the Translation Speed and Accuracy, 付刚, 2021
- Biosynthesis and applications of curdlan, 付刚, 2021
- Signal Recognition Particle Suppressor Screening Reveals the Regulation of Membrane Protein Targeting by the Translation Rate, 付刚, 2021
- 肌酐酶在枯草芽孢杆菌中的异源表达及分泌机制, 付刚, 2020
- Hyper-secretion mechanism exploration of a heterologous creatinase in Bacillus subtilis, 付刚, 2020
- Enhanced production of d-psicose 3-epimerase in Bacillus subtilis by regulation of segmented fermentation, 付刚, 2020
- High-Efficiency Secretion and Directed Evolution of Chitinase BcChiA1 in Bacillus subtilis for the Conversion of Chitinaceous Wastes Into Chitooligosaccharides, 付刚, 2020
- High-efficiency expression and secretion of human FGF21 in Bacillus subtilis by intercalation of a mini-cistron cassette and combinatorial optimization of cell regulatory components, 付刚, 2019
- Systematic Screening of Optimal Signal Peptides for Secretory Production of Heterologous Proteins in Bacillus subtilis, 付刚, 2018
- 通过信号肽筛选优化耐高温α-淀粉酶在枯草芽孢杆菌中的分泌, 付刚, 2017
- High-Efficiency Secretion of beta-Mannanase in Bacillus subtilis through Protein Synthesis and Secretion Optimization, 付刚, 2017
- A new maltose-inducible high-performance heterologous expression system in Bacillus subtilis, 付刚, 2017
- Promoter Screening from Bacillus subtilis in Various Conditions Hunting for Synthetic Biology and Industrial Applications, 付刚, 2016
- High-level intra- and extra-cellular production of D-psicose 3-epimerase via a modified xylose-inducible expression system in Bacillus subtilis, 付刚, 2016
- A novel strategy for protein production using non-classical secretion pathway in Bacillus subtilis, 付刚, 2016
- Combinatorial Sec pathway analysis for improved heterologous protein secretion in Bacillus subtilis: identification of bottlenecks by systematic gene overexpression, 付刚, 2015
- Enhanced extracellular production of alpha-amylase in Bacillus subtilis by optimization of regulatory elements and over-expression of PrsA lipoprotein, 付刚, 2015
- Cloning, characterization and production of a novel lysozyme by different expression hosts, 付刚, 2014
- Cloning, Characterization, and Production of a Novel Lysozyme by Different Expression Hosts, 付刚, 2014
