Professor | 付刚 | 数字化转型顾问

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Name	付刚
Contact Information	fu_g@tib.cas.cn
Language ability	中文, 英语
Province	天津

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Name

付刚

Contact Information

fu_g@tib.cas.cn

Language ability

中文, 英语

Province

天津

University/Lab Affiliation and Title	中国科学院大学
Faculty	Life Sciences
Academic Background & Achievements	2007-09--2010-07 理学硕士: 南开大学 2003-09--2007-07 理学学士: 山东大学威海分校
Work Experience	2012-08~现在 - 中国科学院天津工业生物技术研究所 - 副研究员 2010-08~2012-07 - 天津药物研究院 - 研究实习员

University/Lab Affiliation and Title

中国科学院大学

Faculty

Life Sciences

Academic Background & Achievements

2007-09--2010-07 理学硕士: 南开大学
2003-09--2007-07 理学学士: 山东大学威海分校

Work Experience

2012-08~现在 - 中国科学院天津工业生物技术研究所 - 副研究员
2010-08~2012-07 - 天津药物研究院 - 研究实习员

Areas of Focus	枯草芽孢杆菌高效蛋白质表达调控系统维生素类营养化学品生物制造
Publications	代谢工程改造枯草芽孢杆菌高效生产MK-7, 付刚, 2022 发酵工业菌种的迭代创制, 付刚, 2022 Going Beyond the Local Catalytic Activity Space of Chitinase Using a Simulation-Based Iterative Saturation Mutagenesis Strategy, 付刚, 2022 工业酶与绿色生物工艺的核心技术进展, 付刚, 2022 An operator-based expression toolkit for Bacillus subtilis enables fine-tuning of gene expression and biosynthetic pathway regulation, 付刚, 2022 碱性蛋白酶SubC在枯草芽孢杆菌中的高效异源表达, 付刚, 2021 Compensating Complete Loss of Signal Recognition Particle During Co-translational Protein Targeting by the Translation Speed and Accuracy, 付刚, 2021 Biosynthesis and applications of curdlan, 付刚, 2021 Signal Recognition Particle Suppressor Screening Reveals the Regulation of Membrane Protein Targeting by the Translation Rate, 付刚, 2021 肌酐酶在枯草芽孢杆菌中的异源表达及分泌机制, 付刚, 2020 Hyper-secretion mechanism exploration of a heterologous creatinase in Bacillus subtilis, 付刚, 2020 Enhanced production of d-psicose 3-epimerase in Bacillus subtilis by regulation of segmented fermentation, 付刚, 2020 High-Efficiency Secretion and Directed Evolution of Chitinase BcChiA1 in Bacillus subtilis for the Conversion of Chitinaceous Wastes Into Chitooligosaccharides, 付刚, 2020 High-efficiency expression and secretion of human FGF21 in Bacillus subtilis by intercalation of a mini-cistron cassette and combinatorial optimization of cell regulatory components, 付刚, 2019 Systematic Screening of Optimal Signal Peptides for Secretory Production of Heterologous Proteins in Bacillus subtilis, 付刚, 2018 通过信号肽筛选优化耐高温α-淀粉酶在枯草芽孢杆菌中的分泌, 付刚, 2017 High-Efficiency Secretion of beta-Mannanase in Bacillus subtilis through Protein Synthesis and Secretion Optimization, 付刚, 2017 A new maltose-inducible high-performance heterologous expression system in Bacillus subtilis, 付刚, 2017 Promoter Screening from Bacillus subtilis in Various Conditions Hunting for Synthetic Biology and Industrial Applications, 付刚, 2016 High-level intra- and extra-cellular production of D-psicose 3-epimerase via a modified xylose-inducible expression system in Bacillus subtilis, 付刚, 2016 A novel strategy for protein production using non-classical secretion pathway in Bacillus subtilis, 付刚, 2016 Combinatorial Sec pathway analysis for improved heterologous protein secretion in Bacillus subtilis: identification of bottlenecks by systematic gene overexpression, 付刚, 2015 Enhanced extracellular production of alpha-amylase in Bacillus subtilis by optimization of regulatory elements and over-expression of PrsA lipoprotein, 付刚, 2015 Cloning, characterization and production of a novel lysozyme by different expression hosts, 付刚, 2014 Cloning, Characterization, and Production of a Novel Lysozyme by Different Expression Hosts, 付刚, 2014

Areas of Focus

枯草芽孢杆菌高效蛋白质表达调控系统
维生素类营养化学品生物制造

Publications

代谢工程改造枯草芽孢杆菌高效生产MK-7, 付刚, 2022
发酵工业菌种的迭代创制, 付刚, 2022
Going Beyond the Local Catalytic Activity Space of Chitinase Using a Simulation-Based Iterative Saturation Mutagenesis Strategy, 付刚, 2022
工业酶与绿色生物工艺的核心技术进展, 付刚, 2022
An operator-based expression toolkit for Bacillus subtilis enables fine-tuning of gene expression and biosynthetic pathway regulation, 付刚, 2022
碱性蛋白酶SubC在枯草芽孢杆菌中的高效异源表达, 付刚, 2021
Compensating Complete Loss of Signal Recognition Particle During Co-translational Protein Targeting by the Translation Speed and Accuracy, 付刚, 2021
Biosynthesis and applications of curdlan, 付刚, 2021
Signal Recognition Particle Suppressor Screening Reveals the Regulation of Membrane Protein Targeting by the Translation Rate, 付刚, 2021
肌酐酶在枯草芽孢杆菌中的异源表达及分泌机制, 付刚, 2020
Hyper-secretion mechanism exploration of a heterologous creatinase in Bacillus subtilis, 付刚, 2020
Enhanced production of d-psicose 3-epimerase in Bacillus subtilis by regulation of segmented fermentation, 付刚, 2020
High-Efficiency Secretion and Directed Evolution of Chitinase BcChiA1 in Bacillus subtilis for the Conversion of Chitinaceous Wastes Into Chitooligosaccharides, 付刚, 2020
High-efficiency expression and secretion of human FGF21 in Bacillus subtilis by intercalation of a mini-cistron cassette and combinatorial optimization of cell regulatory components, 付刚, 2019
Systematic Screening of Optimal Signal Peptides for Secretory Production of Heterologous Proteins in Bacillus subtilis, 付刚, 2018
通过信号肽筛选优化耐高温α-淀粉酶在枯草芽孢杆菌中的分泌, 付刚, 2017
High-Efficiency Secretion of beta-Mannanase in Bacillus subtilis through Protein Synthesis and Secretion Optimization, 付刚, 2017
A new maltose-inducible high-performance heterologous expression system in Bacillus subtilis, 付刚, 2017
Promoter Screening from Bacillus subtilis in Various Conditions Hunting for Synthetic Biology and Industrial Applications, 付刚, 2016
High-level intra- and extra-cellular production of D-psicose 3-epimerase via a modified xylose-inducible expression system in Bacillus subtilis, 付刚, 2016
A novel strategy for protein production using non-classical secretion pathway in Bacillus subtilis, 付刚, 2016
Combinatorial Sec pathway analysis for improved heterologous protein secretion in Bacillus subtilis: identification of bottlenecks by systematic gene overexpression, 付刚, 2015
Enhanced extracellular production of alpha-amylase in Bacillus subtilis by optimization of regulatory elements and over-expression of PrsA lipoprotein, 付刚, 2015
Cloning, characterization and production of a novel lysozyme by different expression hosts, 付刚, 2014
Cloning, Characterization, and Production of a Novel Lysozyme by Different Expression Hosts, 付刚, 2014

枯草芽孢杆菌蛋白质表达调控系统生物制造维生素营养化学品高效表达系统生物技术微生物学

陈启明 - 上海大学

黄静 - 华东师范大学

陈金春 - 清华大学

Area of Focus
微生物学 | 工业 | 生物化学 | 工程 | 制药 | 生物材料 | 研究 | 生物技术 | 生产 | 应用

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