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刘然
Life Science
中国科学院大学
广东
Language: 中文, 英语
基因工程
生物合成
代谢途径
生物技术
微生物工程
疾病机制
病原体相互作用
生化过程
细胞生物学
生物医学研究
Areas of Focus
- 合成生物学
- 代谢工程
- 微生物与疾病的相互关系
Work Experience
- 2020-09~现在 - 中国科学院深圳先进技术研究院 - 副研究员
- 2012-07~2016-08 - 武汉臻智生物科技有限公司 - 研发部经理
Academic Background & Achievements
- 2016-09--2020-06 博士: 武汉大学
- 2010-09--2012-06 硕士: 武汉大学
- 2006-09--2010-06 学士: 四川农业大学
Publications
- New Insights of Corynebacterium kroppenstedtii in Granulomatous Lobular Mastitis based on Nanopore Sequencing, 第5作者, 2022
- 3 beta-Hydroxysteroid dehydrogenase expressed by gut microbes degrades testosterone and is linked to depression in males, 第2作者, 2022
- 构建链霉菌无细胞平台挖掘套索肽类天然产物, 通讯作者, 2022
- Evaluation and optimization of analytical procedure and sample preparation for polar Streptomyces albus J1074 metabolome profiling, 第5作者, 2022
- Increasing the heterologous production of spinosad in Streptomyces albus J1074 by regulating biosynthesis of its polyketide skeleton, 通讯作者, 2021
- The concordance between the evolutionary trend and the clinical manifestation of the two SARS-CoV-2 variants, 第2作者, 2021
- Harnessing in vitro platforms for natural product research: in vitro driven rational engineering and mining (iDREAM), 第1作者, 2021
- Promising methods for detection of novel coronavirus SARS‐CoV‐2, 第11作者, 2020
- A Cell‐Free Platform Based on Nisin Biosynthesis for Discovering Novel Lanthipeptides and Guiding their Overproduction In Vivo, 第1作者, 2020
- Nanopore Targeted Sequencing for the Accurate and Comprehensive Detection of SARS‐CoV‐2 and Other Respiratory Viruses, 第5作者, 2020
- Genomics-driven discovery of the biosynthetic gene cluster of maduramicin and its overproduction in Actinomadura sp. J1-007, 第1作者, 2020
- Aglycone Polyether Nanchangmycin and Its HomologuesExhibit Apoptotic and Antiproliferative Activities against CancerStem Cells, 第3作者, 2018
- Streptomyces species: Ideal chassis for natural product discovery and overproduction, 第1作者, 2018
- Modification of epsilon-poly-L-lysine in vivo to reduce self-toxicity and enhance antibiotic overproduction, 第4作者, 2018
- Metabolic Engineering of Fatty acyl-ACP Reductase-Dependent Pathway to Improve Fatty Alcohol Production in Escherichia coli., 第1作者, 2013
Awards
- 生物基法尼烯为前体合成维生素E的创新工艺, 一等奖, 省级, 2019
