Areas of Focus
- 微生物天然产物生物合成的酶学机制及分子设计
- 从事微生物次级代谢产物的生物合成及定向改造
- 微生物核酸酶的酶学机制及基因检测开发
Work Experience
- 2020 -迄今 上海交通大学生命科学技术学院，副研究员
- 2015-2019 上海交通大学生命科学技术学院，助理研究员
- 2013-2015 武汉大学药学院，博士后/助理研究员
Academic Background & Achievements
- 2010-2011 美国加州大学洛杉矶分校，化学与生物分子工程系，交流，导师：唐奕
- 2007-2012 上海交通大学生命科学技术学院，微生物学，博士，导师：周秀芬
- 2003-2007 上海交通大学生命科学技术学院，生物技术，本科
- 主持国家自然科学基金，重点研发计划子课题
Publications
- Mesophilic Argonaute-based isothermal detection of SARS-CoV-2, 刘倩, 2022
- Argonaute-integrated isothermal amplification for rapid, portable, multiplex detection of SARS-CoV-2 and influenza viruses, 刘倩, 2022
- Loosely-packed dynamical structures with partially-melted surface being the key for thermophilic argonaute proteins achieving high DNA-cleavage activity, 刘倩, 2022
- Argonaute integrated single-tube PCR system enables supersensitive detection of rare mutations, 刘倩, 2021
- Utility of B‑Factors in Protein Science: Interpreting Rigidity, Flexibility, and Internal Motion and Engineering Thermostability, 刘倩, 2018
- The state-of-the-art strategies of protein engineering for enzyme stabilization, 刘倩, 2018
- Argonaute with stepwise endonuclease activity promotes specific and multiplex nucleic acid detection, 刘倩, 2021
- Probing and Engineering the Fatty Acyl Substrate Selectivity of Starter Condensation Domains of Nonribosomal Peptide Synthetases in Lipopeptide Biosynthesis, 刘倩, 2019
- A hyperthermophilic Argonaute from Ferroglobus placidus with specificity on guide binding pattern, 刘倩, 2021
- Characterization of protein interaction surface on fatty acyl selectivity of starter condensation domain in lipopeptide biosynthesis, 刘倩, 2019
Awards
- 2016年，上海市科委青年科技英才扬帆计划
- 2016年，上海交通大学晨星青年学者奖励计划
