Areas of Focus
- 疫苗
- 小分子药物
- 治疗性抗体
Work Experience
- 2020-09~现在 - 中国科学院武汉病毒研究所 - 副研究员
- 2018-08~2020-09 - 中国科学院武汉病毒研究所 - 助理研究员
- 2016-08~2018-08 - 中国科学院武汉病毒研究所 - 博士后
- 2011-09~2016-06 - 南方医科大学 - 博士
Academic Background & Achievements
- 2011-09--2016-06 博士: 南方医科大学
- 成就 1: 青年年度人物, 2020
- 成就 2: 优秀毕业生, 2016
Publications
- Impact of SARS-CoV-2 envelope protein mutations on the pathogenicity of Omicron XBB, 第2作者, 2023
- Extracellular vesicles mediate antibody-resistant transmission of SARS-CoV-2, 第2作者, 2023
- Protection of the receptor binding domain (RBD) dimer against SARS-CoV-2 and its variants, 第11作者, 2023
- Danshensu alleviates pseudo-typed SARS-CoV-2 induced mouse acute lung inflammation, 第1作者, 2022
- Sertraline Is an Effective SARS-CoV-2 Entry Inhibitor Targeting the Spike Protein, 第11作者, 2022
- CoVac501, a self-adjuvanting peptide vaccine conjugated with TLR7 agonists, against SARS-CoV-2 induces protective immunity, 第10作者, 2022
- High-throughput screening of SARS-CoV-2 main and papain-like protease inhibitors, 第23作者, 2022
- Why is the SARS-CoV-2 Omicron variant milder?, 第3作者, 2022
- PARP1 Might Substitute HSF1 to Reactivate Latent HIV-1 by Binding to Heat Shock Element, 第9作者, 2022
- Identification, optimization, and biological evaluation of 3-O-β-chacotriosyl ursolic acid derivatives as novel SARS-CoV-2 entry inhibitors by targeting the prefusion state of spike protein, 未提及, 2022
- SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target, 第4作者, 2021
- SARS-CoV-2 ORF9b inhibits RIG-I-MAVS antiviral signaling by interrupting K63-linked ubiquitination of NEMO, 第3作者, 2021
- A pathogen-like antigen-based vaccine confers immune protection against SARS-CoV-2 in non-human primates, 第4作者, 2021
- Broad-spectrum antivirals of protoporphyrins inhibit the entry of highly pathogenic emerging viruses, 第2作者, 2021
- Drug Repurposing of Itraconazole and Estradiol Benzoate against COVID-19 by Blocking SARS-CoV-2 Spike Protein-Mediated Membrane Fusion, 第2作者, 2021
- Antiviral Bafilomycins from a Feces-Inhabiting Streptomyces sp., 第3作者, 2021
- Axial Chiral Binaphthoquinone and Perylenequinones from the Stromata of Hypocrella bambusae Are SARS-CoV-2 Entry Inhibitors, 第11作者, 2021
- High-throughput screening identifies established drugs as SARS-CoV-2 PLpro inhibitors, 第4作者, 2021
- The seafood Musculus senhousei shows anti-influenza A virus activity by targeting virion envelope lipids, 第4作者, 2020
- Salvianolic acid C potently inhibits SARS-CoV-2 infection by blocking the formation of six-helix bundle core of spike protein, 第2作者, 2020
- Development of horse neutralizing immunoglobulin and immunoglobulin fragments against Junin virus, 第1作者, 2020
- Immunoglobulin fragment F(ab')2 against RBD potently neutralizes SARS-CoV-2 in vitro, 第1作者, 2020
- Comprehensive Interactome Analysis Reveals that STT3B Is Required for N-Glycosylation of Lassa Virus Glycoprotein, 第5作者, 2019
- Heat shock factor 1 suppresses the HIV-induced inflammatory response by inhibiting nuclear factor-κB, 第1作者, 2018
Awards
- 青年年度人物 (2020): 研究所
- 优秀毕业生 (2016): 研究所