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石磊
Life Science
中国科学院大学
云南
Language: 中文, 英语
表观遗传学
神经系统
进化
发育
调控
机制
神经生物学
遗传学
研究
生物学
Areas of Focus
- 神经系统进化发育的表观调控机制
Work Experience
- 2020-10~现在 - 中国科学院昆明动物研究所 - 研究员
- 2019-03~2020-10 - 美国Salk生物研究所 - 博士后
- 2015-07~2019-02 - 美国密歇根大学安娜堡分校 - 博士后
- 2012-07~2015-07 - 中国科学院昆明动物研究所 - 助理研究员
- 2007-09~2012-06 - 中国科学院昆明动物研究所 - 博士
- 2003-09~2007-06 - 西南大学 - 学士
Academic Background & Achievements
- 2007-09--2012-06 博士: 中国科学院昆明动物研究所
- 2003-09--2007-06 学士: 西南大学
Publications
- In vivo partial reprogramming of myofibers promotes muscle regeneration by remodeling the stem cell niche, NATURE COMMUNICATIONS, 2021
- Chemical combinations potentiate human pluripotent stem cell-derived 3D pancreatic progenitor clusters toward functional β cells, NATURE COMMUNICATIONS, 2021
- Symmetric neural progenitor divisions require chromatin-mediated homologous recombination DNA repair by Ino80, NATURE COMMUNICATIONS, 2020
- Transgenic rhesus monkeys carrying the human MCPH1 gene copies show human-like neoteny of brain development, NATIONAL SCIENCE REVIEW: ENGLISH EDITION, 2019
- Robust elimination of genome-damaged cells safeguards against brain somatic aneuploidy following Knl1 deletion, NATURE COMMUNICATIONS, 2019
- Generation of blastocyst-like structures from mouse embryonic and adult cell cultures, CELL, 2019
- A transgenic monkey model for the study of human brain evolution, ZOOLOGICAL RESEARCH, 2019
- Regional Selection of the Brain Size Regulating Gene CASC5 Provides New Insight into Human Brain Evolution, HUMAN GENETICS, 2017
- Comparative Methylome Analyses Identify Epigenetic Regulatory Loci of Human Brain Evolution, MOLECULAR BIOLOGY AND EVOLUTION, 2016
- Sex Biased Gene Expression Profiling of Human Brains at Major Developmental Stages, SCIENTIFIC REPORTS, 2016
- Estrogen regulation of microcephaly genes and evolution of brain sexual dimorphism in primates, BMC EVOLUTIONARY BIOLOGY, 2015
- Human-Specific Hypomethylation of CENPJ, a Key Brain Size Regulator, MOLECULAR BIOLOGY AND EVOLUTION, 2014
- Analysis of common genetic variants identifies RELN as a risk gene for schizophrenia in Chinese population, WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY, 2013
- Functional divergence of the brain-size regulating gene MCPH1 during primate evolution and the origin of humans, BMC BIOLOGY, 2013
- Identification and functional characterization of a primate-specific E2F1 binding motif regulating MCPH1 expression, FEBS JOURNAL, 2012
- MCPH1/BRIT1 represses transcription of the human telomerase reverse transcriptase gene, GENE, 2012
- Genetic association and identification of a functional SNP at GSK3 beta for schizophrenia susceptibility, SCHIZOPHRENIA RESEARCH, 2011
