Professor | 石磊 | 数字化转型顾问

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Name	石磊
Contact Information	shilei@mail.kiz.ac.cn
Language ability	中文, 英语
Province	云南

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Name

石磊

Contact Information

shilei@mail.kiz.ac.cn

Language ability

中文, 英语

Province

云南

University/Lab Affiliation and Title	中国科学院大学
Faculty	Life Sciences
Academic Background & Achievements	2007-09--2012-06 博士: 中国科学院昆明动物研究所 2003-09--2007-06 学士: 西南大学
Work Experience	2020-10~现在 - 中国科学院昆明动物研究所 - 研究员 2019-03~2020-10 - 美国Salk生物研究所 - 博士后 2015-07~2019-02 - 美国密歇根大学安娜堡分校 - 博士后 2012-07~2015-07 - 中国科学院昆明动物研究所 - 助理研究员 2007-09~2012-06 - 中国科学院昆明动物研究所 - 博士 2003-09~2007-06 - 西南大学 - 学士

University/Lab Affiliation and Title

中国科学院大学

Faculty

Life Sciences

Academic Background & Achievements

2007-09--2012-06 博士: 中国科学院昆明动物研究所
2003-09--2007-06 学士: 西南大学

Work Experience

2020-10~现在 - 中国科学院昆明动物研究所 - 研究员
2019-03~2020-10 - 美国Salk生物研究所 - 博士后
2015-07~2019-02 - 美国密歇根大学安娜堡分校 - 博士后
2012-07~2015-07 - 中国科学院昆明动物研究所 - 助理研究员
2007-09~2012-06 - 中国科学院昆明动物研究所 - 博士
2003-09~2007-06 - 西南大学 - 学士

Areas of Focus	神经系统进化发育的表观调控机制
Publications	In vivo partial reprogramming of myofibers promotes muscle regeneration by remodeling the stem cell niche, NATURE COMMUNICATIONS, 2021 Chemical combinations potentiate human pluripotent stem cell-derived 3D pancreatic progenitor clusters toward functional β cells, NATURE COMMUNICATIONS, 2021 Symmetric neural progenitor divisions require chromatin-mediated homologous recombination DNA repair by Ino80, NATURE COMMUNICATIONS, 2020 Transgenic rhesus monkeys carrying the human MCPH1 gene copies show human-like neoteny of brain development, NATIONAL SCIENCE REVIEW: ENGLISH EDITION, 2019 Robust elimination of genome-damaged cells safeguards against brain somatic aneuploidy following Knl1 deletion, NATURE COMMUNICATIONS, 2019 Generation of blastocyst-like structures from mouse embryonic and adult cell cultures, CELL, 2019 A transgenic monkey model for the study of human brain evolution, ZOOLOGICAL RESEARCH, 2019 Regional Selection of the Brain Size Regulating Gene CASC5 Provides New Insight into Human Brain Evolution, HUMAN GENETICS, 2017 Comparative Methylome Analyses Identify Epigenetic Regulatory Loci of Human Brain Evolution, MOLECULAR BIOLOGY AND EVOLUTION, 2016 Sex Biased Gene Expression Profiling of Human Brains at Major Developmental Stages, SCIENTIFIC REPORTS, 2016 Estrogen regulation of microcephaly genes and evolution of brain sexual dimorphism in primates, BMC EVOLUTIONARY BIOLOGY, 2015 Human-Specific Hypomethylation of CENPJ, a Key Brain Size Regulator, MOLECULAR BIOLOGY AND EVOLUTION, 2014 Analysis of common genetic variants identifies RELN as a risk gene for schizophrenia in Chinese population, WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY, 2013 Functional divergence of the brain-size regulating gene MCPH1 during primate evolution and the origin of humans, BMC BIOLOGY, 2013 Identification and functional characterization of a primate-specific E2F1 binding motif regulating MCPH1 expression, FEBS JOURNAL, 2012 MCPH1/BRIT1 represses transcription of the human telomerase reverse transcriptase gene, GENE, 2012 Genetic association and identification of a functional SNP at GSK3 beta for schizophrenia susceptibility, SCHIZOPHRENIA RESEARCH, 2011

Areas of Focus

神经系统进化发育的表观调控机制

Publications

In vivo partial reprogramming of myofibers promotes muscle regeneration by remodeling the stem cell niche, NATURE COMMUNICATIONS, 2021
Chemical combinations potentiate human pluripotent stem cell-derived 3D pancreatic progenitor clusters toward functional β cells, NATURE COMMUNICATIONS, 2021
Symmetric neural progenitor divisions require chromatin-mediated homologous recombination DNA repair by Ino80, NATURE COMMUNICATIONS, 2020
Transgenic rhesus monkeys carrying the human MCPH1 gene copies show human-like neoteny of brain development, NATIONAL SCIENCE REVIEW: ENGLISH EDITION, 2019
Robust elimination of genome-damaged cells safeguards against brain somatic aneuploidy following Knl1 deletion, NATURE COMMUNICATIONS, 2019
Generation of blastocyst-like structures from mouse embryonic and adult cell cultures, CELL, 2019
A transgenic monkey model for the study of human brain evolution, ZOOLOGICAL RESEARCH, 2019
Regional Selection of the Brain Size Regulating Gene CASC5 Provides New Insight into Human Brain Evolution, HUMAN GENETICS, 2017
Comparative Methylome Analyses Identify Epigenetic Regulatory Loci of Human Brain Evolution, MOLECULAR BIOLOGY AND EVOLUTION, 2016
Sex Biased Gene Expression Profiling of Human Brains at Major Developmental Stages, SCIENTIFIC REPORTS, 2016
Estrogen regulation of microcephaly genes and evolution of brain sexual dimorphism in primates, BMC EVOLUTIONARY BIOLOGY, 2015
Human-Specific Hypomethylation of CENPJ, a Key Brain Size Regulator, MOLECULAR BIOLOGY AND EVOLUTION, 2014
Analysis of common genetic variants identifies RELN as a risk gene for schizophrenia in Chinese population, WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY, 2013
Functional divergence of the brain-size regulating gene MCPH1 during primate evolution and the origin of humans, BMC BIOLOGY, 2013
Identification and functional characterization of a primate-specific E2F1 binding motif regulating MCPH1 expression, FEBS JOURNAL, 2012
MCPH1/BRIT1 represses transcription of the human telomerase reverse transcriptase gene, GENE, 2012
Genetic association and identification of a functional SNP at GSK3 beta for schizophrenia susceptibility, SCHIZOPHRENIA RESEARCH, 2011

表观遗传学神经系统进化发育调控机制神经生物学遗传学研究生物学

侯羽君 - 同济大学

孙方霖 - 同济大学

Area of Focus
表观遗传学 | 分子机制 | 调控 | 异染色质 | 结构 | 功能 | 干细胞 | 衰老 | 网络 | 研究

史偈君 - 同济大学

Area of Focus
表观遗传学 | 多态性 | 基因表达 | 调控 | 发展 | 衰老 | 肿瘤异质性 | 诊断 | 治疗 | 多组学

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