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涂然
Life Science
中国科学院大学
天津
Language: 英语, 中文, 德语
筛选
高通量
微流控
合成生物学
蛋白质工程
酶
生物技术
微生物
基因工程
代谢工程
Areas of Focus
- 高通量筛选技术
- 合成生物学
- 蛋白质工程
Work Experience
- 2020-08~现在 - 中国科学院天津工业生物技术研究所 - 项目研究员
- 2014-08~2015-02 - 哈佛大学 - 访问学者
- 2010-09~现在 - 中国科学院天津工业生物技术研究所 - 副研究员
- 2006-07~2007-03 - 清华大学 - 博士后研究
- 2000-09~2001-04 - 北京大学 - 实习研究
Academic Background & Achievements
- 2007-04--2010-07 哲学博士: Jacobs University
- 2001-09--2006-06 理学博士: 中国农业大学
- 1996-09--2000-06 工学学士: 华南理工大学
Publications
- 液滴微流控技术在微生物工程菌株选育中的应用进展, 涂然, 2022
- Whole-cell biosensor and producer co-cultivation based microfludic platform for screening Saccharopolyspora erythraea with hyper erythromycin production, 涂然, 2022
- Recent advances in droplet microfluidics for enzyme and cell factory engineering, 涂然, 2021
- Antisense RNA Interference-Enhanced CRISPR/Cas9 Base Editing Method for Improving Base Editing Efficiency in Streptomyces lividans 66, 涂然, 2021
- Droplet-based microfluidic platform for high-throughput screening of Streptomyces, 涂然, 2021
- A high-throughput fluorescence assay for ketone detection and its applications in enzyme mining and protein engineering, 涂然, 2020
- Design and Reconstruction of Regulatory Parts for Fast-frowing Vibrio natriegens Synthetic Biology, 涂然, 2020
- High-Throughput Fluorescence Assay for Ketone Detectionand Its Applications in Enzyme Mining and Protein Engineering, 涂然, 2020
- Biosensor-enabled droplet microfluidic system for the rapid screening of 3-dehydroshikimic acid produced inEscherichia coli, 涂然, 2020
- 核黄素工业菌株高通量筛选方法的建立和应用, 涂然, 2020
- 一种基于微芯片快速生成双层乳化液滴的方法, 涂然, 2020
- Rapid isolation of antigen-specific B-cells using droplet microfluidics, 涂然, 2020
- Development of a Simple Colorimetric Assay for Determination of the Isoamyl Alcohol-Producing Strain, 涂然, 2020
- Genomic, transcriptomic, and metabolic characterizations of Escherichia coli adapted to branched-chain higher alcohol tolerance, 涂然, 2020
- Enhanced production of d-psicose 3-epimerase in Bacillus subtilis by regulation of segmented fermentation, 涂然, 2020
- A double-enzyme-coupled high-throughput assay for determination of isoamyl alcohol produced by microorganisms, 涂然, 2020
- Ultra-high-throughput picoliter-droplet microfluidics screening of the industrial cellulase-producing filamentous fungus Trichoderma reesei, 涂然, 2019
- 毕赤酵母液滴微流控高通量筛选方法的建立与应用, 涂然, 2019
- Development of a Synthetic 3-Dehydroshikimate Biosensor in Escherichia coli for Metabolite Monitoring and Genetic Screening, 涂然, 2019
- High-efficiency expression and secretion of human FGF21 in Bacillus subtilis by intercalation of a mini-cistron cassette and combinatorial optimization of cell regulatory components, 涂然, 2019
- Fluorescence-activated droplet sorting of lipolytic microorganisms using a compact optical system, 涂然, 2018
- Fluorescence-activated droplet sorting of lipolytic microorganisms using a compact optical system., 涂然, 2017
- Increasing activity and thermal resistance of Bacillus gibsonii alkaline protease (BgAP) by directed evolution, 涂然, 2013
