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张华威
Life Science
中国科学院大学
广东
Language: 英语, 中文
蛋白质
结构
功能
生物化学
分子生物学
药物开发
冷冻电镜
抑制剂
通道
途径
Areas of Focus
- 蛋白质结构和功能
- 新药研发
Work Experience
- 2023-05~现在 - 中国科学院深圳先进技术研究院 - 副研究员
- 2020-01~2023-04 - 南方科技大学 - 副研究员
- 2018-05~2018-07 - 斯坦福大学 - 访问学者
- 2012-07~2013-07 - 中国科学院上海应用物理研究所 - 研究助理
Academic Background & Achievements
- 2013-08--2017-07 博士: 香港中文大学
- 2009-09--2012-06 硕士: 复旦大学
- 2005-09--2009-06 学士: 贵州大学
Publications
- Cryo-EM structure of human heptameric pannexin 2 channel, Hang Zhang, Shiyu Wang, Zhenzhen Zhang, Mengzhuo Hou, Chunyu Du, Zhenye Zhao, Horst Vogel, Zhifang Li, Kaige Yan, Xiaokang Zhang, Jianping Lu, Yujie Liang, Shuguang Yuan, Daping Wang, Huawei Zhang, 2023
- Cryo-EM structures of ClC-2 chloride channel reveal the blocking mechanism of its specific inhibitor AK-42, Tao Ma, Lei Wang, Anping Chai, Chao Liu, Wenqiang Cui, Shuguang Yuan, Shannon Wing Ngor Au, Liang Sun, Xiaokang Zhang, Zhenzhen Zhang, Jianping Lu, Yuanzhu Gao, Peiyi Wang, Zhifang Li, Yujie Liang, Horst Vogel, Yu Tian Wang, Daping Wang, Kaige Yan, Huawei Zhang, 2023
- Applications and prospects of cryo-EM in drug discovery, Kong-Fu Zhu, Chuang Yuan, Yong-Ming Du, Kai-Lei Sun, Xiao-Kang Zhang, Horst Vogel, Xu-Dong Jia, Yuan-Zhu Gao, Qin-Fen Zhang, Da-Ping Wang, Hua-Wei Zhang, 2023
- Focusing on the hypoxia-inducible factor pathway: role, regulation, and therapy for osteoarthritis, Guo, Hanhan, Huang, Jianghong, Liang, Yujie, Wang, Daping, Zhang, Huawei, 2022
- Cryo-electron Tomography Reveals the Roles of FliY in Helicobacter pylori Flagellar Motor Assembly, Lu, Ping, Zhang, Huawei, Gao, Yuanzhu, Jia, Xudong, Liu, Zhe, Wang, Daping, Au, Shannon Wing Ngor, Zhang, Qinfen, 2022
- Expression and structural analysis of human neuroligin 2 and neuroligin 3 implicated in autism spectrum disorders, Zhang, Zhenzhen, Hou, Mengzhuo, Ou, Huaxing, Wang, Daping, Li, Zhifang, Zhang, Huawei, Lu, Jianping, 2022
- Cryo-EM Structure and Activator Screening of Human Tryptophan Hydroxylase 2, Zhu, Kongfu, Liu, Chao, Gao, Yuanzhu, Lu, Jianping, Wang, Daping, Zhang, Huawei, 2022
- Cryo-EM structures of Helicobacter pylori vacuolating cytotoxin A oligomeric assemblies at near-atomic resolution, Zhang, Kaiming, Zhang, Huawei, Li, Shanshan, Pintilie, Grigore D, Mou, TungChung, Gao, Yuanzhu, Zhang, Qinfen, van den Bedeme, Henry, Schmid, Michael F, Au, Shannon Wing Ngor, Chiu, Wah, 2019
- A putative spermidine synthase interacts with flagellar switch protein FliM and regulates motility in Helicobacter pylori, Zhang, Huawei, Lam, Kwok Ho, Lam, Wendy Wai Ling, Wong, Sandra Yuen Yuen, Chan, Vera Sau Fong, Au, Shannon Wing Ngor, 2017
- Helicobacter pylori does not use spermidine synthase to produce spermidine, Zhang, Huawei, Au, Shannon Wing Ngor, 2017
- The in vitro interaction of CmeA with CmeC, Zhang, HuaWei, Zeng, Ximin, Qi, Qi, Sun, KaiLei, Ma, ChongJun, Hu, XiaoJian, Lin, Jun, 2014
