Professor | 张华威 | 数字化转型顾问

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Name	张华威
Contact Information	hw.zhang@siat.ac.cn
Language ability	英语, 中文
Province	广东

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Name

张华威

Contact Information

hw.zhang@siat.ac.cn

Language ability

英语, 中文

Province

广东

University/Lab Affiliation and Title	中国科学院大学
Faculty	Life Sciences
Academic Background & Achievements	2013-08--2017-07 博士: 香港中文大学 2009-09--2012-06 硕士: 复旦大学 2005-09--2009-06 学士: 贵州大学
Work Experience	2023-05~现在 - 中国科学院深圳先进技术研究院 - 副研究员 2020-01~2023-04 - 南方科技大学 - 副研究员 2018-05~2018-07 - 斯坦福大学 - 访问学者 2012-07~2013-07 - 中国科学院上海应用物理研究所 - 研究助理

University/Lab Affiliation and Title

中国科学院大学

Faculty

Life Sciences

Academic Background & Achievements

2013-08--2017-07 博士: 香港中文大学
2009-09--2012-06 硕士: 复旦大学
2005-09--2009-06 学士: 贵州大学

Work Experience

2023-05~现在 - 中国科学院深圳先进技术研究院 - 副研究员
2020-01~2023-04 - 南方科技大学 - 副研究员
2018-05~2018-07 - 斯坦福大学 - 访问学者
2012-07~2013-07 - 中国科学院上海应用物理研究所 - 研究助理

Areas of Focus	蛋白质结构和功能新药研发
Publications	Cryo-EM structure of human heptameric pannexin 2 channel, Hang Zhang, Shiyu Wang, Zhenzhen Zhang, Mengzhuo Hou, Chunyu Du, Zhenye Zhao, Horst Vogel, Zhifang Li, Kaige Yan, Xiaokang Zhang, Jianping Lu, Yujie Liang, Shuguang Yuan, Daping Wang, Huawei Zhang, 2023 Cryo-EM structures of ClC-2 chloride channel reveal the blocking mechanism of its specific inhibitor AK-42, Tao Ma, Lei Wang, Anping Chai, Chao Liu, Wenqiang Cui, Shuguang Yuan, Shannon Wing Ngor Au, Liang Sun, Xiaokang Zhang, Zhenzhen Zhang, Jianping Lu, Yuanzhu Gao, Peiyi Wang, Zhifang Li, Yujie Liang, Horst Vogel, Yu Tian Wang, Daping Wang, Kaige Yan, Huawei Zhang, 2023 Applications and prospects of cryo-EM in drug discovery, Kong-Fu Zhu, Chuang Yuan, Yong-Ming Du, Kai-Lei Sun, Xiao-Kang Zhang, Horst Vogel, Xu-Dong Jia, Yuan-Zhu Gao, Qin-Fen Zhang, Da-Ping Wang, Hua-Wei Zhang, 2023 Focusing on the hypoxia-inducible factor pathway: role, regulation, and therapy for osteoarthritis, Guo, Hanhan, Huang, Jianghong, Liang, Yujie, Wang, Daping, Zhang, Huawei, 2022 Cryo-electron Tomography Reveals the Roles of FliY in Helicobacter pylori Flagellar Motor Assembly, Lu, Ping, Zhang, Huawei, Gao, Yuanzhu, Jia, Xudong, Liu, Zhe, Wang, Daping, Au, Shannon Wing Ngor, Zhang, Qinfen, 2022 Expression and structural analysis of human neuroligin 2 and neuroligin 3 implicated in autism spectrum disorders, Zhang, Zhenzhen, Hou, Mengzhuo, Ou, Huaxing, Wang, Daping, Li, Zhifang, Zhang, Huawei, Lu, Jianping, 2022 Cryo-EM Structure and Activator Screening of Human Tryptophan Hydroxylase 2, Zhu, Kongfu, Liu, Chao, Gao, Yuanzhu, Lu, Jianping, Wang, Daping, Zhang, Huawei, 2022 Cryo-EM structures of Helicobacter pylori vacuolating cytotoxin A oligomeric assemblies at near-atomic resolution, Zhang, Kaiming, Zhang, Huawei, Li, Shanshan, Pintilie, Grigore D, Mou, TungChung, Gao, Yuanzhu, Zhang, Qinfen, van den Bedeme, Henry, Schmid, Michael F, Au, Shannon Wing Ngor, Chiu, Wah, 2019 A putative spermidine synthase interacts with flagellar switch protein FliM and regulates motility in Helicobacter pylori, Zhang, Huawei, Lam, Kwok Ho, Lam, Wendy Wai Ling, Wong, Sandra Yuen Yuen, Chan, Vera Sau Fong, Au, Shannon Wing Ngor, 2017 Helicobacter pylori does not use spermidine synthase to produce spermidine, Zhang, Huawei, Au, Shannon Wing Ngor, 2017 The in vitro interaction of CmeA with CmeC, Zhang, HuaWei, Zeng, Ximin, Qi, Qi, Sun, KaiLei, Ma, ChongJun, Hu, XiaoJian, Lin, Jun, 2014

Areas of Focus

蛋白质结构和功能
新药研发

Publications

Cryo-EM structure of human heptameric pannexin 2 channel, Hang Zhang, Shiyu Wang, Zhenzhen Zhang, Mengzhuo Hou, Chunyu Du, Zhenye Zhao, Horst Vogel, Zhifang Li, Kaige Yan, Xiaokang Zhang, Jianping Lu, Yujie Liang, Shuguang Yuan, Daping Wang, Huawei Zhang, 2023
Cryo-EM structures of ClC-2 chloride channel reveal the blocking mechanism of its specific inhibitor AK-42, Tao Ma, Lei Wang, Anping Chai, Chao Liu, Wenqiang Cui, Shuguang Yuan, Shannon Wing Ngor Au, Liang Sun, Xiaokang Zhang, Zhenzhen Zhang, Jianping Lu, Yuanzhu Gao, Peiyi Wang, Zhifang Li, Yujie Liang, Horst Vogel, Yu Tian Wang, Daping Wang, Kaige Yan, Huawei Zhang, 2023
Applications and prospects of cryo-EM in drug discovery, Kong-Fu Zhu, Chuang Yuan, Yong-Ming Du, Kai-Lei Sun, Xiao-Kang Zhang, Horst Vogel, Xu-Dong Jia, Yuan-Zhu Gao, Qin-Fen Zhang, Da-Ping Wang, Hua-Wei Zhang, 2023
Focusing on the hypoxia-inducible factor pathway: role, regulation, and therapy for osteoarthritis, Guo, Hanhan, Huang, Jianghong, Liang, Yujie, Wang, Daping, Zhang, Huawei, 2022
Cryo-electron Tomography Reveals the Roles of FliY in Helicobacter pylori Flagellar Motor Assembly, Lu, Ping, Zhang, Huawei, Gao, Yuanzhu, Jia, Xudong, Liu, Zhe, Wang, Daping, Au, Shannon Wing Ngor, Zhang, Qinfen, 2022
Expression and structural analysis of human neuroligin 2 and neuroligin 3 implicated in autism spectrum disorders, Zhang, Zhenzhen, Hou, Mengzhuo, Ou, Huaxing, Wang, Daping, Li, Zhifang, Zhang, Huawei, Lu, Jianping, 2022
Cryo-EM Structure and Activator Screening of Human Tryptophan Hydroxylase 2, Zhu, Kongfu, Liu, Chao, Gao, Yuanzhu, Lu, Jianping, Wang, Daping, Zhang, Huawei, 2022
Cryo-EM structures of Helicobacter pylori vacuolating cytotoxin A oligomeric assemblies at near-atomic resolution, Zhang, Kaiming, Zhang, Huawei, Li, Shanshan, Pintilie, Grigore D, Mou, TungChung, Gao, Yuanzhu, Zhang, Qinfen, van den Bedeme, Henry, Schmid, Michael F, Au, Shannon Wing Ngor, Chiu, Wah, 2019
A putative spermidine synthase interacts with flagellar switch protein FliM and regulates motility in Helicobacter pylori, Zhang, Huawei, Lam, Kwok Ho, Lam, Wendy Wai Ling, Wong, Sandra Yuen Yuen, Chan, Vera Sau Fong, Au, Shannon Wing Ngor, 2017
Helicobacter pylori does not use spermidine synthase to produce spermidine, Zhang, Huawei, Au, Shannon Wing Ngor, 2017
The in vitro interaction of CmeA with CmeC, Zhang, HuaWei, Zeng, Ximin, Qi, Qi, Sun, KaiLei, Ma, ChongJun, Hu, XiaoJian, Lin, Jun, 2014

蛋白质结构功能生物化学分子生物学药物开发冷冻电镜抑制剂通道途径

曹骎 - 上海交通大学

曹骎 - 上海交通大学

蔡舒君 - 南方科技大学

Area of Focus
膜 | 重塑 | 结构 | 机理 | 原位 | 冷冻电镜 | 显微镜 | 方法 | 开发 | 生物大分子

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